相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Whole-genome doubling confers unique genetic vulnerabilities on tumour cells
Ryan J. Quinton et al.
NATURE (2021)
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
Devon A. Lukow et al.
DEVELOPMENTAL CELL (2021)
Structural Chromosome Instability: Types, Origins, Consequences, and Therapeutic Opportunities
Sebastian Omar Siri et al.
CANCERS (2021)
WFDC Protein: A Promising Diagnosis Biomarker of Ovarian Cancer
Chen Zhang et al.
JOURNAL OF CANCER (2021)
Acquisition of chromosome instability is a mechanism to evade oncogene addiction
Lorena Salgueiro et al.
EMBO MOLECULAR MEDICINE (2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution
Saioa Lopez et al.
NATURE GENETICS (2020)
DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons
Therese Wilhelm et al.
GENES (2020)
CKS1B as Drug Resistance-Inducing Gene-A Potential Target to Improve Cancer Therapy
Wenwen Shi et al.
FRONTIERS IN ONCOLOGY (2020)
The Cancer Aneuploidy Paradox: In the Light of Evolution
Kristine Salmina et al.
GENES (2019)
Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity
Chloe C. Lepage et al.
CANCERS (2019)
The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity
Andrea E. Tijhuis et al.
MOLECULAR CYTOGENETICS (2019)
Mild replication stress causes aneuploidy by deregulating microtubule dynamics in mitosis
Nicolas Boehly et al.
CELL CYCLE (2019)
What Is Karyotype Coding and Why Is Genomic Topology Important for Cancer and Evolution?
Christine J. Ye et al.
FRONTIERS IN GENETICS (2019)
Genomic and Functional Approaches to Understanding Cancer Aneuploidy
Alison M. Taylor et al.
CANCER CELL (2018)
Comprehensive Characterization of Cancer Driver Genes and Mutations
Matthew H. Bailey et al.
CELL (2018)
Chromosomal instability drives metastasis through a cytosolic DNA response
Samuel F. Bakhoum et al.
NATURE (2018)
Determinants and clinical implications of chromosomal instability in cancer
Laurent Sansregret et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations
David Tamborero et al.
GENOME MEDICINE (2018)
The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment
Samuel F. Bakhoum et al.
CELL (2018)
Tolerance of Chromosomal Instability in Cancer: Mechanisms and Therapeutic Opportunities
Eva Gronroos et al.
CANCER RESEARCH (2018)
Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation
Christopher Buccitelli et al.
GENOME RESEARCH (2017)
Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy
Teresa Davoli et al.
SCIENCE (2017)
Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer
Joe Ryan Delaney et al.
NATURE COMMUNICATIONS (2017)
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling
Inma M. Berenjeno et al.
NATURE COMMUNICATIONS (2017)
Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer
Laura L. Thompson et al.
CANCERS (2017)
The presence of extra chromosomes leads to genomic instability
Verena Passerini et al.
NATURE COMMUNICATIONS (2016)
Genome Stability Requires p53
Christine M. Eischen
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)
Difference Makers: Chromosomal Instability versus Aneuploidy in Cancer
Richard H. van Jaarsveld et al.
TRENDS IN CANCER (2016)
limma powers differential expression analyses for RNA-sequencing and microarray studies
Matthew E. Ritchie et al.
NUCLEIC ACIDS RESEARCH (2015)
Numerical chromosomal instability mediates susceptibility to radiation treatment
Samuel F. Bakhoum et al.
NATURE COMMUNICATIONS (2015)
Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset
Brinton Seashore-Ludlow et al.
CANCER DISCOVERY (2015)
Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution
Ashley M. Laughney et al.
CELL REPORTS (2015)
Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
David Endesfelder et al.
CANCER RESEARCH (2014)
Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial
Yi-Long Wu et al.
LANCET ONCOLOGY (2014)
DNA-Damage Response during Mitosis Induces Whole-Chromosome Missegregation
Samuel F. Bakhoum et al.
CANCER DISCOVERY (2014)
Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution
Sally M. Dewhurst et al.
CANCER DISCOVERY (2014)
A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis
Jason M. Sheltzer
CANCER RESEARCH (2013)
Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome
Teresa Davoli et al.
CELL (2013)
Karyotype Heterogeneity and Unclassified Chromosomal Abnormalities
H. H. Q. Heng et al.
CYTOGENETIC AND GENOME RESEARCH (2013)
Replication stress links structural and numerical cancer chromosomal instability
Rebecca A. Burrell et al.
NATURE (2013)
Emerging landscape of oncogenic signatures across human cancers
Giovanni Ciriello et al.
NATURE GENETICS (2013)
The Cancer Genome Atlas Pan-Cancer analysis project
John N. Weinstein et al.
NATURE GENETICS (2013)
Multi-layered cancer chromosomal instability phenotype
Anna V. Roschke et al.
FRONTIERS IN ONCOLOGY (2013)
Cancer chromosomal instability: therapeutic and diagnostic challenges
Nicholas McGranahan et al.
EMBO REPORTS (2012)
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Jordi Barretina et al.
NATURE (2012)
Absolute quantification of somatic DNA alterations in human cancer
Scott L. Carter et al.
NATURE BIOTECHNOLOGY (2012)
Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer
Rebecca Roylance et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2011)
Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer
Nicolai J. Birkbak et al.
CANCER RESEARCH (2011)
Chromosomal Instability Confers Intrinsic Multidrug Resistance
Alvin J. X. Lee et al.
CANCER RESEARCH (2011)
Chromosomal Instability Substantiates Poor Prognosis in Patients with Diffuse Large B-cell Lymphoma
Samuel F. Bakhoum et al.
CLINICAL CANCER RESEARCH (2011)
The aneuploidy paradox: costs and benefits of an incorrect karyotype
Jason M. Sheltzer et al.
TRENDS IN GENETICS (2011)
Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM
Charles J. Vaske et al.
BIOINFORMATICS (2010)
Mechanisms of Chromosomal Instability
Sarah L. Thompson et al.
CURRENT BIOLOGY (2010)
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
Sarah L. Thompson et al.
JOURNAL OF CELL BIOLOGY (2010)
Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage
Beatrix Bugler et al.
MOLECULAR CANCER (2010)
The PVT-1 oncogene is a myc protein target is overexpressed in transformed cells
Letizia Carramusa et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
Scott L. Carter et al.
NATURE GENETICS (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Hallmarks of 'BRCAness' in sporadic cancers
N Turner et al.
NATURE REVIEWS CANCER (2004)
KEGG: Kyoto Encyclopedia of Genes and Genomes
M Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2000)
分享论文
