Epidemiology, Risk Factors and Diagnosis of Small Bowel Adenocarcinoma

Simple Summary Small bowel adenocarcinoma is a rare tumor. Diagnosis is often obtained at an advanced stage and prognosis remains poor. The aim of this review is to report the recent epidemiological and risk factor data related to small bowel adenocarcinoma. New diagnostic tools are also described in this review. Adenocarcinomas of the small intestine are rare tumors but their incidence is increasing. There is a slight male predominance. The median age at diagnosis is the 6th decade. The most frequent primary location is the duodenum. There is no clearly identified environmental risk factor, but adenocarcinomas of the small intestine are associated in almost 20% of cases with predisposing diseases (Crohn's disease, Lynch syndrome, familial adenomatous polyposis, Peutz-Jeghers syndrome and celiac disease).

Automated summary

Small bowel adenocarcinoma is a rare tumor with increasing incidence. Diagnosis is often obtained at an advanced stage and prognosis is poor. There is no clearly identified environmental risk factor, but it is associated with certain predisposing diseases.