期刊
JOURNAL OF CLINICAL MEDICINE
卷 11, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/jcm11061498
关键词
gastric cancer; biliopancreatic reflux; gastritis; carcinoma; endoscopic surveillance; Helicobacter pylori infection; gastric stump cancer
Distal gastrectomy is a common surgical procedure for advanced gastric cancer, but it can also lead to complications such as gastric stump infection that require monitoring and treatment.
Distal gastrectomy for benign gastroduodenal peptic disease has become rare, but it still represents a widely adopted procedure for advanced and, in some countries, even for early distal gastric cancer. Survival rates following surgery for gastric malignancy are constantly improving, hence the residual mucosa of the gastric stump is exposed for a prolonged period to biliopancreatic reflux and, possibly, to Helicobacter pylori (HP) infection. Biliopancreatic reflux and HP infection are considered responsible for gastritis and metachronous carcinoma in the gastric stump after oncologic surgery. For gastrectomy patients, in addition to eradication treatment for cases that are already HP positive, endoscopic surveillance should also be recommended, for prompt surveillance and detection in the residual mucosa of any metaplastic-atrophic-dysplastic features following surgery.
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