期刊
JOURNAL OF CLINICAL MEDICINE
卷 11, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/jcm11061688
关键词
child development; anthropometrics; neurodevelopment; antenatal lifestyle intervention; routine care; obesity prevention
资金
- Else Kroner-Fresenius Foundation, Bad Homburg [5140889]
- Competence Centre for Nutrition (KErn) in Bavaria
- Bavarian State Ministry of Food, Agriculture and Forestry
- Bavarian State Ministry of Health and Care (Health Initiative Gesund.Leben.Bayern.)
- AOK Bayern
- largest statutory health insurance in Bavaria
- DEDIPAC consortium by the Joint Programming Initiative (JPI) A Healthy Diet for a Healthy Life
This study investigated the long-term effects of an antenatal lifestyle intervention on child anthropometrics and neurodevelopment up to 3 years of age. The results showed that children in the intervention group had higher scores in fine motor skills but lower scores in problem-solving skills compared to the control group.
Maternal characteristics around pregnancy may influence obesity risk and neurodevelopment in children. To date, the effect of antenatal lifestyle interventions on long-term child development is unclear. The objective was to investigate the potential long-term effects of an antenatal lifestyle intervention programme conducted alongside routine care on child anthropometrics and neurodevelopment up to 3 years of age. Mother-child pairs from the cluster-randomised GeliS trial were followed up to 3 years of age. Data on child anthropometrics in both groups were collected from routine health examinations. Neurodevelopment was assessed via questionnaire. Of the 2286 study participants, 1644 mother-child pairs were included in the analysis. Children from the intervention group were less likely to score below the cut-off in Fine motor (p = 0.002), and more likely to have a score below the cut-off in Problem-solving (p < 0.001) compared to the control group at 3 years of age. Mean weight, height, head circumference, body mass index, and the respective z-scores and percentiles were comparable between the groups at 2 and 3 years of age. We found no evidence that the lifestyle intervention affected offspring development up to 3 years of age. Further innovative intervention approaches are required to improve child health in the long-term.
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