相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer's Disease
Aneeqa Noor et al.
MOLECULAR NEUROBIOLOGY (2022)
Amyloid pathology and synaptic loss in pathological aging
Eleni Gkanatsiou et al.
JOURNAL OF NEUROCHEMISTRY (2021)
N-Truncated Aβ Starting at Position Four-Biochemical Features, Preclinical Models, and Potential as Drug Target in Alzheimer's Disease
Thomas A. Bayer
FRONTIERS IN AGING NEUROSCIENCE (2021)
N-Terminally Truncated and Pyroglutamate-Modified Aβ Forms Are Measurable in Human Cerebrospinal Fluid and Are Potential Markers of Disease Progression in Alzheimer's Disease
Guido Domingo et al.
FRONTIERS IN NEUROSCIENCE (2021)
Serum Amyloid Beta42 Is Not Eliminated by the Cirrhotic Liver: A Pilot Study
Reiner Wiest et al.
JOURNAL OF CLINICAL MEDICINE (2021)
N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer's disease
S. Zampar et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2020)
Ion channel formation by N-terminally truncated Aβ (4-42): relevance for the pathogenesis of Alzheimer's disease
Abhijith G. Karkisaval et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2020)
Liver Dysfunction as a Novel Player in Alzheimer's Progression: Looking Outside the Brain
Lisbell D. Estrada et al.
FRONTIERS IN AGING NEUROSCIENCE (2019)
The metalloprotease ADAMTS4 generates N-truncated A4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease
Susanne Walter et al.
ACTA NEUROPATHOLOGICA (2019)
Characteristics of the tissue section that influence the staining outcome in immunohistochemistry
Sylwia Libard et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2019)
Emerging roles of N- and C-terminally truncated Aβ species in Alzheimer's disease
Oliver Wirths et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2019)
A beta truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition
Erwin Cabrera et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Are N- and C-terminally truncated A species key pathological triggers in Alzheimer's disease?
Julie Dunys et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
N-truncated Aβ4-x peptides in sporadic Alzheimer's disease cases and transgenic Alzheimer mouse models
Oliver Wirths et al.
ALZHEIMERS RESEARCH & THERAPY (2017)
Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain
Norelle C. Wildburger et al.
SCIENTIFIC REPORTS (2017)
Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis
Vitaliy Ovod et al.
ALZHEIMERS & DEMENTIA (2017)
Vascular basement membranes as pathways for the passage of fluid into and out of the brain
Alan W. J. Morris et al.
ACTA NEUROPATHOLOGICA (2016)
Vascular, glial, and lymphatic immune gateways of the central nervous system
Britta Engelhardt et al.
ACTA NEUROPATHOLOGICA (2016)
Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment
Olivia A. Skrobot et al.
BRAIN (2016)
Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases
Erik N. T. P. Bakker et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2016)
Comparative pathobiology of β-amyloid and the unique susceptibility of humans to Alzheimer's disease
Rebecca F. Rosen et al.
NEUROBIOLOGY OF AGING (2016)
The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain
Silvia Fossati et al.
NEUROBIOLOGY OF DISEASE (2016)
In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein
Farron L. McIntee et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9
Mar Hernandez-Guillamon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Brain Amyloid-Beta Fragment Signatures in Pathological Ageing and Alzheimer's Disease by Hybrid Immunoprecipitation Mass Spectrometry
Erik Portelius et al.
NEURODEGENERATIVE DISEASES (2015)
Amyloid-β Efflux from the Central Nervous System into the Plasma
Kaleigh Filisa Roberts et al.
ANNALS OF NEUROLOGY (2014)
Mitochondrial dysfunction induced by a post-translationally modified amyloid linked to a familial mutation in an alternative model of neurodegeneration
Krysti Todd et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Study on Aβ34 biology and detection in transgenic mice brains
Celine Caillava et al.
NEUROBIOLOGY OF AGING (2014)
Pyroglutamate-Modified Amyloid-β Protein Demonstrates Similar Properties in an Alzheimer's Disease Familial Mutant Knock-In Mouse and Alzheimer's Disease Brain
Guoxin Wu et al.
NEURODEGENERATIVE DISEASES (2014)
The cerebrovascular basement membrane: role in the clearance of β-amyloid and cerebral amyloid angiopathy
Alan W. J. Morris et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
Yvonne Bouter et al.
ACTA NEUROPATHOLOGICA (2013)
Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome
Line De Kimpe et al.
AGE (2013)
Pyroglutamate-3 Amyloid-β Deposition in the Brains of Humans, Non-Human Primates, Canines, and Alzheimer Disease-Like Transgenic Mouse Models
Jeffrey L. Frost et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Amyloid- protein (A) Glu11 is the major -secretase site of -site amyloid- precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to A Asp1 contributes to Alzheimer pathogenesis
Yu Deng et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2013)
Oligomeric Pyroglutamate Amyloid-β is Present in Microglia and a Subfraction of Vessels in Patients with Alzheimer's Disease: Implications for Immunotherapy
Oliver Wirths et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Bradley T. Hyman et al.
ALZHEIMERS & DEMENTIA (2012)
N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation
Dagmar Schlenzig et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
Justin M. Nussbaum et al.
NATURE (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Overlapping profiles of A beta peptides in the Alzheimer's disease and pathological aging brains
Brenda D. Moore et al.
ALZHEIMERS RESEARCH & THERAPY (2012)
Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy
Cheryl A. Hawkes et al.
ACTA NEUROPATHOLOGICA (2011)
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
Berislav V. Zlokovic
NATURE REVIEWS NEUROSCIENCE (2011)
Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration
Ming Jin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease
Erik Portelius et al.
ACTA NEUROPATHOLOGICA (2010)
Iowa Variant of Familial Alzheimer's Disease Accumulation of Posttranslationally Modified A beta D23N in Parenchymal and Cerebrovascular Amyloid Deposits
Yasushi Tomidokoro et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Cerebral amyloidosis: amyloid subunits, mutants and phenotypes
A. Rostagno et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Biological markers of amyloid β-related mechanisms in Alzheimer's disease
Harald Hampel et al.
EXPERIMENTAL NEUROLOGY (2010)
Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls
S. Fossati et al.
FASEB JOURNAL (2010)
Plasma Amyloid-beta Forms in Alzheimer's Disease and Non-Alzheimer's Disease Patients
Nathalie Le Bastard et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases
Oliver Wirths et al.
JOURNAL OF NEURAL TRANSMISSION (2010)
Amyloid Efflux Transporter Expression at the Blood-Brain Barrier Declines in Normal Aging
Gerald D. Silverberg et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)
The effects of healthy aging on intracerebral blood vessels visualized by magnetic resonance angiography
Elizabeth Bullitt et al.
NEUROBIOLOGY OF AGING (2010)
Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model
Oliver Wirths et al.
ACTA NEUROPATHOLOGICA (2009)
Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
Robert D. Bell et al.
ACTA NEUROPATHOLOGICA (2009)
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
Tamas Revesz et al.
ACTA NEUROPATHOLOGICA (2009)
Tauroursodeoxycholic acid prevents E22Q Alzheimer's Aβ toxicity in human cerebral endothelial cells
R. J. S. Viana et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Clearance of Amyloid-beta Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimer's Disease
R. Deane et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2009)
Dutch and arctic mutant peptides of β amyloid1-40 differentially affect the FGF-2 pathway in brain endothelium
Raffaella Solito et al.
EXPERIMENTAL CELL RESEARCH (2009)
Preparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and function
L. M. Jungbauer et al.
JOURNAL OF MOLECULAR RECOGNITION (2009)
Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
Shaomin Li et al.
NEURON (2009)
A beta-degrading enzymes in Alzheimer's disease
James Scott Miners et al.
BRAIN PATHOLOGY (2008)
The role of the cell surface LRP and soluble LRP in blood-brain barrier a clearance in Alzheimer's Disease
R. Deane et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
Targeted proteomics in Alzheimer's disease: focus on amyloid-beta
Erik Portelius et al.
EXPERT REVIEW OF PROTEOMICS (2008)
The blood-brain barrier in health and chronic neurodegenerative disorders
Berislav V. Zlokovic
NEURON (2008)
Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease
Roy O. Weller et al.
BRAIN PATHOLOGY (2008)
Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well
William R. Brown et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2007)
Soluble protein oligomers in neurodegeneration:: lessons from the Alzheimer's amyloid β-peptide
Christian Haass et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
A beta Oligomers - a decade of discovery
Dominic M. Walsh et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives
Yan-Jiang Wang et al.
DRUG DISCOVERY TODAY (2006)
Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host
Melanie Meyer-Luehmann et al.
SCIENCE (2006)
Determination of β-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry
E Portelius et al.
JOURNAL OF PROTEOME RESEARCH (2006)
Quantification of Alzheimer pathology in ageing and dementia:: age-related accumulation of amyloid-β(42) peptide in vascular dementia
H Lewis et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2006)
Age-related microvascular degeneration in the human cerebral periventricular white matter
E Farkas et al.
ACTA NEUROPATHOLOGICA (2006)
β-amyloid is different in normal aging and in Alzheimer disease
A Piccini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Amino-truncated β-amyloid42 peptides in cerebrospinal fluid and prediction of progression of mild cognitive impairment
H Vanderstichele et al.
CLINICAL CHEMISTRY (2005)
Protein posttranslational modifications: The chemistry of proteome diversifications
CT Walsh et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions
S Schilling et al.
FEBS LETTERS (2004)
RAGE (Yin) versus LRP (Yang) balance regulates Alzheimer amyloid β-peptide clearance through transport across the blood-brain barrier
R Deane et al.
STROKE (2004)
Systemic catabolism of Alzheimer's Aβ40 and Aβ42
J Ghiso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Truncated beta-amyloid peptide species in pre-clinical Alzheimer's disease as new targets for the vaccination approach
N Sergeant et al.
JOURNAL OF NEUROCHEMISTRY (2003)
In vitro characterization of conditions for amyloid-β peptide oligomerization and fibrillogenesis
WB Stine et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The degradation of amyloid β as a therapeutic strategy in Alzheimer's disease and cerebrovascular amyloidoses
L Morelli et al.
NEUROCHEMICAL RESEARCH (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
DR Thal et al.
NEUROLOGY (2002)
Comparative analysis of an improved thioflavin-S stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections
AY Sun et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2002)
Systemic amyloid deposits in familial British dementia
JA Ghiso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Alzheimer's disease: Genes, proteins, and therapy
DJ Selkoe
PHYSIOLOGICAL REVIEWS (2001)
Clearance of Alzheimer's amyloid-β1-40 peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
M Shibata et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Evidence for seeding of β-amyloid by intracerebral infusion of Alzheimer brain extracts in β-amyloid precursor protein-transgenic mice
MD Kane et al.
JOURNAL OF NEUROSCIENCE (2000)
分享论文
