4.7 Article

Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytes

Lukas Peiffer et al.

Summary: The study found that treatment with BRAF/MEK inhibitors in melanoma patients allows for an increased expansion of pre-existing melanoma-specific T cells by inducing T-bet and TCF7.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2021)

Article Oncology

Radiomics Biomarkers Correlate with CD8 Expression and Predict Immune Signatures in Melanoma Patients

Lauren G. Aoude et al.

Summary: In the treatment of metastatic melanoma, high standard deviation or high mean of positive pixels in CT imaging were found to be associated with worse prognosis. In addition, high MPP was linked to BRAF mutation status. Immune cold signatures and CT biomarker MPP4 were also found to impact patient survival. Immunofluorescence confirmed a correlation between CD8 expression and image biomarkers.

MOLECULAR CANCER RESEARCH (2021)

Article Multidisciplinary Sciences

B cells and tertiary lymphoid structures promote immunotherapy response

Beth A. Helmink et al.

NATURE (2020)

Article Biochemical Research Methods

Comprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology

Gregor Sturm et al.

BIOINFORMATICS (2019)

Article Biochemistry & Molecular Biology

Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma

Paolo Antonio Ascierto et al.

NATURE MEDICINE (2019)

Article Medicine, General & Internal

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma

C. Robert et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Correction Immunology

The Immune Landscape of Cancer (vol 48, pg 812, 2018)

Vesteinn Thorsson et al.

IMMUNITY (2019)

Article Medicine, General & Internal

Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

J. Larkin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Immunology

Intratumoral immunoglobulin isotypes predict survival in lung adenocarcinoma subtypes

O. I. Isaeva et al.

Journal for ImmunoTherapy of Cancer (2019)

Article Multidisciplinary Sciences

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells

Caroline S. Jansen et al.

NATURE (2019)

Article Medicine, General & Internal

Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma

Alexander M. M. Eggermont et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Multidisciplinary Sciences

Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

H. Halse et al.

SCIENTIFIC REPORTS (2018)

Article Biotechnology & Applied Microbiology

SCANPY: large-scale single-cell gene expression data analysis

F. Alexander Wolf et al.

GENOME BIOLOGY (2018)

Article Biochemistry & Molecular Biology

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

Antonio Colaprico et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Multidisciplinary Sciences

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Itay Tirosh et al.

SCIENCE (2016)

Article Biotechnology & Applied Microbiology

Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Bo Li et al.

GENOME BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Genomic Classification of Cutaneous Melanoma

Rehan Akbani et al.

Article Biochemical Research Methods

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman et al.

NATURE METHODS (2015)

Article Biochemistry & Molecular Biology

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Cell Biology

Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAFV600E melanoma

Siwen Hu-Lieskovan et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Review Immunology

Tertiary lymphoid structure-associated B cells are key players in anti-tumor immunity

Claire Germain et al.

FRONTIERS IN IMMUNOLOGY (2015)

Article Statistics & Probability

Deconvolution Estimation in Measurement Error Models: TheRPackagedecon

Xiao-Feng Wang et al.

Journal of Statistical Software (2015)

Article Medicine, General & Internal

Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma

James Larkin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Immunology

Tertiary lymphoid structures in cancer and beyond

Marie-Caroline Dieu-Nosjean et al.

TRENDS IN IMMUNOLOGY (2014)

Article Biochemistry & Molecular Biology

A Landscape of Driver Mutations in Melanoma

Eran Hodis et al.

Article Statistics & Probability

Strong rules for discarding predictors in lasso-type problems

Robert Tibshirani et al.

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY (2012)

Article Oncology

The determinants of tumour immunogenicity

Thomas Blankenstein et al.

NATURE REVIEWS CANCER (2012)

Review Immunology

Standardizing immunophenotyping for the Human Immunology Project

Holden T. Maecker et al.

NATURE REVIEWS IMMUNOLOGY (2012)

Article Medicine, General & Internal

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

Paul B. Chapman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Biochemical Research Methods

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson et al.

BIOINFORMATICS (2010)

Article Biotechnology & Applied Microbiology

A scaling normalization method for differential expression analysis of RNA-seq data

Mark D. Robinson et al.

GENOME BIOLOGY (2010)

Article Multidisciplinary Sciences

Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice

Jean-David Bouaziz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Immunology

The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

Hidetoshi Sumimoto et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2006)

Article Medicine, General & Internal

Distinct sets of genetic alterations in melanoma

JA Curtin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Statistics & Probability

Regularization and variable selection via the elastic net

H Zou et al.

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY (2005)

Article Multidisciplinary Sciences

Mutations of the BRAF gene in human cancer

H Davies et al.

NATURE (2002)