Review of Open Cavity Random Lasers as Laser-Based Sensors

In this review, the concept of open cavity lasing for ultrasensitive sensing is explored, specifically in driving important innovations as laser-based biosensors???afield mostly dominatedbyfluorescence-based sensing. Laser-based sensing exhibits highersignal amplification and lower signal-to-noise ratio due to narrowemission lines as well as high sensitivity due to nonlinearcomponents. The versatility of open cavity random lasers forprobing analytes directly which is ultrasensitive to small changes inchemical composition and temperaturefluctuations paves the pathof utilizing narrow emission lines for advanced sensing. Theconcept of random lasing isfirst explained followed by acomparison of the different lasing threshold that has beenreported. This is followed by a survey of reports on laser-based sensing and more specifically as biosensors. Finally, a perspective on the way forward for open cavity laser-based sensing is put forth

Automated summary

This review explores the concept of using open cavity lasing for ultrasensitive sensing, particularly in driving important innovations in laser-based biosensors. Laser-based sensing offers higher signal amplification and lower signal-to-noise ratio compared to fluorescence-based sensing, as well as high sensitivity due to nonlinear components. The versatility of open cavity random lasers allows for direct detection of small changes in chemical composition and temperature fluctuations.