Catalyst-free decarboxylation of 4-hydroxycinnamic acids: efficient synthesis of 4-vinylphenols

We report herein an efficient protocol for the synthesis of 4-vinylphenols by a catalyst-free decarboxylation of trans-4-hydroxycinnamic acids. A variety of 4-vinylphenols has been synthesized in moderate to excellent yields. This protocol also features no polymerization.

Automated summary

We present an efficient method for synthesizing 4-vinylphenols through catalyst-free decarboxylation of trans-4-hydroxycinnamic acids. Various 4-vinylphenols have been synthesized in moderate to excellent yields using this method. This protocol also avoids polymerization.