Research Advances on Matrine

Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields.

Automated summary

Matrine, an alkaloid extracted from traditional Chinese herbs, combines the advantages of traditional herbs and chemotherapy drugs, showing distinct benefits in preventing and improving chronic diseases. Recent research has focused on its anti-atherosclerosis, anti-tumor, and anti-inflammatory properties, providing new insights for drug development in related fields.