4.6 Article

Binge eating disorder

期刊

NATURE REVIEWS DISEASE PRIMERS
卷 8, 期 1, 页码 -

出版社

NATURE PORTFOLIO
DOI: 10.1038/s41572-022-00344-y

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资金

  1. NIHR Senior Investigator Award
  2. NIMH [R01MH120170, R01MH124871, R01MH119084, R01MH118278, R01 MH124871]
  3. Brain and Behavior Research Foundation Distinguished Investigator Grant
  4. Swedish Research Council (Vetenskapsradet) [538-2013-8864]
  5. Lundbeck Foundation [R276-2018-4581]
  6. project INTERBED of the German Federal Ministry of Education and Research (Bundesministerium fur Bildung und Forschung (BMBF)) [01GV0601]
  7. PERIS [SLT006/17/00246]
  8. Instituto Salud Carlos III [PI17/01167, PI20/132]
  9. EU [728018, 847879]
  10. COST Action [CA19115]
  11. Margarete von Wrangell Program by the Federal Ministry of Science and Education Baden-Wurttemberg
  12. Federal Ministry of Education and Research (BMBF) [01KG2009]
  13. German Research Foundation (DFG) [GI 878/4-1]

向作者/读者索取更多资源

Binge eating disorder (BED) is a complex eating disorder characterized by loss of control over eating behavior and consuming large amounts of food. It is commonly associated with obesity and various somatic and mental health issues. The etiology of BED involves genetic, environmental, neuroendocrinological, and neurobiological factors. Psychotherapy is the recommended treatment, but further research and efforts are needed for prevention and improved treatment outcomes.
Binge eating disorder is an eating disorder that is characterized by loss of control of eating behaviour and episodes of eating very large amounts of food. This Primer discusses the epidemiology, mechanisms, diagnosis and treatment of binge eating disorder. Binge eating disorder (BED) is characterized by regular binge eating episodes during which individuals ingest comparably large amounts of food and experience loss of control over their eating behaviour. The worldwide prevalence of BED for the years 2018-2020 is estimated to be 0.6-1.8% in adult women and 0.3-0.7% in adult men. BED is commonly associated with obesity and with somatic and mental health comorbidities. People with BED experience considerable burden and impairments in quality of life, and, at the same time, BED often goes undetected and untreated. The aetiology of BED is complex, including genetic and environmental factors as well as neuroendocrinological and neurobiological contributions. Neurobiological findings highlight impairments in reward processing, inhibitory control and emotion regulation in people with BED, and these neurobiological domains are targets for emerging treatment approaches. Psychotherapy is the first-line treatment for BED. Recognition and research on BED has increased since its inclusion into DSM-5; however, continuing efforts are needed to understand underlying mechanisms of BED and to improve prevention and treatment outcomes for this disorder. These efforts should also include screening, identification and implementation of evidence-based interventions in routine clinical practice settings such as primary care and mental health outpatient clinics.

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