Making sense of BMP signaling complexity

Cellular signaling systems are immensely complex. Dedicated experimental and theoretical approaches are therefore required to decipher how they function. In this issue of Cell Systems, two studies systematically interrogate the Bone Morphogenetic Protein (BMP) pathway, uncovering mechanisms and consequences of distinct responses to combinations of BMP ligands.

Automated summary

This article discusses the complexity of cellular signaling systems and examines the mechanisms and consequences of different responses to combinations of BMP ligands in the BMP pathway.