期刊
INFLAMMOPHARMACOLOGY
卷 30, 期 2, 页码 397-434出版社
SPRINGER BASEL AG
DOI: 10.1007/s10787-022-00931-1
关键词
Ulcerative colitis; Herbal constituents; Anti-ulcerogenic activity; Inflammatory bowel disease
Ulcerative colitis (UC) is a chronic inflammatory bowel disease with unknown cause. Conventional treatments for UC have limitations and side effects. Natural remedies, with comparatively fewer side effects, have been used for centuries. This review explores the role of herbal drugs, such as gymnemic acid, shagoal, catechin, curcumin, arctigenin, and boswellic acid, in the treatment of UC. Further research is needed to establish the clinical usefulness and molecular mechanisms of these natural products.
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology. Several conventional treatments for UC such as corticosteroids, immunosuppressive agents, tumor necrosis factor antagonist, integrin blockers, and interleukin antagonist, and salicylates are available but are associated with the various limitations and side-effects. None of the above treatments helps to achieve the ultimate goal of the therapy, i.e., maintenance of remission in the long-term. Natural remedies for the treatment of UC show comparatively less side effects as compared to conventional approaches, and affordable. The current review presents details on the role of herbal drugs in the treatment and cure of UC. Google, PubMed, Web of Science, and Scopus portals have been searched for potentially relevant literature to get the latest developments and updated information related to use of natural drugs in the treatment of UC. Natural products have been used over centuries to treat UC. Some of the essential herbal constituents exhibiting antiulcerogenic activity include gymnemic acid (Gymnema sylvestre), shagoal (Zingiber officinale), catechin (Camellia sinensis), curcumin (Curcuma longa), arctigenin (Arctium lappa), and boswellic acid (Boswellia serrata). Although many plant-derived products have been recommended for UC, further research to understand the exact molecular mechanism is still warranted to establish their usefulness clinically.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据