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E Wolf et al.
DRUG DISCOVERY TODAY (2005)
Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector
J Jakobsson et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Stability improvement of antibodies for extracellular and intracellular applications:: CDR grafting to stable frameworks and structure-based framework engineering
S Ewert et al.
METHODS (2004)
Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)
SP Persengiev et al.
RNA (2004)
Differential transgene expression in brain cells in vivo and in vitro from AAV-2 vectors with small transcriptional control units
S Kügler et al.
VIROLOGY (2003)
Expression profiling reveals off-target gene regulation by RNAi
AL Jackson et al.
NATURE BIOTECHNOLOGY (2003)
Immunomodulation of enzyme function in plants by single-domain antibody fragments
SA Jobling et al.
NATURE BIOTECHNOLOGY (2003)
Engineered antibodies
Peter J. Hudson et al.
NATURE MEDICINE (2003)
Minocycline and other tetracycline derivatives: A neuroprotective strategy in Parkinson's disease and Huntington's disease
M Thomas et al.
CLINICAL NEUROPHARMACOLOGY (2003)
Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus
D Favre et al.
JOURNAL OF VIROLOGY (2002)
Gene transfer of a chimeric trans-activator is immunogenic and results in short-lived transgene expression
M Latta-Mahieu et al.
HUMAN GENE THERAPY (2002)
Therapeutic applications of monoclonal antibodies
M Berger et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2002)
Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury
KL Arvin et al.
ANNALS OF NEUROLOGY (2002)
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
S Zhu et al.
NATURE (2002)
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
DC Wu et al.
JOURNAL OF NEUROSCIENCE (2002)
Antisense therapy in oncology:: new hope for an old idea?
I Tamm et al.
LANCET (2001)
The risk of liver damage associated with minocycline: A comparative study
HE Seaman et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2001)
Rapid transferrin efflux from brain to blood across the blood-brain barrier
Y Zhang et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Mediated efflux of IgG molecules from brain to blood across the blood-brain barrier
Y Zhang et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
Selective rep-cap gene amplification as a mechanism for high-titer recombinant AAV production from stable cell lines
XL Liu et al.
MOLECULAR THERAPY (2000)
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
M Chen et al.
NATURE MEDICINE (2000)
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