相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Helios is a marker, not a driver, of human Treg stability
Avery J. Lam et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2022)
Novel delivery of cellular therapy to reduce ischemia reperfusion injury in kidney transplantation
Emily R. Thompson et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2021)
Mesenchymal stromal cell treatment of donor kidneys during ex vivo normothermic machine perfusion: A porcine renal autotransplantation study
Stine Lohmann et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2021)
Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients
Paul N. Harden et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2021)
Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction
Baptiste Lamarthee et al.
NATURE COMMUNICATIONS (2021)
Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications
Leila Amini et al.
FRONTIERS IN IMMUNOLOGY (2021)
Freezing Medium Containing 5% DMSO Enhances the Cell Viability and Recovery Rate After Cryopreservation of Regulatory T Cell Products ex vivo and in vivo
Daniel Kaiser et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Strong Expansion of Human Regulatory T Cells for Adoptive Cell Therapy Results in Epigenetic Changes Which May Impact Their Survival and Function
Kristy Ou et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Ex-vivo Kidney Machine Perfusion: Therapeutic Potential
Ruta Zulpaite et al.
FRONTIERS IN MEDICINE (2021)
Antigen-Specific Regulatory T Cell Therapy in Autoimmune Diseases and Transplantation
Claudia Selck et al.
FRONTIERS IN IMMUNOLOGY (2021)
Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation
Alberto Sanchez-Fueyo et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2020)
Discrepancy analysis comparing molecular and histology diagnoses in kidney transplant biopsies
Katelynn Madill-Thomsen et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2020)
Regulatory T Cells and Human Disease
Shimon Sakaguchi et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 38 (2020)
Control of regulatory T-cell differentiation and function by T-cell receptor signalling and Foxp3 transcription factor complexes
Masahiro Ono
IMMUNOLOGY (2020)
Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases
Naganari Ohkura et al.
CELL RESEARCH (2020)
Autoantigen specific IL-2 activated CD4+ CD25+T regulatory cells inhibit induction of experimental autoimmune neuritis
Giang T. Tran et al.
JOURNAL OF NEUROIMMUNOLOGY (2020)
Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials
Birgit Sawitzki et al.
LANCET (2020)
The Regulatory Effects of mTOR Complexes in the Differentiation and Function of CD4+ T Cell Subsets
Peng Wang et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2020)
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells
M. Goodwin et al.
SCIENCE ADVANCES (2020)
Distinct metabolic pathways mediate regulatory T cell differentiation and function
Hisashi Hashimoto et al.
IMMUNOLOGY LETTERS (2020)
Treating Ischemically Damaged Porcine Kidneys with Human Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stromal Cells During Ex Vivo Normothermic Machine Perfusion
Merel B. F. Pool et al.
STEM CELLS AND DEVELOPMENT (2020)
Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial
Andy Roemhild et al.
BMJ-BRITISH MEDICAL JOURNAL (2020)
T-reg cell-based therapies: challenges and perspectives
Caroline Raffin et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Potentiating Renal Regeneration Using Mesenchymal Stem Cells
Lauren Brasile et al.
TRANSPLANTATION (2019)
Convergence of Cell Pharmacology and Drug Delivery
Ayesha Aijaz et al.
STEM CELLS TRANSLATIONAL MEDICINE (2019)
Infusing Mesenchymal Stromal Cells into Porcine Kidneys during Normothermic Machine Perfusion: Intact MSCs Can Be Traced and Localised to Glomeruli
Merel Pool et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Mesenchymal Stromal Cells Are Retained in the Renal Cortex Independently of Their Metabolic State After Renal Intra-Arterial Infusion
Jesus M. Sierra-Parraga et al.
STEM CELLS AND DEVELOPMENT (2019)
Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19
Masahiko Akamatsu et al.
SCIENCE IMMUNOLOGY (2019)
Helios+ and Helios- Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires
Angela M. Thornton et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2019)
Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol
Katherine N. Macdonald et al.
CYTOTHERAPY (2019)
mTOR Inhibitor Everolimus in Regulatory T Cell Expansion for Clinical Application in Transplantation
Roberto Gedaly et al.
TRANSPLANTATION (2019)
Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection
Elodie Picarda et al.
CELL REPORTS (2019)
Liver homing of clinical grade Tregs after therapeutic infusion in patients with autoimmune hepatitis
Ye Htun Oo et al.
JHEP REPORTS (2019)
Human CD8+ Tregs expressing a MHC-specific CAR display enhanced suppression of human skin rejection and GVHD in NSG mice
Severine Bezie et al.
BLOOD ADVANCES (2019)
Engineering universal cells that evade immune detection
Robert Lanza et al.
NATURE REVIEWS IMMUNOLOGY (2019)
Engineered MBP-specific human Tregs ameliorate MOG-induced EAE through IL-2-triggered inhibition of effector T cells
Yong Chan Kim et al.
JOURNAL OF AUTOIMMUNITY (2018)
Targeting Antigen-Specific B Cells Using Antigen-Expressing Transduced Regulatory T Cells
Ai-Hong Zhang et al.
JOURNAL OF IMMUNOLOGY (2018)
A Phase I Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants
James M. Mathew et al.
SCIENTIFIC REPORTS (2018)
Critical Role of TGE-beta and IL-2 Receptor Signalling in Foxp3 Inducion by an Inhibitor of DNA Methylation
Kristin Freudenberg et al.
FRONTIERS IN IMMUNOLOGY (2018)
The Pharmacology of T Cell Therapies
Michael C. Milone et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2018)
A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials
Henrieta Fraser et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2018)
Industrializing Autologous Adoptive Immunotherapies: Manufacturing Advances and Challenges
Rohin K. Iyer et al.
FRONTIERS IN MEDICINE (2018)
mTOR Regulation of Glycolytic Metabolism in T Cells
Robert J. Salmond
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)
Generation of human islet-specific regulatory T cells by TCR gene transfer
Caroline M. Hull et al.
JOURNAL OF AUTOIMMUNITY (2017)
Cell-Free DNA and Active Rejection in Kidney Allografts
Roy D. Bloom et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
Biomechanical properties of human T cells in the process of activation based on diametric compression by micromanipulation
Mingming Du et al.
MEDICAL ENGINEERING & PHYSICS (2017)
Harnessing Advances in T Regulatory Cell Biology for Cellular Therapy in Transplantation
Avery J. Lam et al.
TRANSPLANTATION (2017)
CD45RA Distinguishes CD4+CD25+CD127-/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression
Rebeca Arroyo Hornero et al.
TRANSPLANTATION (2017)
Avidity and Bystander Suppressive Capacity of Human Regulatory T Cell Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes
Wen-I Yeh et al.
FRONTIERS IN IMMUNOLOGY (2017)
Safety of Intra-Arterial Injection With Tumor-Activated T Cells to the Rabbit Brain Evaluated by MRI and SPECT/CT
Johan Lundberg et al.
CELL TRANSPLANTATION (2017)
Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants
S. Chandran et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2017)
Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection
D. A. Boardman et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2017)
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
James B. Canavan et al.
GUT (2016)
Acute Rejection Rates and Graft Outcomes According to Induction Regimen among Recipients of Kidneys from Deceased Donors Treated with Tacrolimus and Mycophenolate
Bekir Tanriover et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
A Pilot Study of Operational Tolerance With a Regulatory T-cell-Based Cell Therapy in Living Donor Liver Transplantation
Satoru Todo et al.
HEPATOLOGY (2016)
Role of Metabolism in the Immunobiology of Regulatory T Cells
Mario Galgani et al.
JOURNAL OF IMMUNOLOGY (2016)
Intrahepatic mRNA Expression of FAS, FASL, and FOXP3 Genes Is Associated with the Pathophysiology of Chronic HCV Infection
Ednelza da Silva Graca Amoras et al.
PLOS ONE (2016)
Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity
Hidetoshi Nakagawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Coexpression of TIGIT and FCRL3 Identifies Helios(+) Human Memory Regulatory T Cells
Khalid Bin Dhuban et al.
JOURNAL OF IMMUNOLOGY (2015)
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex
Dennis X. Beringer et al.
NATURE IMMUNOLOGY (2015)
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
Jeffrey A. Bluestone et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses
Yong Chan Kim et al.
BLOOD (2015)
Cellular Size as a Means of Tracking mTOR Activity and Cell Fate of CD4+T Cells upon Antigen Recognition
Kristen N. Pollizzi et al.
PLOS ONE (2015)
Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4+Foxp3+ Regulatory T Cells
Edyta Szurek et al.
PLOS ONE (2015)
Superiority of Rapamycin Over Tacrolimus in Preserving Nonhuman Primate Treg Half-Life and Phenotype After Adoptive Transfer
K. Singh et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2014)
Mesenchymal stromal cells reset the scatter factor system and cytokine network in experimental kidney transplantation
Marilena Gregorini et al.
BMC IMMUNOLOGY (2014)
MHC-derived allopeptide activates TCR-biased CD8+ Tregs and suppresses organ rejection
Elodie Picarda et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Suppression of Murine Colitis and its Associated Cancer by Carcinoembryonic Antigen-Specific Regulatory T Cells
Dan Blat et al.
MOLECULAR THERAPY (2014)
Challenges in cryopreservation of regulatory T cells (Tregs) for clinical therapeutic applications
Karolina Golab et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2013)
Comment on Helios- and Helios- Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans
Maha Ayyoub et al.
JOURNAL OF IMMUNOLOGY (2013)
Response to Comment on Helios+ and Helios- Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans
Katherine G. MacDonald et al.
JOURNAL OF IMMUNOLOGY (2013)
Helios+ and Helios- Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans
Megan E. Himmel et al.
JOURNAL OF IMMUNOLOGY (2013)
Chimeric Antigen Receptor-Modified T Cells for Acute Lymphoid Leukemia
Stephan A. Grupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
Tomoyuki Yamaguchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer
Laura Passerini et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
Renier J. Brentjens et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
The Basic Principles of Chimeric Antigen Receptor Design
Michel Sadelain et al.
CANCER DISCOVERY (2013)
TCR affinity and specificity requirements for human regulatory T-cell function
Gabriela Plesa et al.
BLOOD (2012)
Cryopreservation modulates the detection of regulatory T cell markers
Sebastian Sattui et al.
CYTOMETRY PART B-CLINICAL CYTOMETRY (2012)
T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
Naganari Ohkura et al.
IMMUNITY (2012)
The regulatory/cytotoxic infiltrating T cells in early renal surveillance biopsies predicts acute rejection and survival
Ying Xu et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)
Stem cell therapy in ischemic stroke Role of IV and intra-arterial therapy
Vivek Misra et al.
NEUROLOGY (2012)
The Time Is Crucial for Ex Vivo Expansion of T Regulatory Cells for Therapy
Natalia Marek et al.
CELL TRANSPLANTATION (2011)
Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells
Eleonora Tresoldi et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)
Regulatory T cells and IL-17-producing cells in graft-versus-host disease
Takanori Teshima et al.
IMMUNOTHERAPY (2011)
Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
Ryan D. Michalek et al.
JOURNAL OF IMMUNOLOGY (2011)
Foxp3 Expression in Liver Correlates with the Degree but Not the Cause of Inflammation
Matthaios Speletas et al.
MEDIATORS OF INFLAMMATION (2011)
Chimeric Antigen Receptor-Modified T Cells in Chronic Lymphoid Leukemia
David L. Porter et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity
Keli L. Hippen et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells
Pervinder Sagoo et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
James N. Kochenderfer et al.
BLOOD (2010)
Inflammation and the balance of Treg and Th17 cells in transplant rejection and tolerance
Dusan Hanidziar et al.
CURRENT OPINION IN ORGAN TRANSPLANTATION (2010)
Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study
Lian Li et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2010)
Cryopreservation does not alter the frequency of regulatory T cells in peripheral blood mononuclear cells
D. Van Hemelen et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2010)
Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3(+) T Regulatory Cells
Angela M. Thornton et al.
JOURNAL OF IMMUNOLOGY (2010)
Ex Vivo Expansion of CD4(+)CD25(+) T Regulatory Cells for Immunosuppressive Therapy
Piotr Trzonkowski et al.
CYTOMETRY PART A (2009)
Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg
Leigh A. Stephens et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
Makoto Miyara et al.
IMMUNITY (2009)
Epigenetic Control
Genevieve P. Delcuve et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation
Eyad Elkord
JOURNAL OF IMMUNOLOGICAL METHODS (2009)
FOXP3-enriched infiltrates associated with better outcome in renal allografts with inflamed fibrosis
Julien Zuber et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)
Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect
Uwe M. Fischer et al.
STEM CELLS AND DEVELOPMENT (2009)
FOXP3 expression in human kidney transplant biopsies is associated with rejection and time post transplant but not with favorable outcomes
S. Bunnag et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2008)
Forced overexpression of either of the two common human Foxp3 isoforms can induce regulatory T cells from CD4+CD25- cells
Tineke Aarts-Riemens et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Redirection of regulatory T cells with predetermined specificity for the treatment of experimental colitis in mice
Eran Elinav et al.
GASTROENTEROLOGY (2008)
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
Sokol Haxhinasto et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Presence of FoxP3+ regulatory T cells predicts outcome of subclinical rejection of renal allografts
Oriol Bestard et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Intragraft Levels of Foxp3 mRNA Predict Progression in Renal Transplants with Borderline Change
Hicham Mansour et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127pos Depletion, Treg Expansion, and Treg Cryopreservation
Jorieke H. Peters et al.
PLOS ONE (2008)
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
Stephan Sauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Achieving donor-specific hyporesponsiveness is associated with FOXP3+ regulatory T cell recruitment in human renal allograft infiltrates
Oriol Bestard et al.
JOURNAL OF IMMUNOLOGY (2007)
Stem cell transplantation: The lung barrier
S. Schrepfer et al.
TRANSPLANTATION PROCEEDINGS (2007)
The regulatory/cytotoxic graft-infiltrating T cells differentiate renal allograft borderline change from acute rejection
Philippe Grimbert et al.
TRANSPLANTATION (2007)
Pathological and clinical correlates of FOXP3(+) cells in renal allografts during acute rejection
F. Veronese et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2007)
Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion
Petra Hoffmann et al.
BLOOD (2006)
Gene therapy of arthritis with TCR isolated from the inflamed paw
Keishi Fujio et al.
JOURNAL OF IMMUNOLOGY (2006)
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
Yisong Y. Wan et al.
NATURE IMMUNOLOGY (2006)
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
Weihong Liu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
Nabila Seddiki et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Low circulating regulatory T-cell levels after acute rejection in liver transplantation
A Demirkiran et al.
LIVER TRANSPLANTATION (2006)
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
M Battaglia et al.
BLOOD (2005)
Analyses of peripheral blood mononuclear cells in operational tolerance after pediatric living donor liver transplantation
Y Li et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2004)
Direct vascular delivery of primitive hematopoletic cells to bone marrow improves localization but not engraftment
KT Chabner et al.
BLOOD (2004)
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
QZ Tang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Identification of regulatory T cells in tolerated allografts
L Graca et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
IL-7 enhances the survival and maintains the size of naive T cells
JC Rathmell et al.
JOURNAL OF IMMUNOLOGY (2001)
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
ME Brunkow et al.
NATURE GENETICS (2001)
The dynamic in vivo distribution of bone marrow-derived mesenchymal stent cells after infusion
JZ Gao et al.
CELLS TISSUES ORGANS (2001)
分享论文
