4.6 Article

Trypsin Depolarizes Pacemaker Potentials in Murine Small Intestinal Interstitial Cells of Cajal

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Effects of black garlic on the pacemaker potentials of interstitial cells of Cajal in murine small intestine in vitro and on gastrointestinal motility in vivo

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Summary: This study investigated the effects of black garlic extract on pacemaker potentials of ICC in the small intestines of mice and its potential to regulate gastrointestinal motility. The study also explored the antioxidant activity of black garlic extract. The results showed that black garlic extract depolarizes the pacemaker potentials of ICC and increases the intestinal transit rate. Additionally, black garlic extract exhibited antioxidant activity.

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