4.8 Article

In Situ Detection of Kidney Organoid Generation From Stem Cells Using a Simple Electrochemical Method

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell & Tissue Engineering

Electrospinning Fabrication Methods to Incorporate Laminin in Polycaprolactone for Kidney Tissue Engineering

Busra Baskapan et al.

Summary: Current treatment options for renal diseases are insufficient, prompting the exploration of tissue engineering as a new approach. This study investigates the incorporation of laminin into polycaprolactone electrospun scaffolds, demonstrating the importance of hybrid scaffolds for kidney tissue engineering.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2022)

Article Urology & Nephrology

Human kidney organoids produce functional renin

Anusha S. Shankar et al.

Summary: This study used human induced pluripotent stem cell-derived kidney organoids as a model to investigate the role of renin and the renin-angiotensin system in the kidney, demonstrating the expression of renin in kidney organoids and providing insights into their endocrine potential.

KIDNEY INTERNATIONAL (2021)

Article Chemistry, Multidisciplinary

A Spheroid-Forming Hybrid Gold Nanostructure Platform That Electrochemically Detects Anticancer Effects of Curcumin in a Multicellular Brain Cancer Model

Intan Rosalina Suhito et al.

Summary: This study introduces a multifunctional platform for efficient formation of 3D multicellular cancer spheroids and real-time assessment of the anticancer effects of curcumin in a brain tumor coculture model. By using electrochemical signals, the platform enables precise evaluation of potential anticancer compounds on cocultured spheroids without damaging their structure. The hybrid platform proves to be a highly promising and high-throughput tool for drug screening based on 3D cell cultivation.
Article Chemistry, Physical

Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

Kynan T. Lawlor et al.

Summary: The study demonstrates the use of extrusion-based three-dimensional cellular bioprinting to rapidly and efficiently generate kidney organoids with highly reproducible cell number and viability. This technology not only improves throughput and quality control in organoid production, but also facilitates precise control of structure, enhancing the in vitro and in vivo applications of stem cell-derived human kidney tissue.

NATURE MATERIALS (2021)

Article Multidisciplinary Sciences

A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo

J. O. R. Hernandez et al.

Summary: The lack of animal models for certain human diseases hinders the understanding of disease mechanisms and the testing of potential therapies in vivo. This study presents an innovative tissue bioengineering strategy using patient-derived hiPSCs for modeling a rare kidney tumor called angiomyolipoma, both in vitro and in vivo.

NATURE COMMUNICATIONS (2021)

Article Nanoscience & Nanotechnology

Effect of biochemical and biomechanical factors on vascularization of kidney organoid-on-a-chip

Han Na Lee et al.

Summary: By mimicking shear stress fluid flow and optimizing extracellular matrix conditions, our kidney organoid-on-a-chip system showed more mature podocytes and vascular structures compared to static culture, with increased sensitivity to nephrotoxic drugs. Physiological flow was demonstrated to play a crucial role in maintaining various physiological functions of kidney organoids.

NANO CONVERGENCE (2021)

Review Cell Biology

Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities

Melissa C. Stein et al.

Summary: Kidney diseases are significant causes of morbidity and mortality globally, with immune-mediated mechanisms playing a crucial role. Current understanding of many kidney diseases is limited, but the development of organoid models provides new opportunities to study the interactions between renal cells and immune cells in disease pathogenesis.

CELL AND TISSUE RESEARCH (2021)

Review Cell & Tissue Engineering

Liver Organoids: Formation Strategies and Biomedical Applications

Xinglong Zhu et al.

Summary: Liver organoid technology is effective in studying the structural and physiological characteristics of liver tissue, and shows promise in regenerative medicine, disease modeling, drug screening, and personalized treatment. Liver organoids are a promising in vitro model for basic research and the development of clinical therapeutic interventions for liver diseases.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2021)

Article Multidisciplinary Sciences

Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

Zipeng Zeng et al.

Summary: Researchers have developed a model to study the collecting duct system in kidneys by generating organoids from ureteric bud (UB) progenitor cells derived from mouse and human primary tissues, as well as from hESC and hiPSC, showing potential for modeling congenital anomalies of the kidney and urinary tract.

NATURE COMMUNICATIONS (2021)

Article Cell Biology

Perspective: Extending the Utility of Three-Dimensional Organoids by Tissue Clearing Technologies

Etsuo A. Susaki et al.

Summary: Organoids, developed from stem cells, exhibit a miniaturized 3D structure and part of the functions of original organs, replacing real organs for various research purposes. Recent tissue clearing and 3D imaging techniques allow for comprehensive analysis and examination of organoids, enhancing their utility in basic biology and clinical applications such as organoid production and drug screening.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Review Nanoscience & Nanotechnology

Organ-on-a-chip technology for nanoparticle research

Shawn Kang et al.

Summary: The field of nanoengineering and nanomedicine has experienced explosive growth in the last two decades, with engineered nanoparticles garnering great attention. Researchers are focusing on developing new technologies to simulate and analyze the efficacy and safety of nanotherapeutics in human physiological systems in vitro. Organ-on-a-chip technology represents the latest advance in addressing the limitations of conventional preclinical models.

NANO CONVERGENCE (2021)

Review Urology & Nephrology

Studying Kidney Diseases at the Single-Cell Level

Mengmeng Jiang et al.

Summary: Our understanding of kidney disease pathogenesis is limited by the incomplete molecular characterization of cell types responsible for kidney functions. Application of single-cell technologies for the study of the kidney has revealed cellular heterogeneity, gene expression signatures, and molecular dynamics during the onset and development of kidney diseases. Single-cell analyses of kidney organoids and allograft tissues offer new insights into kidney organogenesis, disease mechanisms, and therapeutic outcomes.

KIDNEY DISEASES (2021)

Review Anatomy & Morphology

Kidney organoids in translational medicine: Disease modeling and regenerative medicine

Tomoya Miyoshi et al.

DEVELOPMENTAL DYNAMICS (2020)

Review Biochemical Research Methods

3D Pancreatic Tissue Modeling in vitro: Advances and Prospects

Myungji Kim et al.

BIOCHIP JOURNAL (2020)

Article Multidisciplinary Sciences

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

Camilla Calandrini et al.

NATURE COMMUNICATIONS (2020)

Editorial Material Urology & Nephrology

Organoid models of childhood kidney tumours

Ariadne H. A. G. Ooms et al.

NATURE REVIEWS UROLOGY (2020)

Article Cell & Tissue Engineering

Overcoming kidney organoid challenges for regenerative medicine

Thomas Geuens et al.

NPJ REGENERATIVE MEDICINE (2020)

Article Biology

Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids

Ashwani Kumar Gupta et al.

COMMUNICATIONS BIOLOGY (2020)

Article Neurosciences

Convolutional Neural Networks Can Predict Retinal Differentiation in Retinal Organoids

Evgenii Kegeles et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2020)

Review Physiology

Kidney Organoids as Disease Models: Strengths, Weaknesses and Perspectives

Ricardo Romero-Guevara et al.

FRONTIERS IN PHYSIOLOGY (2020)

Article Chemistry, Analytical

Rapid and sensitive electrochemical detection of anticancer effects of curcumin on human glioblastoma cells

Intan Rosalina Suhito et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Article Cell & Tissue Engineering

Induced Intermediate Mesoderm Combined with Decellularized Kidney Scaffolds for Functional Engineering Kidney

Jianye Zhang et al.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2019)

Article Multidisciplinary Sciences

Organoid culture media formulated with growth factors of defined cellular activity

Manuela Urbischek et al.

SCIENTIFIC REPORTS (2019)

Review Urology & Nephrology

Human kidney organoids: progress and remaining challenges

Ryuichi Nishinakamura

NATURE REVIEWS NEPHROLOGY (2019)

Article Multidisciplinary Sciences

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

Ayshwarya Subramanian et al.

NATURE COMMUNICATIONS (2019)

Article Biochemical Research Methods

Evaluation of variability in human kidney organoids

Belinda Phipson et al.

NATURE METHODS (2019)

Article Genetics & Heredity

Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

Alexander N. Combes et al.

GENOME MEDICINE (2019)

Article Medicine, Research & Experimental

Organoid single cell profiling identifies a transcriptional signature of glomerular disease

Jennifer L. Harder et al.

JCI INSIGHT (2019)

Article Urology & Nephrology

Impact of chronic kidney disease on mortality: A nationwide cohort study

Kyeong Min Kim et al.

KIDNEY RESEARCH AND CLINICAL PRACTICE (2019)

Article Cell & Tissue Engineering

Role of the Extracellular Matrix in Stem Cell Maintenance

Ana Pardo-Saganta et al.

CURRENT STEM CELL REPORTS (2019)

Article Public, Environmental & Occupational Health

The global burden of kidney disease and the sustainable development goals

Valerie A. Luyckx et al.

BULLETIN OF THE WORLD HEALTH ORGANIZATION (2018)

Editorial Material Cell & Tissue Engineering

Understanding the Extracellular Matrix to Enhance Stem Cell-Based Tissue Regeneration

Laura E. Niklason

CELL STEM CELL (2018)

Editorial Material Biochemical Research Methods

Organoids

Natalie de Souza

NATURE METHODS (2018)

Review Medicine, General & Internal

Applications of kidney organoids derived from human pluripotent stem cells

Yong Kyun Kim et al.

KOREAN JOURNAL OF INTERNAL MEDICINE (2018)

Review Genetics & Heredity

Progress and potential in organoid research

Giuliana Rossi et al.

NATURE REVIEWS GENETICS (2018)

Article Biochemical Research Methods

Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells

Ryuji Morizane et al.

NATURE PROTOCOLS (2017)

Review Biochemistry & Molecular Biology

Modeling Development and Disease with Organoids

Hans Clevers

Article Biochemical Research Methods

Generation of kidney organoids from human pluripotent stem cells

Minoru Takasato et al.

NATURE PROTOCOLS (2016)

Article Biotechnology & Applied Microbiology

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

Ryuji Morizane et al.

NATURE BIOTECHNOLOGY (2015)

Article Multidisciplinary Sciences

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

Benjamin S. Freedman et al.

NATURE COMMUNICATIONS (2015)