4.6 Article

Association between laryngopharyngeal reflux and obstructive sleep apnea in adults

期刊

PEERJ
卷 10, 期 -, 页码 -

出版社

PEERJ INC
DOI: 10.7717/peerj.13303

关键词

Laryngopharyngeal reflux; LPR; Obstructive sleep apnea; OSA

资金

  1. Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Indonesia
  2. Department of Nutrition, Faculty of Medicine, University of Indonesia

向作者/读者索取更多资源

This study aimed to investigate the relationship between laryngopharyngeal reflux (LPR) and obstructive sleep apnea syndrome (OSAS). The results showed that the BMI of the OSAS group was significantly higher than the non-OSAS group, but there were no significant differences in reflux symptom index (RSI) and reflux finding score (RFS) between the two groups. There was also no significant correlation between RSI/RFS and AHI (apnea-hypopnea index).
Background. Obstructive sleep apnea syndrome (OSAS) and laryngopharyngeal reflux (LPR) have been found to coexist in the population. OSAS and LPR also share obesity as an important risk factor. However, the relationship between LPR and OSAS remains unclear. This study aimed to correlate LPR as measured by the Reflux Symptom Index (RSI) and the Reflux Finding Score (RFS) with OSAS. Methods. This cross-sectional study included sixty-four subjects who underwent anamnesis to complete the RSI and the Epworth Sleeping Scale (ESS). The subjects were then divided into the OSAS and non-OSAS groups based on the Apnea-Hypopnea Index (AHI) obtained through a polysomnography examination. Both groups underwent a flexible fiberoptic nasopharyngolaryngoscopy examination to determine the RFS. LPR was identified based on the RSI and RFS. Results. The mean BMI of the OSAS group significantly was higher than the non-OSAS group (p < 0.05). Most of the subjects in the OSAS group exhibited mild-moderate OSAS (AHI 10-29), and severe OSAS occurred in only seven subjects. The mean RSI and RFS values in the OSAS group did not differ significantly from the non-OSAS group (p = 0.34 and p = 0.36, respectively). The proportion of LPR between the mild-moderate OSAS group, the severe OSAS group, and the non-OSAS group did not differ significantly (p = 1.00). RSI and RFS did not significantly correlate with AHI. Based on RSI, the proportion of LPR between the ESS (+) and ESS (-) groups did not significantly differ (adjusted p = 0.062). The proportion of LPR based on RFS was almost equal between the ESS (+) and ESS (-) groups (p = 0.817). Conclusions. The BMI of the OSAS group was significantly higher than the non-OSAS group. There was no significant difference in RSI and RFS between the OSAS and nonOSAS groups. There was no significant correlation between RSI and AHI, or between RFS and AHI. There was no significant difference in the proportion of RSI between the ESS (+) and the ESS (-) groups.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据