Graphene Biosensors-A Molecular Approach

Graphene is the material elected to study molecules and monolayers at the molecular scale due to its chemical stability and electrical properties. The invention of scanning tunneling microscopy has deepened our knowledge on molecular systems through imaging at an atomic resolution, and new possibilities have been investigated at this scale. Interest on studies on biomolecules has been demonstrated due to the possibility of mimicking biological systems, providing several applications in nanomedicine: drug delivery systems, biosensors, nanostructured scaffolds, and biodevices. A breakthrough came with the synthesis of molecular systems by stepwise methods with control at the atomic/molecular level. This article presents a review on self-assembled monolayers of biomolecules on top of graphite with applications in biodevices. Special attention is given to porphyrin systems adsorbed on top of graphite that are able to anchor other biomolecules.

Automated summary

Graphene has been chosen as the material to study molecules and monolayers due to its stability and electrical properties. The invention of scanning tunneling microscopy has deepened our understanding of molecular systems and opened up new possibilities at the atomic scale. Research on biomolecules has gained interest, as they can mimic biological systems and have applications in nanomedicine. By synthesizing molecular systems with control at the atomic/molecular level, breakthroughs have been made in the application of self-assembled monolayers of biomolecules on graphite surfaces, especially the porphyrin systems that can anchor other biomolecules.