4.6 Article

A Novel Organ-Specific Approach to Selectively Target Sensory Afferents Innervating the Aortic Arch

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cardiac & Cardiovascular Systems

Targeting angiotensin type-2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice

Mazher Mohammed et al.

Summary: These studies use advanced techniques to investigate the role of AT2R-expressing neurons in the NTS in blood pressure regulation. Optogenetic stimulation of these neurons increases GABA release and blood pressure. Central activation of AT2R also reduces GABA-related gene expression and blunts pressor responses.

CARDIOVASCULAR RESEARCH (2022)

Article Neurosciences

An Angiotensin-Responsive Connection from the Lamina Terminalis to the Paraventricular Nucleus of the Hypothalamus Evokes Vasopressin Secretion to Increase Blood Pressure in Mice

Charles J. Frazier et al.

Summary: The study shows that AT1aR neurons in the lamina terminalis play a crucial role in blood pressure control by influencing cardiovascular parameters and fluid intake through optogenetic stimulation. Additionally, activation of these neurons leads to neuroendocrine and behavioral responses that increase blood pressure.

JOURNAL OF NEUROSCIENCE (2021)

Article Biology

Control of feeding by Piezo-mediated gut mechanosensation in Drosophila

Soohong Min et al.

Summary: The study reveals the essential role of Drosophila Piezo in volume-based control of meal size, with neurons expressing Piezo responding to food reservoir organ distension. Activating Piezo neurons decreases appetite, while knockout and silencing of Piezo lead to gut bloating and increased food consumption and body weight.
Article Neurosciences

Identification of Novel Cross-Talk between the Neuroendocrine and Autonomic Stress Axes Controlling Blood Pressure

Khalid Elsaafien et al.

Summary: The PVNAgtr1a neurons play a key role in coordinating neuroendocrine axes and sympathetic nervous system responses to stress. These neurons synthesize CRH and activate neighboring neurons expressing CRHR1, ultimately regulating blood pressure in male mice through the hypothalamic-pituitary-adrenal axis and sympathetically mediated vasoconstriction.

JOURNAL OF NEUROSCIENCE (2021)

Article Neurosciences

Periphery signals generated by Piezo-mediated stomach stretch and Neuromedin-mediated glucose load regulate the Drosophila brain nutrient sensor

Yangkyun Oh et al.

Summary: Two satiety signals inhibiting DH44 nutrient sensor activity have been identified: Piezo-mediated stomach/crop stretch and Neuromedin/Hugin neurosecretory neurons activated by an increase in internal glucose levels. These signals work together to regulate DH44 sensor activity in fed flies.

NEURON (2021)

Article Cell Biology

An Atlas of Vagal Sensory Neurons and Their Molecular Specialization

Jussi Kupari et al.

CELL REPORTS (2019)

Review Neurosciences

A Student's Guide to Neural Circuit Tracing

Christine Saleeba et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

Genetic Identification of Vagal Sensory Neurons That Control Feeding

Ling Bai et al.

Article Biochemistry & Molecular Biology

A Neural Circuit for Gut-Induced Reward

Wenfei Han et al.

Article Multidisciplinary Sciences

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

Wei-Zheng Zeng et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Piezo2 senses airway stretch and mediates lung inflation-induced apnoea

Keiko Nonomura et al.

NATURE (2017)

Article Physiology

Sympathetic overactivity occurs before hypertension in the two-kidney, one-clip model

Elizabeth B. Oliveira-Sales et al.

EXPERIMENTAL PHYSIOLOGY (2016)

Article Neurosciences

Piezo2 is the principal mechanotransduction channel for proprioception

Seung-Hyun Woo et al.

NATURE NEUROSCIENCE (2015)

Article Multidisciplinary Sciences

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

Sanjeev S. Ranade et al.

NATURE (2014)

Review Physiology

Central pathways of pulmonary and lower airway vagal afferents

Leszek Kubin et al.

JOURNAL OF APPLIED PHYSIOLOGY (2006)

Review Physiology

Baroreceptors, baroreceptor unloading, and the long-term control of blood pressure

TN Thrasher

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)

Article Peripheral Vascular Disease

Relationship between central sympathetic activity and stages of human hypertension

PA Smith et al.

AMERICAN JOURNAL OF HYPERTENSION (2004)

Article Cardiac & Cardiovascular Systems

Sympathetic neural mechanisms in white-coat hypertension

PA Smith et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)

Article Neurosciences

Functional and chemical anatomy of the afferent vagal system

HR Berthoud et al.

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2000)