4.7 Article

Investigation of the Anti-Inflammatory Activity of Fusaproliferin Analogues Guided by Transcriptome Analysis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Food Science & Technology

Recent development in zebrafish model for bioactivity and safety evaluation of natural products

Fang-Jun Lin et al.

Summary: Zebrafish, a popular freshwater fish in aquariums and laboratories, has emerged as a valuable tool for rapidly screening safe and effective substances from natural products. With the ability to assess bioactivity and safety of natural products, zebrafish models show promising potential in discovering novel natural products with potential health benefits.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

Article Pharmacology & Pharmacy

N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-?B and MAPK Pathways

Li-Jun Huang et al.

Summary: This study reports the therapeutic efficacy of the small molecule N-acetyldopamine dimer (NADD) derived from Isaria cicadae in treating UC. NADD effectively relieves UC symptoms by inhibiting the expression of genes in the inflammation-related NF-kappa B and MAPK signaling pathways.

FRONTIERS IN PHARMACOLOGY (2022)

Article Pharmacology & Pharmacy

Pentamidine Alleviates Inflammation and Lipopolysaccharide-Induced Sepsis by Inhibiting TLR4 Activation via Targeting MD2

Siru Wu et al.

Summary: TLR4 plays a crucial role in immune response and protection against infection, but its overactivation can lead to sepsis. Pentamidine, identified as a TLR4 antagonist, inhibits the TLR4 signaling pathway and shows potential in alleviating inflammation and sepsis symptoms.

FRONTIERS IN PHARMACOLOGY (2022)

Article Plant Sciences

Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity

Feng Ju et al.

Summary: Aureonitol and its analogues isolated from Chaetomium elatum exhibit anti-neuroinflammatory activity by attenuating the production of inflammatory mediators. Compound 8 shows significant anti-inflammatory effects in microglial cells by reducing the levels of inducible nitric oxide synthase and cyclooxygenase-2.

JOURNAL OF NATURAL PRODUCTS (2021)

Review Multidisciplinary Sciences

The spectrum of inflammatory responses

Ruslan Medzhitov

Summary: Inflammation plays a crucial role in maintaining homeostasis and structural integrity of tissues and organs in animals. Recent research has revealed a wide range of biological processes involving inflammatory control, urging for a new framework beyond its traditional roles in defense against infection and injury. New perspectives and research directions are discussed to address the current gaps in understanding inflammation biology.

SCIENCE (2021)

Review Oncology

High-Throughput Strategies for the Discovery of Anticancer Drugs by Targeting Transcriptional Reprogramming

Lijun Huang et al.

Summary: This article summarizes the technological principles and applications of L1000 and HTS2, two high-throughput drug discovery approaches based on gene-expression signatures, and discusses their advantages and limitations in anticancer drug discovery.

FRONTIERS IN ONCOLOGY (2021)

Article Biotechnology & Applied Microbiology

Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi

Lan Jiang et al.

Summary: The study identified a unique BFTS sub-clade critical to the formation of a 5-15 trans-fused bicyclic sesterterpene and revealed that phytopathogenic fungi can serve as important sources of active terpenoids through systematic analysis of BFTS biosynthetic gene clusters.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2021)

Article Plant Sciences

Two new sesquiterpenes produced by the endophytic fungus Aspergillus fumigatus from Ligusticum wallichii

Sha Li et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2020)

Article Biochemistry & Molecular Biology

Bioactive triterpenoids from Lantana camara showing anti-inflammatory activities in vitro and in vivo

Peng Wu et al.

BIOORGANIC CHEMISTRY (2020)

Review Immunology

Increasing the Chemical Variety of Small-Molecule-Based TLR4 Modulators: An Overview

Alessio Romerio et al.

FRONTIERS IN IMMUNOLOGY (2020)

Article Chemistry, Medicinal

Anti-Inflammatory Cembranoids from a Formosa Soft Coral Sarcophyton cherbonnieri

Chia-Chi Peng et al.

MARINE DRUGS (2020)

Article Chemistry, Applied

Isochromanes from Aspergillus fumigatus, an endophytic fungus from Cordyceps sinensis

Xiao-Hua Li et al.

NATURAL PRODUCT RESEARCH (2019)

Review Microbiology

A Review of the Microbial Production of Bioactive Natural Products and Biologics

Janette Pham et al.

FRONTIERS IN MICROBIOLOGY (2019)

Review Biochemistry & Molecular Biology

The Pathogenesis of Sepsis and Potential Therapeutic Targets

Min Huang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Biochemistry & Molecular Biology

Role of Human Macrophage Polarization in Inflammation during Infectious Diseases

Chiraz Atri et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Pharmacology & Pharmacy

Raging the War Against Inflammation With Natural Products

Ali Attiq et al.

FRONTIERS IN PHARMACOLOGY (2018)

Article Biochemical Research Methods

iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

Steven Xijin Ge et al.

BMC BIOINFORMATICS (2018)

Article Chemistry, Medicinal

Anti-Inflammatory Cembranoids from the Soft Coral Lobophytum crassum

Kuei-Hung Lai et al.

MARINE DRUGS (2017)

Review Pharmacology & Pharmacy

Drugs for Autoimmune Inflammatory Diseases: From Small Molecule Compounds to Anti-TNF Biologics

Ping Li et al.

FRONTIERS IN PHARMACOLOGY (2017)

Article Plant Sciences

Bioactive Isoprenoid-Derived Natural Products from a Dongsha Atoll Soft Coral Sinularia erecta

Chiung-Yao Huang et al.

JOURNAL OF NATURAL PRODUCTS (2016)

Review Biochemistry & Molecular Biology

Stress, Inflammation, and Defense of Homeostasis

Raj Chovatiya et al.

MOLECULAR CELL (2014)

Review Biochemistry & Molecular Biology

Sesquiterpenoids Lactones: Benefits to Plants and People

Martin Chadwick et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Review Cell Biology

NF-κB, Inflammation, and Metabolic Disease

Rebecca G. Baker et al.

CELL METABOLISM (2011)

Review Biochemistry & Molecular Biology

Eritoran tetrasodium (E5564) treatment for sepsis: review of preclinical and clinical studies

Amisha Barochia et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2011)

Article Multidisciplinary Sciences

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

A. Phillip West et al.

NATURE (2011)

Article Critical Care Medicine

A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis

Todd W. Rice et al.

CRITICAL CARE MEDICINE (2010)

Review Biochemistry & Molecular Biology

Oxidative stress, inflammation, and cancer How are they linked?

Simone Reuter et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Biochemistry & Molecular Biology

Phosphorylation of SNAP-23 by IκB kinase 2 regulates mast cell degranulation

Kotaro Suzuki et al.

Article Hematology

Vav proteins control MyD88-dependent oxidative burst

Ana V. Miletic et al.

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Phytotoxic sesterterpene, 11-epiterpestacin, from Bipolaris sorokiniana NSDR-011

Y Nihashi et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)