4.7 Article

Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

MFG-E8 alleviates oxygen-glucose deprivation-induced neuronal cell apoptosis by STAT3 regulating the selective polarization of microglia

Ying-Ying Fang et al.

Summary: The study revealed that MFG-E8 reduced neuronal cell apoptosis by promoting M2 polarization of microglia, potentially providing a novel mechanism for ischemic stroke.

INTERNATIONAL JOURNAL OF NEUROSCIENCE (2021)

Article Multidisciplinary Sciences

MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program

Yi Wang et al.

Summary: Despite extensive studies, the mechanisms underlying PF remain poorly understood. This study found altered MBD2 expression in macrophages in lungs from different types of PF patients and mice with PF, and Mbd2 deficiency protected against BLM-induced PF. Mbd2 selectively influenced TGF-β1 production and M2 macrophage program through Ship promoter binding in macrophages.

SCIENCE ADVANCES (2021)

Article Nutrition & Dietetics

Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect

Xi Zhou et al.

Summary: The study revealed that DHM can delay the progression of liver fibrosis and inhibit HSCs activation by inducing autophagy and enhancing NK cell-mediated killing through the AhR-NF-kappa B/STAT3-IFN-gamma signaling pathway.

NUTRITION & METABOLISM (2021)

Article Medicine, Research & Experimental

Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition

Qi Wang et al.

Summary: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by abnormal transition and proliferation of fibroblasts, which lead to progressive damage to lung tissue. Effective therapeutic strategies to block this cellular transition are currently lacking.

THERANOSTICS (2021)

Article Medicine, Research & Experimental

TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis

Clara Dees et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Review Cell Biology

Regulators of glucose uptake in thyroid cancer cell lines

Shabnam Heydarzadeh et al.

CELL COMMUNICATION AND SIGNALING (2020)

Article Biochemistry & Molecular Biology

S100A2 promotes glycolysis and proliferation via GLUT1 regulation in colorectal cancer

Chen Li et al.

FASEB JOURNAL (2020)

Review Cell Biology

Cancer Metabolism: Phenotype, Signaling and Therapeutic Targets

Jae Hyung Park et al.

Article Pharmacology & Pharmacy

Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis

Kang Miao et al.

THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2020)

Article Physiology

Oxidative Stress in Pulmonary Fibrosis

Eva Otoupalova et al.

COMPREHENSIVE PHYSIOLOGY (2020)

Review Biochemistry & Molecular Biology

Developmental pathways in the pathogenesis of lung fibrosis

Diptiman Chanda et al.

MOLECULAR ASPECTS OF MEDICINE (2019)

Article Biotechnology & Applied Microbiology

MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells

Yong Liu et al.

MOLECULAR THERAPY (2019)

Review Pharmacology & Pharmacy

Management of Idiopathic Pulmonary Fibrosis

Roy Pleasants et al.

ANNALS OF PHARMACOTHERAPY (2019)

Review Biochemistry & Molecular Biology

Glut 1 in Cancer Cells and the Inhibitory Action of Resveratrol as A Potential Therapeutic Strategy

Angara Zambrano et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Editorial Material Critical Care Medicine

The 2018 Diagnosis of Idiopathic Pulmonary Fibrosis Guidelines: Surgical Lung Biopsy for Radiological Pattern of Probable Usual Interstitial Pneumonia Is Not Mandatory

Ganesh Raghu et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2019)

Review Respiratory System

Comorbidities in idiopathic pulmonary fibrosis: an underestimated issue

Antonella Caminati et al.

EUROPEAN RESPIRATORY REVIEW (2019)

Review Cardiac & Cardiovascular Systems

Inflammation and immunity in IPF pathogenesis and treatment

P. Heukels et al.

RESPIRATORY MEDICINE (2019)

Article Biochemistry & Molecular Biology

Defining the Activated Fibroblast Population in Lung Fibrosis Using Single-Cell Sequencing

Rebecca Peyser et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Glucose transporters in cancer - from tumor cells to the tumor microenvironment

Pierre-Benoit Ancey et al.

FEBS JOURNAL (2018)

Review Medicine, General & Internal

Idiopathic Pulmonary Fibrosis

David J. Lederer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Multidisciplinary Sciences

Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling

Lakmini Kumari Senavirathna et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

GLUT1 protects prostate cancer cells from glucose deprivation-induced oxidative stress

Pedro Gonzalez-Menendez et al.

REDOX BIOLOGY (2018)

Review Pharmacology & Pharmacy

Recent Update on the Pharmacological Effects and Mechanisms of Dihydromyricetin

Jingyao Zhang et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Medicine, General & Internal

Idiopathic pulmonary fibrosis

Luca Richeldi et al.

LANCET (2017)

Article Biochemistry & Molecular Biology

Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport

Arvindhan Nagarajan et al.

MOLECULAR CELL (2017)

Article Multidisciplinary Sciences

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis

Debomita Chakraborty et al.

NATURE COMMUNICATIONS (2017)

Article Medicine, Research & Experimental

Dihydromyricetin prevents monocrotaline-induced pulmonary arterial hypertension in rats

Qinghai Li et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Review Respiratory System

Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

Lutz Wollin et al.

EUROPEAN RESPIRATORY JOURNAL (2015)

Article Pathology

Pathogenesis of Idiopathic Pulmonary Fibrosis

Paul J. Wolters et al.

Annual Review of Pathology-Mechanisms of Disease (2013)