Internal light source for deep photodynamic therapy

Photodynamic therapy (PDT) for deep-seated lesion is seriously hindered by the limited depth of visible light penetration. Most recently, researchers have designed a genetically-encoded NanoLuc-miniSOG with internal light source for self-excitation, which is highly beneficial for deep PDT.

Automated summary

The limited penetration depth of visible light has hindered photodynamic therapy (PDT) for deep-seated lesions. However, researchers have recently developed a genetically-encoded NanoLuc-miniSOG with an internal light source for self-excitation, which greatly benefits deep PDT.