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注意：仅列出部分参考文献，下载原文获取全部文献信息。Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
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DIABETOLOGIA (2013)
Restoration of the Unfolded Protein Response in Pancreatic β Cells Protects Mice Against Type 1 Diabetes
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Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance
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Islet β-Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model
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Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes
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Identification of a Novel Binding Protein of FAT10: Eukaryotic Translation Elongation Factor 1A1
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The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
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Cytokines regulate neuronal gene expression: Differential effects of Th1, Th2 and monocyte/macrophage cytokines
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Modulating stress responses by the UPRosome: A matter of life and death
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TRENDS IN BIOCHEMICAL SCIENCES (2011)
Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction
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Replication and further characterization of a Type 1 diabetes-associated locus at the telomeric end of the major histocompatibility complex
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Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells
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The Ubiquitin-Like Protein FAT10 Mediates NF-κB Activation
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Signaling by IL-1β + IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis
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CELL DEATH AND DIFFERENTIATION (2009)
Virus-Induced Autoimmune Diabetes in the LEW.1WR1 Rat Requires Iddm14 and a Genetic Locus Proximal to the Major Histocompatibility Complex
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PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ-Induced Pancreatic β-Cell Apoptosis
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Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells
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DIABETOLOGIA (2008)
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Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon
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Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex
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The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-κB activation
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MOLECULAR ENDOCRINOLOGY (2006)
Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA plus interferon-γ-induced apoptosis in primary pancreatic β-cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic β-cells
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DIABETES (2005)
Expression of the FAT 10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers
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ONCOGENE (2003)
Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells
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DIABETES (2003)
Genetics of type 1 diabetes mellitus
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GENES AND IMMUNITY (2002)
Design and application of a cytokine-receptor-based interaction trap
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Identification of novel cytokine-induced genes in pancreatic β-cells by high-density oligonucleotide arrays
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Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1β-exposed human and rat islet cells
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The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic β-cells
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IB1 reduces cytokine-induced apoptosis of insulin-secreting cells
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