期刊
JOURNAL OF BIOLOGICAL CHEMISTRY
卷 291, 期 24, 页码 12529-12537出版社
AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/jbc.R116.720995
关键词
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资金
- Canada Institute of Health Research [81361, 123306, 13337, 43998]
- Cystic Fibrosis Canada [3019]
- Chercheur-Boursier Award from the Fonds de Recherche Quebec Sante (FRQS)
Exopolysaccharides play an important structural and functional role in the development and maintenance of microbial biofilms. Although the majority of research to date has focused on the exopolysaccharide systems of biofilm-forming bacteria, recent studies have demonstrated that medically relevant fungi such as Candida albicans and Aspergillus fumigatus also form biofilms during infection. These fungal biofilms share many similarities with those of bacteria, including the presence of secreted exopolysaccharides as core components of the extracellular matrix. This review will highlight our current understanding of fungal biofilm exopolysaccharides, as well as the parallels that can be drawn with those of their bacterial counterparts.
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