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Paulina H. Wanrooij et al.
DNA REPAIR (2015)
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MOLECULAR CELL (2015)
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response
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Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage
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EXPERIMENTAL CELL RESEARCH (2014)
The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks
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Anja M. Duursma et al.
MOLECULAR CELL (2013)
DNA Damage Response: Three Levels of DNA Repair Regulation
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COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Two Distinct Modes of ATR Activation Orchestrated by Rad17 and Nbs1
Bunsyo Shiotani et al.
CELL REPORTS (2013)
Conditional Inactivation of the DNA Damage Response Gene Hus1 in Mouse Testis Reveals Separable Roles for Components of the RAD9-RAD1-HUS1 Complex in Meiotic Chromosome Maintenance
Amy M. Lyndaker et al.
PLOS GENETICS (2013)
BRCT domains: A little more than kin, and less than kind
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FEBS LETTERS (2012)
Structure and conformational change of a replication protein A heterotrimer bound to ssDNA
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GENES & DEVELOPMENT (2012)
AIR signalling: more than meeting at the fork
Edward A. Nam et al.
BIOCHEMICAL JOURNAL (2011)
Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1
Mathieu Rappas et al.
NUCLEIC ACIDS RESEARCH (2011)
A Genome-Wide RNAi Screen Identifies Core Components of the G2-M DNA Damage Checkpoint
Shu Kondo et al.
SCIENCE SIGNALING (2011)
Casein kinase 2-dependent phosphorylation of human Rad9 mediates the interaction between human Rad9-Hus1-Rad1 complex and TopBP1
Yukimasa Takeishi et al.
GENES TO CELLS (2010)
Rad17 Plays a Central Role in Establishment of the Interaction between TopBP1 and the Rad9-Hus1-Rad1 Complex at Stalled Replication Forks
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MOLECULAR BIOLOGY OF THE CELL (2010)
BACH1/FANCJ Acts with TopBP1 and Participates Early in DNA Replication Checkpoint Control
Zihua Gong et al.
MOLECULAR CELL (2010)
TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forks
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JOURNAL OF CELL BIOLOGY (2009)
The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATM
Hae Yong Yoo et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
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GENES & DEVELOPMENT (2008)
The Rad9-Hus1-Rad1 checkpoint interaction of TopBP1 with ATR
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
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GENES & DEVELOPMENT (2007)
Function of a conserved checkpoint recruitment domain in ATRIP proteins
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MOLECULAR AND CELLULAR BIOLOGY (2007)
Drosophila ATR in double-strand break repair
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GENETICS (2007)
Direct requirement for Xmus 101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling
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JOURNAL OF CELL BIOLOGY (2006)
Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures
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GENES & DEVELOPMENT (2006)
TopBP1 activates the ATR-ATRIP complex
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CELL (2006)
Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint
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MOLECULAR AND CELLULAR BIOLOGY (2006)
ATRIP associates with replication protein A-coated ssDNA through multiple interactions
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans
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EMBO JOURNAL (2005)
ATRIP oligomerization is required for ATR-dependent checkpoint signaling
HL Ball et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation
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MOLECULAR BIOLOGY OF THE CELL (2005)
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
TS Byun et al.
GENES & DEVELOPMENT (2005)
ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining
HY Wang et al.
CANCER RESEARCH (2004)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
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SCIENCE (2003)
Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication
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EMBO JOURNAL (2003)
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication
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JOURNAL OF CELL BIOLOGY (2002)
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
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GENES & DEVELOPMENT (2002)
ATR and ATRIP: Partners in checkpoint signaling
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SCIENCE (2001)
Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
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GENES & DEVELOPMENT (2000)
Initiation of eukaryotic DNA replication:: Origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase α
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MOLECULAR CELL (2000)
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