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Mariko Yokogawa et al.
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Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers
Chaitali Parikh et al.
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Yoshihiro Kobashigawa et al.
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Wen-I Wu et al.
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Jonas Borch et al.
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Christine M. Coticchia et al.
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Sung Ji Yun et al.
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Veronique Calleja et al.
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T. K. Ritchie et al.
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Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises
Timothy A. Yap et al.
CURRENT OPINION IN PHARMACOLOGY (2008)
Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting
Jamil S. Saad et al.
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Biao Dong et al.
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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
John D. Carpten et al.
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Brendan D. Manning et al.
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Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo
Veronique Calleja et al.
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R. L. Dillon et al.
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Briony E. Cristiano et al.
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Lisa Heron-Milhavet et al.
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Jamil S. Saad et al.
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Hiroaki Ishida et al.
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HY Irie et al.
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Perturbations of the AKT signaling pathway in human cancer
DA Altomare et al.
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The CCPN data model for NMR spectroscopy: Development of a software pipeline
WF Vranken et al.
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S Cooray
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Genome-wide analysis of membrane targeting by S-cerevisiae pleckstrin homology domains
JW Yu et al.
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Structure, regulation and function of PKB/AKT - a major therapeutic target
M Hanada et al.
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D Auguin et al.
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TB Deb et al.
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AP Yamniuk et al.
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TH Bayburt et al.
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Novel aspects of calmodulin target recognition and activation
SW Vetter et al.
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Self-assembly of discoidal phospholipid bilayer nanoparticles with membrane scaffold proteins
TH Bayburt et al.
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CC Thomas et al.
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Initiating oncogenic event determines gene-expression patterns of human breast cancer models
KV Desai et al.
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KP Hoeflich et al.
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Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
G Pérez-Tenorio et al.
BRITISH JOURNAL OF CANCER (2002)
Calmodulin: a prototypical calcium sensor
D Chin et al.
TRENDS IN CELL BIOLOGY (2000)