相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Adaptation to hypoxia in Drosophila melanogaster requires autophagy
Ayelen Valko et al.
AUTOPHAGY (2022)
NHR-49/PPAR-α and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase
Khursheed A. Wani et al.
ELIFE (2021)
Cell nonautonomous roles of NHR-49 in promoting longevity and innate immunity
Nikki Naim et al.
AGING CELL (2021)
eVITTA: a web-based visualization and inference toolbox for transcriptome analysis
Xuanjin Cheng et al.
NUCLEIC ACIDS RESEARCH (2021)
Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model
Rongcan Luo et al.
AUTOPHAGY (2020)
HIPK2 overexpression relieves hypoxia/reoxygenation-induced apoptosis and oxidative damage of cardiomyocytes through enhancement of the Nrf2/ARE signaling pathway
Xiaoyan Dang et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2020)
Cellular adaptation to hypoxia through hypoxia inducible factors and beyond
Pearl Lee et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
NHR-49 Transcription Factor Regulates Immunometabolic Response and Survival of Caenorhabditis elegans during Enterococcus faecalis Infection
Madhumanti Dasgupta et al.
INFECTION AND IMMUNITY (2020)
HIF Inhibitors: Status of Current Clinical Development
Jaleh Fallah et al.
CURRENT ONCOLOGY REPORTS (2019)
The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy
Najah Albadari et al.
EXPERT OPINION ON DRUG DISCOVERY (2019)
Hypoxia exacerbates nonalcoholic fatty liver disease via the HIF-2α/PPARα pathway
Jiandi Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2019)
NHR-49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting
Grace Y. S. Goh et al.
AGING CELL (2018)
Advances in Hypoxia-Inducible Factor Biology
Hani Choudhry et al.
CELL METABOLISM (2018)
Fatty acid activation in carcinogenesis and cancer development: Essential roles of long-chain acyl-CoA synthetases
Yue Tang et al.
ONCOLOGY LETTERS (2018)
The receptor tyrosine kinase HIR-1 coordinates HIF-independent responses to hypoxia and extracellular matrix injury
Roman Vozdek et al.
SCIENCE SIGNALING (2018)
Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake
Srirupa Roy et al.
MOLECULAR CELL (2017)
Salmon provides fast and bias-aware quantification of transcript expression
Rob Patro et al.
NATURE METHODS (2017)
The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1restricted autophagy in Caenorhabditis elegans
Ritika Das et al.
PLOS GENETICS (2017)
Targeting renal cell carcinoma with a HIF-2 antagonist
Wenfang Chen et al.
NATURE (2016)
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
Hyejin Cho et al.
NATURE (2016)
Hypoxic control of metastasis
Erinn B. Rankin et al.
SCIENCE (2016)
Homeodomain-Interacting Protein Kinase (HPK-1) regulates stress responses and ageing in C. elegans
Slavica Berber et al.
SCIENTIFIC REPORTS (2016)
Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally Distinct
Kayoung Lee et al.
PLOS ONE (2016)
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
Luana Schito et al.
TRENDS IN CANCER (2016)
Tissue-specific autophagy responses to aging and stress in C-elegans
Hannah C. Chapin et al.
AGING-US (2015)
Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal
Kristopher Burkewitz et al.
CELL (2015)
SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans
T. Keith Blackwell et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span
Scott F. Leiser et al.
SCIENCE (2015)
Interplay between unfolded protein response and autophagy promotes tumor drug resistance (Review)
Ming-Ming Yan et al.
ONCOLOGY LETTERS (2015)
A HIF-Independent Mediator of Transcriptional Responses to Oxygen Deprivation in Caenorhabditis elegans
Divya Padmanabha et al.
GENETICS (2015)
The conserved Mediator subunit MDT-15 is required for oxidative stress responses in Caenorhabditis elegans
Grace Y. S. Goh et al.
AGING CELL (2014)
A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans
Manish Chamoli et al.
AGING CELL (2014)
Trimmomatic: a flexible trimmer for Illumina sequence data
Anthony M. Bolger et al.
BIOINFORMATICS (2014)
The C. elegans LC3 Acts Downstream of GABARAP to Degrade Autophagosomes by Interacting with the HOPS Subunit VPS39
Marion Manil-Segalen et al.
DEVELOPMENTAL CELL (2014)
Nutrient-sensing nuclear receptors coordinate autophagy
Jae Man Lee et al.
NATURE (2014)
Peroxisome proliferator-activated receptor a activation attenuates the inflammatory response to protect the liver from acute failure by promoting the autophagy pathway
M. Jiao et al.
CELL DEATH & DISEASE (2014)
Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans
Ramesh Ratnappan et al.
PLOS GENETICS (2014)
Tissue-specific changes in fatty acid oxidation in hypoxic heart and skeletal muscle
Andrea J. Morash et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2013)
Homeodomain Interacting Protein Kinase (HPK-1) is Required in the Soma for Robust Germline Proliferation in C. elegans
Slavica Berber et al.
DEVELOPMENTAL DYNAMICS (2013)
Extensive Rewiring and Complex Evolutionary Dynamics in a C. elegans Multiparameter Transcription Factor Network
John S. Reece-Hoyes et al.
MOLECULAR CELL (2013)
HIF- and Non-HIF-Regulated Hypoxic Responses Require the Estrogen-Related Receptor in Drosophila melanogaster
Yan Li et al.
PLOS GENETICS (2013)
Coordinate Regulation of Lipid Metabolism by Novel Nuclear Receptor Partnerships
Pranali P. Pathare et al.
PLOS GENETICS (2012)
Creating Defined Gaseous Environments to Study the Effects of Hypoxia on C-elegans
Emily M. Fawcett et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2012)
Hydrogen Sulfide and Cell Signaling
Ling Li et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 51, 2011 (2011)
The tailless ortholog nhr-67 functions in the development of the C. elegans ventral uterus
Eliana Verghese et al.
DEVELOPMENTAL BIOLOGY (2011)
Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL
Mingqing Li et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Regulation of Fat Storage and Reproduction by Kruppel-Like Transcription Factor KLF3 and Fat-Associated Genes in Caenorhabditis elegans
Jun Zhang et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans
Dana L. Miller et al.
PLOS ONE (2011)
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
Mark D. Robinson et al.
BIOINFORMATICS (2010)
Hydrogen Sulfide Increases Hypoxia-inducible Factor-1 Activity Independently of von Hippel-Lindau Tumor Suppressor-1 in C-elegans
Mark W. Budde et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Hypoxia signaling and resistance in C. elegans
Jo Anne Powell-Coffman
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Transcriptional regulation of hypoxia-inducible factor 1α by HIPK2 suggests a novel mechanism to restrain tumor growth
Lavinia Nardinocchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response
Marco A. Calzado et al.
NATURE CELL BIOLOGY (2009)
Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62
J-P Pursiheimo et al.
ONCOGENE (2009)
Autophagy protects against hypoxic injury in C-elegans
Victor Samokhvalov et al.
AUTOPHAGY (2008)
HIPKs: Jack of all trades in basic nuclear activities
Cinzia Rinaldo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
A comparative metabolomic study of NHR-49 in Caenorhabditis elegans and PPAR-α in the mouse
Helen J. Atherton et al.
FEBS LETTERS (2008)
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
Huafeng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
Julian Aragones et al.
NATURE GENETICS (2008)
The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
William G. Kaelin
NATURE REVIEWS CANCER (2008)
Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans
Dana L. Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
HIPK2: a multitalented partner for transcription factors in DNA damage response and development
Cinzia Rinaldo et al.
BIOCHEMISTRY AND CELL BIOLOGY (2007)
Hypoxia-inducible factors, stem cells, and cancer
Brian Keith et al.
CELL (2007)
The tailless ortholog nhr-67 regulates patterning of gene expression and morphogenesis in the C-elegans vulva
Jolene S. Fernandes et al.
PLOS GENETICS (2007)
Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation
Chanhee Kang et al.
GENES & DEVELOPMENT (2007)
Hypoxia converts human macrophages into triglyceride-loaded foam cells
Pontus Bostrom et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
MR Van Gilst et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Roles of the HIF-1 hypoxia-inducible factor during hypoxia response in Caenorhabditis elegans
C Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C-elegans
MR Van Gilst et al.
PLOS BIOLOGY (2005)
Expression and function of conserved nuclear receptor genes in Caenorhabditis elegans
CR Gissendanner et al.
DEVELOPMENTAL BIOLOGY (2004)
Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegans
TG Nystul et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans
T Bishop et al.
PLOS BIOLOGY (2004)
Gene expression profiling of cells, tissues, and developmental stages of the nematode C-elegans
SJ McKay et al.
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (2003)
The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia
HQ Jiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor α expression during hypoxia
S Narravula et al.
JOURNAL OF IMMUNOLOGY (2001)
Alterations in enzymes involved in fat metabolism after acute and chronic altitude exposure
SL Kennedy et al.
JOURNAL OF APPLIED PHYSIOLOGY (2001)