期刊
BIOMED RESEARCH INTERNATIONAL
卷 2022, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2022/7854303
关键词
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资金
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2015/09259-2]
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) [001]
- CAPES [001]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [303399/2018-0, 310572/2021-5]
This study aimed to evaluate the influence of previous levels of physical activity on hemodynamic, vascular, ventilatory, and functional outcomes after COVID-19 hospitalization. The results showed that individuals with lower levels of physical activity had impaired pulmonary function and walking performance compared to those with higher levels of physical activity.
Purpose. To evaluate the influence of previous levels of physical activity on hemodynamic, vascular, ventilatory, and functional outcomes after coronavirus disease 2019 (COVID-19) hospitalization. Methods. Sixty-three individuals with COVID-19 had their clinical status and previous levels (12 month) of physical activity (Baecke Questionnaire of Habitual Physical Activity) assessed at hospital admission. Individuals were then allocated to lower levels of physical activity (ACT(LOWER); N=22), intermediate levels of physical activity (ACT(INTERMEDIATE); N=22), or higher levels of physical activity (ACT(HIGHER); N=19) groups, according to tertiles of physical activity. Resting hemodynamic (heart rate and brachial/central blood pressures) and vascular (carotid-femoral pulse wave velocity, augmentation index, and brachial artery flow-mediated dilation) variables, pulmonary function (spirometry), respiratory muscle strength (maximal respiratory pressures), and functional capacity (handgrip strength, five-time sit-to-stand, timed-up and go, and six-minute walking tests) were measured at 30 to 45 days after hospital discharge. Results. ACT(LOWER) showed lower levels (P < 0.05) of forced vital capacity, forced expiratory volume in the first second, maximal voluntary ventilation, and maximal expiratory pressure than ACT(HIGHER). ACT(LOWER) also had lower (P=0.023) walking distance (~21%,) and lower percentage of predicted walking distance (~20%) at six-minute walking test during follow-up than ACT(INTERMEDIATE). However, hemodynamic and vascular variables, handgrip strength, five-time sit-to-stand, and timed-up and go were not different among groups. Conclusion. ACT(LOWER) showed impaired ventilatory parameters and walking performance when compared with ACT(HIGHER) and ACT(INTERMEDIATE), respectively. These results suggest that previous levels of physical activity may impact ventilatory and exercise capacity outcomes 30 to 45 days after COVID-19 hospitalization discharge.
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