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Dysfunction of the PI3 kinase/Rap1/integrin αIIbβ3 pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia
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The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways
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Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis
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Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes
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Distinct Roles for Rap1b Protein in Platelet Secretion and Integrin αIIbβ3 Outside-in Signaling
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Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
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Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets
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Non-redundant Roles of Phosphoinositide 3-Kinase Isoforms α and β in Glycoprotein VI-induced Platelet Signaling and Thrombus Formation
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Protein Kinase C-mediated Phosphorylation and Activation of PDE3A Regulate cAMP Levels in Human Platelets
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The Ability of GAP1IP4BP To Function as a Rap1 GTPase-Activating Protein (GAP) Requires Its Ras GAP-Related Domain and an Arginine Finger Rather than an Asparagine Thumb
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Ligand density dramatically affects integmn αIIbβ3-mediated platelet signaling and spreading
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Versatile roles of R-Ras GAP in neurite formation of PC12 cells and embryonic vascular development
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GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins
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Relationships between Rap1b, affinity modulation of integrin αIIbβ3, and the actin cytoskeleton
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A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets
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Regulation of RAS in human platelets - Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation
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