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Mechanism of Self-Healing Hydrogels and Application in Tissue Engineering

期刊

POLYMERS
卷 14, 期 11, 页码 -

出版社

MDPI
DOI: 10.3390/polym14112184

关键词

hydrogels; self-healing; mechanism; tissue engineering application

资金

  1. Sichuan Science and Technology Program [2020YFH0008]
  2. National Key R&D Program of China [2020YFF0426289]

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Self-healing hydrogels have the ability to automatically repair damage and avoid premature failure caused by mechanical damage. Researchers can design hydrogels to meet the needs of different tissues.
Self-healing hydrogels and traditional hydrogels both have three-dimensional polymeric networks that are capable of absorbing and retaining a large amount of water. Self-healing hydrogels can heal and restore damage automatically, and they can avoid premature failure of hydrogels caused by mechanical damage after implantation. The formation mechanism of self-healing hydrogels and the factors that hydrogels can load are various. Researchers can design hydrogels to meet the needs of different tissues through the diversity of hydrogels Therefore, it is necessary to summarize different self-healing mechanisms and different factors to achieve different functions. Here, we briefly reviewed the hydrogels designed by researchers in recent years according to the self-healing mechanism of water coagulation. Then, the factors for different functions of self-healing hydrogels in different tissues were statistically analyzed. We hope our work can provide effective support for researchers in the design process of self-healing hydrogel.

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