4.7 Review

Fabrication of Polymer Microfluidics: An Overview

期刊

POLYMERS
卷 14, 期 10, 页码 -

出版社

MDPI
DOI: 10.3390/polym14102028

关键词

polymer microfluidics; micro-embossing; micro-injection molding; PDMS casting; CNC micromachining; laser micromachining; 3D printing

资金

  1. Ministry of Science and Technology in Taiwan [MOST 110-2221-E-006-019-MY3]

向作者/读者索取更多资源

Microfluidic platform technology provides a new strategy for the detection and analysis of analytes and biological entities by reducing dimensions. It enables the manipulation of particles through various forces and has become a popular choice for repeated short-time monitoring and affordable one-time usage with its diverse material properties and processing techniques.
Microfluidic platform technology has presented a new strategy to detect and analyze analytes and biological entities thanks to its reduced dimensions, which results in lower reagent consumption, fast reaction, multiplex, simplified procedure, and high portability. In addition, various forces, such as hydrodynamic force, electrokinetic force, and acoustic force, become available to manipulate particles to be focused and aligned, sorted, trapped, patterned, etc. To fabricate microfluidic chips, silicon was the first to be used as a substrate material because its processing is highly correlated to semiconductor fabrication techniques. Nevertheless, other materials, such as glass, polymers, ceramics, and metals, were also adopted during the emergence of microfluidics. Among numerous applications of microfluidics, where repeated short-time monitoring and one-time usage at an affordable price is required, polymer microfluidics has stood out to fulfill demand by making good use of its variety in material properties and processing techniques. In this paper, the primary fabrication techniques for polymer microfluidics were reviewed and classified into two categories, e.g., mold-based and non-mold-based approaches. For the mold-based approaches, micro-embossing, micro-injection molding, and casting were discussed. As for the non-mold-based approaches, CNC micromachining, laser micromachining, and 3D printing were discussed. This review provides researchers and the general audience with an overview of the fabrication techniques of polymer microfluidic devices, which could serve as a reference when one embarks on studies in this field and deals with polymer microfluidics.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据