4.6 Review

Foundations of circadian medicine

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Recent Advances in the Development of Casein Kinase 1 Inhibitors

Sha-Sha Li et al.

Summary: This review discusses the current state of development of CK1 inhibitors, including synthetic small molecules and natural compounds, providing an overview of existing inhibitors, their activities, and structure-activity relationships. Through physicochemical characterization and biological investigations, the structure-activity relationship of CK1 inhibitors can be understood, leading to the better design and discovery of potent and selective CK1 inhibitors for severe disorders such as AD, ALS, and cancer.

CURRENT MEDICINAL CHEMISTRY (2021)

Review Physiology

Mammalian circadian systems: Organization and modern life challenges

Anna-Marie Finger et al.

Summary: The endogenous circadian clock system in humans and other mammals is crucial for health, but modern lifestyles with artificial lighting, shift work, and travel across time zones can disrupt this system and lead to associated diseases. This review highlights the importance of a functional clock machinery and alignment between body clocks, as well as the impact of circadian disruption on health.

ACTA PHYSIOLOGICA (2021)

Review Endocrinology & Metabolism

Understanding the Concept of Chronotherapeutics in the Management of Diabetes Mellitus

Shilpi Kashyap et al.

Summary: Circadian rhythms are controlled by the circadian clock in the hypothalamus, specifically the suprachiasmatic nucleus, and chronotherapeutics play a crucial role in the treatment of disorders, particularly diabetes. Timing of daily activities and medication has a significant impact on glucose levels in the blood, affecting the risks of obesity, diabetes, cardiovascular diseases, and mortality.

CURRENT DIABETES REVIEWS (2021)

Article Endocrinology & Metabolism

New Horizons: Circadian Control of Metabolism Offers Novel Insight Into the Cause and Treatment of Metabolic Diseases

Shaunak Deota et al.

Summary: Metabolic homeostasis is regulated by endocrine factors, signaling cascades, and metabolic pathways, which are also modulated by circadian rhythm. Disruption of circadian rhythm can increase the risk for metabolic diseases. Understanding factors affecting circadian rhythm allows for implementing new interventions to prevent and manage metabolic disorders.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2021)

Review Neurosciences

Circadian and Sleep Dysfunctions in Neurodegenerative Disorders-An Update

Karim Fifel et al.

Summary: Disruptions of sleep and circadian rhythms are common symptoms in patients with neurodegenerative diseases, which may influence disease progression and exacerbate symptoms. There is a more comprehensive understanding of sleep and circadian dysregulation in these diseases currently available.

FRONTIERS IN NEUROSCIENCE (2021)

Review Biotechnology & Applied Microbiology

Circadian rhythm as a therapeutic target

Wei Ruan et al.

Summary: The circadian clock plays a crucial role in integrating external environmental changes and internal physiology, providing temporal precision and robust adaptation to the environment. Disruption of circadian rhythms can lead to adverse health consequences, but there is still an underappreciation of how to take advantage of biological timing for health benefits. Promising progress in research and clinical applications should drive efforts towards a new era of circadian medicine.

NATURE REVIEWS DRUG DISCOVERY (2021)

Review Medicine, General & Internal

Circadian Mechanisms in Medicine

Ravi Allada et al.

Summary: Studying the diurnal variations in human physiology and behavior can enhance our understanding of various disease processes, while chronobiology offers testable hypotheses on treatment timing.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Review Immunology

Circadian clock genes as promising therapeutic targets for autoimmune diseases

Kun Xiang et al.

Summary: Circadian rhythm plays a crucial role in immune system function, with disruptions to clock genes increasing the risk of autoimmune diseases. Research on synthetic ligands of circadian clock genes may help reduce the susceptibility and severity of autoimmune diseases.

AUTOIMMUNITY REVIEWS (2021)

Article Endocrinology & Metabolism

SERUM MORNING CORTISOL AS A SCREENING TEST FOR ADRENAL INSUFFICIENCY

Juan Montes-Villarreal et al.

ENDOCRINE PRACTICE (2020)

Review Endocrinology & Metabolism

Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes

Ivy C. Mason et al.

DIABETOLOGIA (2020)

Review Biology

Sleep, circadian rhythms and health

Russell G. Foster

INTERFACE FOCUS (2020)

Review Biochemistry & Molecular Biology

Coupled network of the circadian clocks: a driving force of rhythmic physiology

Anna-Marie Finger et al.

FEBS LETTERS (2020)

Article Microbiology

Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes

Sandra Reitmeier et al.

CELL HOST & MICROBE (2020)

Article Endocrinology & Metabolism

Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer

Faraz Bishehsari et al.

NATURE REVIEWS ENDOCRINOLOGY (2020)

Article Economics

Sunset time and the economic effects of social jetlag: evidence from US time zone borders

Osea Giuntella et al.

JOURNAL OF HEALTH ECONOMICS (2019)

Review Cell Biology

Medicine in the Fourth Dimension

Christopher R. Cederroth et al.

CELL METABOLISM (2019)

Article Multidisciplinary Sciences

Light-entrained and brain-tuned circadian circuits regulate ILC3s and gut homeostasis

Cristina Godinho-Silva et al.

NATURE (2019)

Article Public, Environmental & Occupational Health

Rotating night shift work and risk of multiple sclerosis in the Nurses' Health Studies

Kyriaki Papantoniou et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2019)

Editorial Material Multidisciplinary Sciences

Dosing time matters

Marc D. Ruben et al.

SCIENCE (2019)

Editorial Material Endocrinology & Metabolism

The arrival of circadian medicine

Satchidananda Panda

NATURE REVIEWS ENDOCRINOLOGY (2019)

Review Endocrinology & Metabolism

Circadian clocks and insulin resistance

Dirk Jan Stenvers et al.

NATURE REVIEWS ENDOCRINOLOGY (2019)

Review Endocrinology & Metabolism

A Review of the Relationship between Night Eating Syndrome and Body Mass Index

Maija B. Bruzas et al.

CURRENT OBESITY REPORTS (2019)

Review Psychiatry

Sleep, circadian rhythms, and schizophrenia: where we are and where we need to go

Jan Cosgrave et al.

CURRENT OPINION IN PSYCHIATRY (2018)

Article Medicine, Research & Experimental

High-accuracy determination of internal circadian time from a single blood sample

Nicole Wittenbrink et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Biochemistry & Molecular Biology

Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock

Kenneth Allen Dyar et al.

PLOS BIOLOGY (2018)

Review Genetics & Heredity

Transcriptional architecture of the mammalian circadian clock

Joseph S. Takahashi

NATURE REVIEWS GENETICS (2017)

Review Clinical Neurology

Genetic Basis of Chronotype in Humans: Insights From Three Landmark GWAS

David A. Kalmbach et al.

Review Clinical Neurology

Genetic Basis of Chronotype in Humans: Insights From Three Landmark GWAS

David A. Kalmbach et al.

Article Biology

The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin

Emma Henriksson et al.

JOURNAL OF BIOLOGICAL RHYTHMS (2017)

Article Multidisciplinary Sciences

CYCLOPS reveals human transcriptional rhythms in health and disease

Ron C. Anafi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Pharmacology & Pharmacy

Chronotherapy: Intuitive, Sound, FoundedaEuro¦But Not Broadly Applied

Julia M. Selfridge et al.

Article Cell Biology

Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

Guangrui Yang et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

Global and hepatocyte-specific ablation of Bmal1 induces hyperlipidaemia and enhances atherosclerosis

Xiaoyue Pan et al.

NATURE COMMUNICATIONS (2016)

Review Rheumatology

Clocking in: chronobiology in rheumatoid arthritis

Frank Buttgereit et al.

NATURE REVIEWS RHEUMATOLOGY (2015)

Review Pharmacology & Pharmacy

Recent advances in circadian rhythms in cardiovascular system

Lihong Chen et al.

FRONTIERS IN PHARMACOLOGY (2015)

Article Multidisciplinary Sciences

A circadian gene expression atlas in mammals: Implications for biology and medicine

Ray Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Endocrinology & Metabolism

The Suprachiasmatic Nucleus Controls Circadian Energy Metabolism and Hepatic Insulin Sensitivity

Claudia P. Coomans et al.

DIABETES (2013)

Article Multidisciplinary Sciences

Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6Chi Inflammatory Monocytes

Khoa D. Nguyen et al.

SCIENCE (2013)

Article Biochemistry & Molecular Biology

Social Jetlag and Obesity

Till Roenneberg et al.

CURRENT BIOLOGY (2012)

Review Biochemistry & Molecular Biology

Obesity in mice with adipocyte-specific deletion of clock component Arntl

Georgios K. Paschos et al.

NATURE MEDICINE (2012)

Article Multidisciplinary Sciences

The human circadian metabolome

Robert Dallmann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Identification of Small Molecule Activators of Cryptochrome

Tsuyoshi Hirota et al.

SCIENCE (2012)

Article Immunology

Dysregulation of Inflammatory Responses by Chronic Circadian Disruption

Oscar Castanon-Cervantes et al.

JOURNAL OF IMMUNOLOGY (2010)

Review Endocrinology & Metabolism

Late-night salivary cortisol measurement in the diagnosis of Cushing's syndrome

Ty Carroll et al.

NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2008)

Review Clinical Neurology

Epidemiology of the human circadian clock

Till Roenneberg et al.

SLEEP MEDICINE REVIEWS (2007)

Letter Biochemistry & Molecular Biology

Chronic jet-lag increases mortality in aged mice

A. J. Davidson et al.

CURRENT BIOLOGY (2006)

Article Public, Environmental & Occupational Health

Shiftwork and metabolic risk factors of cardiovascular disease

M Ha et al.

JOURNAL OF OCCUPATIONAL HEALTH (2005)

Article Multidisciplinary Sciences

Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex

VY Gorbacheva et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Oncology

Night-shift work and risk of colorectal cancer in the Nurses' Health Study

ES Schernhammer et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)

Article Psychiatry

Sundowning and circadian rhythms in Alzheimer's disease

L Volicer et al.

AMERICAN JOURNAL OF PSYCHIATRY (2001)