☆ 4.6 Editorial Material

The silent loss of cell physiology hampers marine biosciences

PLOS BIOLOGY (2022)

Molecular biologists: let's reconnect with nature

Edith Heard

NATURE (2022)

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Article Multidisciplinary Sciences

Signatures of selection underpinning rapid coral adaptation to the world's warmest reefs

Edward G. Smith et al.

Summary: By studying the population genomics of the brain coral in the Persian/Arabian Gulf (PAG), researchers have found that the corals in the PAG represent a distinct subpopulation that was established during the Holocene marine transgression. The genomes of these corals contain selective sweeps associated with thermal adaptation. Although there is limited potential for genetic rescue of neighboring Indian Ocean reefs, there is hope that loci associated with thermal tolerance may exist in the standing genetic variation of corals outside of the PAG.

SCIENCE ADVANCES (2022)

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Article Biochemistry & Molecular Biology

Cell states beyond transcriptomics: Integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

Kaytlyn A. Gerbin et al.

Summary: A quantitative, imaging-based platform was developed to classify subcellular organization in individual cells, producing a dataset on cardiomyocytes that describes population distributions. The study found that while mRNA abundance of certain genes correlated with subcellular organization, these metrics were often heterogeneous and uncorrelated, indicating that gene expression alone is insufficient for classifying cell states.

CELL SYSTEMS (2021)

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Letter Ecology