Rehabilitation Interventions for Post-Acute COVID-19 Syndrome: A Systematic Review

Article Rehabilitation

Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of cognitive impairment in post-acute sequelae of SARS-CoV-2 infection (PASC) patients

Jeffrey S. Fine et al.

PM&R (2022)

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Article Rehabilitation

Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of breathing discomfort and respiratory sequelae in patients with post-acute sequelae of SARS-CoV-2 infection (PASC)

Jason H. Maley et al.

PM&R (2022)

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Article Rehabilitation

Comparative effectiveness study of low versus high-intensity aerobic training with resistance training in community-dwelling older men with post-COVID 19 sarcopenia: A randomized controlled trial

Gopal Nambi et al.

Summary: The study found that low-intensity aerobic training combined with resistance training was more effective in improving clinical and psychological indicators in older men with post-COVID-19 sarcopenia symptoms, including handgrip strength, kinesiophobia level, and quality of life.

CLINICAL REHABILITATION (2022)

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Article Respiratory System

A telerehabilitation programme in post-discharge COVID-19 patients (TERECO): a randomised controlled trial

Jian'an Li et al.

Summary: The study found that the telerehabilitation programme TERECO was superior to no rehabilitation in improving exercise capacity, lower limb muscle strength (LMS), and physical health-related quality of life (HRQOL) in COVID-19 survivors with remaining dyspnoea complaints.

THORAX (2022)

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Review Cardiac & Cardiovascular Systems

The effectiveness of pulmonary rehabilitation for Post-COVID symptoms: A rapid review of the literature

Lesley J. J. Soril et al.

Summary: Limited clinical effectiveness studies have been conducted on post-COVID PR, but existing research suggests that PR can improve exercise capacity, pulmonary function, and quality of life for individuals hospitalized with acute COVID-19 infection. It may also alleviate symptoms such as dyspnea, fatigue, anxiety, and depression. However, there is a lack of research on non-hospitalized patients or long-term outcomes beyond 3 months after initiating PR.

RESPIRATORY MEDICINE (2022)

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Article Public, Environmental & Occupational Health

How and why patients made Long Covid

Felicity Callard et al.

Summary: Patients collectively created "Long Covid" and similar terms during the early months of the pandemic, demonstrating a longer and more complex illness course than initially reported. They used social media to spread their experiences and influence formal clinical and policy channels, showing how patients can contribute to changing the understanding and treatment of COVID-19.

SOCIAL SCIENCE & MEDICINE (2021)

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Letter Infectious Diseases

Post-COVID-19 functional status six-months after hospitalization

Manuel Taboada et al.

JOURNAL OF INFECTION (2021)

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Article Critical Care Medicine

Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care

Ann M. Parker et al.

Summary: As of July 31, 2021, nearly 200 million people worldwide have been infected with SARS-CoV-2, leading to substantial burden of long-term health effects such as fatigue, dyspnoea, cognitive and mental health impairments. A coordinated, multidisciplinary approach is necessary to address these complex health impairments.

LANCET RESPIRATORY MEDICINE (2021)

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Review Biochemistry & Molecular Biology

Post-acute COVID-19 syndrome

Ani Nalbandian et al.

Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.

NATURE MEDICINE (2021)

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Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Review Environmental Sciences

Long Covid-19: Proposed Primary Care Clinical Guidelines for Diagnosis and Disease Management

Antoni Siso-Almirall et al.

Summary: Long COVID-19 refers to patients who continue to have signs and symptoms four weeks after the diagnosis of SARS-CoV-2 infection, with an estimated frequency of around 10%. The long-term manifestations are similar to other coronaviruses like SARS and MERS, mainly affecting the respiratory, musculoskeletal, and neuropsychiatric systems. Managing long COVID-19 requires a structured primary care approach, multidisciplinary rehabilitation services, and empowerment of affected patient groups based on limited evidence.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Article Geriatrics & Gerontology

Health-related quality of life, functional decline, and long-term mortality in older patients following hospitalisation due to COVID-19

M. M. Walle-Hansen et al.

Summary: More than half of the patients reported a negative change in HR-QoL 6 months following hospitalisation due to COVID-19, and one out of three experienced a persistently impaired mobility and ability to carry out activities of daily living. The results suggest awareness of long-term functional decline in older COVID-19 patients.

BMC GERIATRICS (2021)

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Letter Rehabilitation

Rehabilitation and COVID-19: update of the rapid living systematic review by Cochrane Rehabilitation Field as of April 30, 2021

Francesco Negrini et al.

EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE (2021)

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Review Orthopedics

Apparent Discordance Between the Epidemiology of COVID-19 and Recommended Outcomes and Treatments: A Scoping Review

Sandra C. Webber et al.

Summary: The review examined assessment and treatment recommendations for postacute COVID-19 in adults, recommending outcomes such as exercise tolerance, respiratory function, muscle strength, and activities of daily living. Recommended treatments include respiratory rehabilitation, exercise therapy, education, psychological support, and traditional Chinese medicine. There were discrepancies between what is known about postacute COVID-19 and what was recommended, emphasizing the importance of developing tools for self-management and ensuring access to rehabilitation specialists.

PHYSICAL THERAPY (2021)

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Article Multidisciplinary Sciences

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis

Sandra Lopez-Leon et al.

Summary: This study aimed to identify studies assessing the long-term effects of COVID-19, estimating that 80% of infected patients will develop one or more long-term symptoms, with the most common being fatigue, headache, attention disorder, hair loss, and dyspnea.

SCIENTIFIC REPORTS (2021)

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Article Rehabilitation

Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fatigue in postacute sequelae of SARS-CoV-2 infection (PASC) patients

Joseph E. Herrera et al.

PM&R (2021)

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Review Medicine, General & Internal

Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19 A Systematic Review

Tahmina Nasserie et al.

Summary: COVID-19 infection is associated with persistent symptoms such as shortness of breath, fatigue, and insomnia. Current studies on symptom persistence are highly heterogeneous, and future research needs longer follow-up, improved quality, and more standardized designs to accurately quantify risks.

JAMA NETWORK OPEN (2021)

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Article Sport Sciences