期刊
出版社
MDPI
DOI: 10.3390/ijerph19074133
关键词
COVID-19; long COVID; rehabilitation; cognition; exercise; physical activity; respiratory rehabilitation
资金
- Fonds de Recherche du Quebec-Sante (FRQ-S)
- Mirella and Lino Saputo Research Chair in Cardiovascular Health
- Prevention of Cognitive Deficits from University of Montreal at the Montreal Heart Institute
- Montreal Heart Institute Foundation
The COVID-Rehab study investigates the effectiveness of an eight-week cardiopulmonary rehabilitation program for long-term COVID-19 patients. The study examines multiple outcomes including cardiorespiratory fitness, quality of life, and cognition. The findings will provide important guidance for the rehabilitation of long-term COVID-19 patients.
(1) Background: Cardiopulmonary and brain functions are frequently impaired after COVID-19 infection. Exercise rehabilitation could have a major impact on the healing process of patients affected by long COVID-19. (2) Methods: The COVID-Rehab study will investigate the effectiveness of an eight-week cardiopulmonary rehabilitation program on cardiorespiratory fitness ((V)Over dotO(2)max) in long-COVID-19 individuals. Secondary objectives will include functional capacity, quality of life, perceived stress, sleep quality (questionnaires), respiratory capacity (spirometry test), coagulation, inflammatory and oxidative-stress profile (blood draw), cognition (neuropsychological tests), neurovascular coupling and pulsatility (fNIRS). The COVID-Rehab project was a randomised clinical trial with two intervention arms (1:1 ratio) that will be blindly evaluated. It will recruit a total of 40 individuals: (1) rehabilitation: centre-based exercise-training program (eight weeks, three times per week); (2) control: individuals will have to maintain their daily habits. (3) Conclusions: Currently, there are no specific rehabilitation guidelines for long-COVID-19 patients, but preliminary studies show encouraging results.
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