4.8 Article

Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Editorial Material Oncology

Whole-genome sequencing of East Asian lung cancers reveals new germline pathogenic variants

Semanti Mukherjee et al.

Summary: In this study, Wang et al. used whole-genome sequencing to comprehensively analyze common and rare variants associated with lung cancer risk in individuals with East Asian ancestry. Their findings suggest that rare promoter variants in the BRCA2 gene are associated with an increased risk of lung cancer.

CANCER CELL (2022)

Article Cell Biology

Type I interferon decreases macrophage energy metabolism during mycobacterial infection

Gregory S. Olson et al.

Summary: Metabolic reprogramming and transcriptional responses of murine macrophages to Mycobacterium tuberculosis are influenced by type I interferon signaling, which controls glycolytic shift and mitochondrial damage. This feedback loop may play a role in regulating macrophage responses to mycobacteria.

CELL REPORTS (2021)

Review Biochemistry & Molecular Biology

The JAK/STAT signaling pathway: from bench to clinic

Xiaoyi Hu et al.

Summary: The JAK/STAT signaling pathway is a crucial cellular signal transduction pathway, associated with various cancers and autoimmune diseases. Researchers discussed the composition, activation, and regulation of this pathway, as well as its role in diseases.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

Review Immunology

GM-CSF in inflammation

John A. Hamilton

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Review Multidisciplinary Sciences

Mitochondrial TCA cycle metabolites control physiology and disease

Inmaculada Martinez-Reyes et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Succination inactivates gasdermin D and blocks pyroptosis

Fiachra Humphries et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate

Wei Qin et al.

NATURE CHEMICAL BIOLOGY (2019)

Article Medicine, Research & Experimental

Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages

David P. De Souza et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Article Multidisciplinary Sciences

4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects

Shan-Ting Liao et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Malonylation of GAPDH is an inflammatory signal in macrophages

Silvia Galvan-Pena et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Epigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages

Amy T. Hsu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Multidisciplinary Sciences

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills et al.

NATURE (2018)

Article Multidisciplinary Sciences

Interferon stimulation creates chromatin marks and establishes transcriptional memory

Rui Kamada et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Multidisciplinary Sciences

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

W. K. Eddie Ip et al.

SCIENCE (2017)

Article Biochemistry & Molecular Biology

Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels

Thekla Cordes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Medicine, Research & Experimental

Granulocyte macrophage colony-stimulating factor induces CCL17 pro uction via IRF4 to mediate inflammation

Adrian Achuthan et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Biochemistry & Molecular Biology

Application of dynamic metabolomics to examine in vivo skeletal muscle glucose metabolism in the chronically high-fat fed mouse

Greg M. Kowalski et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling

Autumn G. York et al.

Article Multidisciplinary Sciences

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

Bryce W. Carey et al.

NATURE (2015)

Article Multidisciplinary Sciences

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

G. M. Tannahill et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

ACCELERATED PUBLICATION The mitochondrial citrate carrier: a new player in inflammation

Vittoria Infantino et al.

BIOCHEMICAL JOURNAL (2011)

Review Immunology

The IRF family transcription factors in immunity and oncogenesis

Tomohiko Tamura et al.

ANNUAL REVIEW OF IMMUNOLOGY (2008)