4.7 Article

Optimization of intraperitoneal aerosolized drug delivery using computational fluid dynamics (CFD) modeling

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract

Fen Huang et al.

Summary: The effective evaluation and prediction of aerosol transport deposition in human respiratory tracts are critical to aerosol drug delivery and inhalation product evaluation. Computational fluid dynamics (CFD) based in silico modeling has rapidly developed in the past two decades, particularly with the coupling of discrete phase model (DPM) and discrete element method (DEM) approaches. Future research recommendations include improving in silico prediction to achieve better in vitro -in vivo correlation (IVIVC).

ADVANCED DRUG DELIVERY REVIEWS (2021)

Article Oncology

Experimental evaluation of icodextrin delivery as pressurized aerosol (PIPAC): Antiadhesive and cytotoxic effects

Helen Salome Keck et al.

Summary: The study demonstrates the feasibility of using Icodextrin solution as a carrier for pressurized intraperitoneal aerosol chemotherapy with Cisplatin and Doxorubicin. Icodextrin remains stable after aerosolization, significantly affects the adhesion of gastric cancer cells, and does not impair the cytotoxic effects of the chemotherapeutic drugs.
Article Engineering, Biomedical

Electrostatic Intraperitoneal Aerosol Delivery of Nanoparticles: Proof of Concept and Preclinical Validation

Leen Van de Sande et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Review Pharmacology & Pharmacy

Peritoneal cancer treatment

Yutaka Yonemura et al.

EXPERT OPINION ON PHARMACOTHERAPY (2014)

Review Gastroenterology & Hepatology

Peritoneal carcinomatosis

Federico Coccolini et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2013)

Article Surgery

Therapeutic approach of human peritoneal carcinomatosis with Dbait in combination with capnoperitoneum: proof of concept

Wiebke Solass et al.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2012)

Article Surgery

Description of a novel approach for intraperitoneal drug delivery and the related device

Wiebke Solass et al.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2012)

Review Oncology

Intraperitoneal therapy for peritoneal tumors: biophysics and clinical evidence

Wim P. Ceelen et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2010)

Article Engineering, Chemical

Numerical Simulation of Particle Dispersion in the Wake of a Circular Cylinder

Jun Yao et al.

AEROSOL SCIENCE AND TECHNOLOGY (2009)

Review Physiology

Modeling airflow and particle transport/deposition in pulmonary airways

Clement Kleinstreuer et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2008)