4.7 Article

mRNA-miRNA bipartite networks reconstruction in different tissues of bladder cancer based on gene co-expression network analysis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Urology & Nephrology

LINC00649 Facilitates the Cellular Process of Bladder Cancer Cells via Signaling Axis miR-16-5p/JARID2

Yongsong Liu et al.

Summary: This study revealed that LINC00649 enhances cell proliferation, migration, and invasion of bladder cancer cells by acting as a sponge of miR-16-5p and upregulating JARID2, providing novel insight into understanding bladder cancer.

UROLOGIA INTERNATIONALIS (2022)

Article Neurosciences

Identification of dysregulated pathways underlying HTLV-1-associated myelopathy/tropical spastic paraparesis through co-expression network analysis

Mohadeseh Zarei Ghobadi et al.

Summary: The study found significant differences in gene expression networks between HAM/TSP patients and healthy individuals, with modules enriched in pathways related to the immune system, cell cycle, viral infection, and neuronal systems. Furthermore, novel immunological and neurological-related proteins, as well as proteins involved in signaling pathways, were identified, shedding light on the pathogenesis of HAM/TSP and potential therapeutic targets. Further experimental validation is needed to confirm the functional players proposed.

JOURNAL OF NEUROVIROLOGY (2021)

Article Biochemistry & Molecular Biology

Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts

Sharon L. Freshour et al.

Summary: The Drug-Gene Interaction Database (DGIdb) is a web resource that provides information on drug-gene interactions and druggable genes. DGIdb 4.0 is the latest major version release, featuring integration with crowdsourced efforts, addition of new sources, and updates to the data.

NUCLEIC ACIDS RESEARCH (2021)

Review Biochemistry & Molecular Biology

The potential role of miR-124-3p in tumorigenesis and other related diseases

Qian Li et al.

Summary: miR-124-3p is a microRNA that plays a significant regulatory role in various cancers. Although current research is incomplete, miR-124-3p shows potential importance as a clinical biomarker.

MOLECULAR BIOLOGY REPORTS (2021)

Article Oncology

Anti-tumor effect of trametinib in bladder cancer organoid and the underlying mechanism

Mohamed Elbadawy et al.

Summary: The study revealed that trametinib has anti-tumor effects on bladder cancer organoids, inhibiting cell viability even at low concentrations. Trametinib also induces differentiation of organoid cells from basal to luminal, suppressing tumor growth, and shows enhanced sensitivity in combination with YAP inhibitor or carboplatin.

CANCER BIOLOGY & THERAPY (2021)

Article Multidisciplinary Sciences

An immune cell infiltration-related gene signature predicts prognosis for bladder cancer

Hualin Chen et al.

Summary: By analyzing transcriptome data of BCa, a prognostic nomogram based on immune cell infiltration-related genes was successfully developed, including 5 prognostic immune cell infiltration-related module genes. This study provided potential prognostic indicators and immunotherapeutic targets for BCa.

SCIENTIFIC REPORTS (2021)

Article Oncology

LINC-PINT Inhibited Malignant Progression of Bladder Cancer by Targeting miR-155-5p

Xiancheng Han et al.

Summary: LINC-PINT expression is downregulated in bladder cancer tissues and cell lines, while miR-155-5p exhibits an opposite trend in bladder cancer tissues. Patients with low LINC-PINT expression have a lower five-year survival rate, and LINC-PINT is identified as a prognostic factor for bladder cancer. By targeting miR-155-5p, LINC-PINT inhibits the proliferation, invasion, and migration of bladder cancer cells.

CANCER MANAGEMENT AND RESEARCH (2021)

Review Oncology

Cancer Epigenetic Biomarkers in Liquid Biopsy for High Incidence Malignancies

Cora Palanca-Ballester et al.

Summary: In addition to genetic changes, cancer is also characterized by epigenetic alterations that can be used for diagnosis, prognosis, and predicting drug response. These changes can be detected in early stages of cancer and through liquid biopsies, offering valuable information for personalized treatment. Validation and standardization of epigenetic biomarkers are needed for their successful transfer from research to clinical practice.

CANCERS (2021)

Article Biotechnology & Applied Microbiology

Identification of prognostic and bone metastatic alternative splicing signatures in bladder cancer

Runzhi Huang et al.

Summary: This study constructed a predictive model based on ASEs and explored their molecular mechanism in BLCA bone metastasis, proposing a hypothesis that the splicing events of ITGB4 are regulated by the splicing factor JUP and may play a key role in BLCA bone metastasis through the glycosphingolipid biosynthesis ganglio series pathway.

BIOENGINEERED (2021)

Article Oncology

Screening key miRNAs and genes in prostate cancer by microarray analysis

Jianhui Wu et al.

TRANSLATIONAL CANCER RESEARCH (2020)

Article Oncology

A novel ETV6-miR-429-CRKL regulatory circuitry contributes to aggressiveness of hepatocellular carcinoma

Chunmei Guo et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)

Article Biochemistry & Molecular Biology

The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis

Natalia I. Diaz-Valdivia et al.

ONCOGENE (2020)

Review Medicine, Research & Experimental

Expression profile of microRNAs in bladder cancer and their application as biomarkers

Mohammad Taheri et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Oncology

MicroRNA Dysregulation and Non-Muscle-Invasive Bladder Cancer Prognosis

Angeline S. Andrew et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2019)

Review Biochemistry & Molecular Biology

Assessment of miR-98-5p, miR-152-3p, miR-326 and miR-4289 Expression as Biomarker for Prostate Cancer Diagnosis

Leire Moya et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Medicine, Research & Experimental

Joint bioinformatics analysis of underlying potential functions of hsa-let-7b-5p and core genes in human glioma

Xiaonan Xi et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2019)

Article Biochemistry & Molecular Biology

miR-93-5p may be an important oncogene in prostate cancer by bioinformatics analysis

Yuemei Yang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Article Oncology

Up-regulated expression of miR-155 in human colonic cancer

Hongliang Cao et al.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2018)

Article Biochemistry & Molecular Biology

TAM 2.0: tool for MicroRNA set analysis

Jianwei Li et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biotechnology & Applied Microbiology

SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells

Liu Yang et al.

ONCOTARGETS AND THERAPY (2018)

Article Cell Biology

miR-16-5p inhibits chordoma cell proliferation, invasion and metastasis by targeting

Hongliang Zhang et al.

CELL DEATH & DISEASE (2018)

Review Endocrinology & Metabolism

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

Jacob O'Brien et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Article Genetics & Heredity

Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosis

Da-nian Dai et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2017)

Article Multidisciplinary Sciences

Characterization of transcriptional modules related to fibrosing-NAFLD progression

Yi Lou et al.

SCIENTIFIC REPORTS (2017)

Article Oncology

Neoadjuvant dasatinib for muscle-invasive bladder cancer with tissue analysis of biologic activity

Noah M. Hahn et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2016)

Article Biotechnology & Applied Microbiology

Repression of the miR-93-enhanced sensitivity of bladder carcinoma to chemotherapy involves the regulation of LASS2

Jingyu Liu et al.

ONCOTARGETS AND THERAPY (2016)

Review Biochemistry & Molecular Biology

The role of MicroRNAs in human cancer

Yong Peng et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2016)

Review Chemistry, Multidisciplinary

Cancer biomarker detection: recent achievements and challenges

Li Wu et al.

CHEMICAL SOCIETY REVIEWS (2015)

Article Biochemistry & Molecular Biology

MicroRNA molecular profiling from matched tumor and bio-fluids in bladder cancer

David A. Armstrong et al.

MOLECULAR CANCER (2015)

Letter Biochemical Research Methods

miRWalk2.0: a comprehensive atlas of microRNA-target interactions

Harsh Dweep et al.

NATURE METHODS (2015)

Article Biochemistry & Molecular Biology

Let-7b-5p regulates proliferation and apoptosis in multiple myeloma by targeting IGF1R

Honghai Xu et al.

ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2014)

Article Cardiac & Cardiovascular Systems

MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts

Daren Wang et al.

CIRCULATION RESEARCH (2014)

Article Biochemistry & Molecular Biology

miR-98 suppresses melanoma metastasis through a negative feedback loop with its target gene IL-6

Fei Li et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2014)

Article Multidisciplinary Sciences

MiR-24 Promotes the Survival of Hematopoietic Cells

Tan Nguyen et al.

PLOS ONE (2013)

Article Oncology

Plasma microRNA profiles for bladder cancer detection

Liana Adam et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2013)

Article Oncology

Importin-α1 as a Novel Prognostic Target for Hepatocellular Carcinoma

Kenichiro Yoshitake et al.

ANNALS OF SURGICAL ONCOLOGY (2011)

Article Oncology

MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3

Li Huang et al.

INTERNATIONAL JOURNAL OF CANCER (2011)

Article Biochemistry & Molecular Biology

Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib

Paul W. Manley et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2010)

Article Pharmacology & Pharmacy

Stimulatory effects of the multi-kinase inhibitor sorafenib on human bladder cancer cells

A. Rose et al.

BRITISH JOURNAL OF PHARMACOLOGY (2010)

Review Pharmacology & Pharmacy

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy

Lawrence R. Dick et al.

DRUG DISCOVERY TODAY (2010)

Article Biochemistry & Molecular Biology

Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer

Saskia M. Wilting et al.

MOLECULAR CANCER (2010)

Article Biochemical Research Methods

WGCNA: an R package for weighted correlation network analysis

Peter Langfelder et al.

BMC BIOINFORMATICS (2008)

Article Oncology

Forced COX-2 expression induces PGE2 and invasion in immortalized urothelial cells

Jason Gee et al.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2008)

Article Biotechnology & Applied Microbiology

Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest

Wan Seok Yang et al.

GENOME BIOLOGY (2008)

Article Biochemical Research Methods

Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R

Peter Langfelder et al.

BIOINFORMATICS (2008)

Article Medicine, Research & Experimental

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

Michael R. Mancuso et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Oncology

Gene expression profiling of primary cutaneous melanoma and clinical outcome

VR Winnepenninckx et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)

Article Biochemistry & Molecular Biology

Epithelial growth factor-induced phosphorylation of caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells

L Orlichenko et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

A microRNA expression signature of human solid tumors defines cancer gene targets

S Volinia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Amplification and overexpression of E2F3 in human bladder cancer

A Feber et al.

ONCOGENE (2004)

Article Biochemistry & Molecular Biology

Cytoscape: A software environment for integrated models of biomolecular interaction networks

P Shannon et al.

GENOME RESEARCH (2003)

Review Multidisciplinary Sciences

The way things move: Looking under the hood of molecular motor proteins

RD Vale et al.

SCIENCE (2000)