4.7 Article

The optimal duration for the wrinkle test in a clinical setting

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SCIENTIFIC REPORTS
卷 12, 期 1, 页码 -

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NATURE PORTFOLIO
DOI: 10.1038/s41598-022-13083-7

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The study aimed to determine the time required for the wrinkle test in a clinical setting and the development of positive results among patients with complete laceration of a digital nerve. The results showed that when evaluating patients with digital nerve injury in a non-laboratory environment, the wrinkle test may require up to 40 minutes to obtain a positive result, and up to 25% of tests may produce false negative results if completed within the generally accepted time limit of 30 minutes.
To determine the time needed or the development of a positive result on the wrinkle test among patients with complete laceration of a digital nerve in a clinical setting. We prospectively recruited 20 patients who had undergone surgery for digital nerve laceration. The wrinkle test was conducted at a follow-up session up to 2 months after surgery, and the time to a positive wrinkling result was recorded. The wrinkle test was compared between the patient's injured versus uninjured contralateral finger. The average time required for a positive result on the wrinkle test was 24.5 min (+/- 11), with 25% patients requiring 40 min to obtain a positive result. When evaluating a patient with digital nerve injury in a non-laboratory environment, the wrinkle test may require up to 40 min to obtain a positive result. Our study suggests that if tests are completed following the generally accepted time limit reported in the literature (30 min), up to 25% of tests may produce false negative results.

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