4.7 Article

Comprehensive assessment of NR ligand polypharmacology by a multiplex reporter NR assay

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Toxicology

A comprehensive evaluation of anti-diabetic drugs on nuclear receptor PXR platform

Shashi Kala Singh et al.

TOXICOLOGY IN VITRO (2019)

Article Multidisciplinary Sciences

Evaluating biological activity of compounds by transcription factor activity profiling

Alexander Medvedev et al.

SCIENCE ADVANCES (2018)

Article Pharmacology & Pharmacy

The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPAR gamma in Xenopus tropicalis

Jingmin Zhu et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2017)

Article Biochemistry & Molecular Biology

Comparing the androgenic and estrogenic properties of progestins used in contraception and hormone therapy

Renate Louw-du Toit et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Nuclear Receptors, RXR, and the Big Bang

Ronald M. Evans et al.

Article Chemistry, Medicinal

Polypharmacology: Challenges and Opportunities in Drug Discovery

Andrew Anighoro et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson's Disease

Krista McFarland et al.

ACS CHEMICAL NEUROSCIENCE (2013)

Article Pharmacology & Pharmacy

THE CONCISE GUIDE TO PHARMACOLOGY 2013/14: NUCLEAR HORMONE RECEPTORS

Stephen P. H. Alexander et al.

BRITISH JOURNAL OF PHARMACOLOGY (2013)

Review Environmental Sciences

Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals

Daniel M. Rotroff et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2013)

Article Engineering, Environmental

Several Synthetic Progestins with Different Potencies Adversely Affect Reproduction of Fish

Tamsin J. Runnalls et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2013)

Review Pharmacology & Pharmacy

Nuclear Receptors and Their Selective Pharmacologic Modulators

Thomas P. Burris et al.

PHARMACOLOGICAL REVIEWS (2013)

Article Nutrition & Dietetics

Mechanisms of Action of (n-3) Fatty Acids

Philip C. Calder

JOURNAL OF NUTRITION (2012)

Article Biochemical Research Methods

Two Panels of Steroid Receptor Luciferase Reporter Cell Lines for Compound Profiling

David Sedlak et al.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2011)

Article Biochemistry & Molecular Biology

Current In Vitro High Throughput Screening Approaches to Assess Nuclear Receptor Activation

Judy L. Raucy et al.

CURRENT DRUG METABOLISM (2011)

Review Chemistry, Multidisciplinary

Orphan Nuclear Receptors as Targets for Drug Development

Subhajit Mukherjee et al.

PHARMACEUTICAL RESEARCH (2010)

Review Biochemistry & Molecular Biology

Network pharmacology: the next paradigm in drug discovery

Andrew L. Hopkins

NATURE CHEMICAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

T0901317 is a potent PXR ligand: Implications for the biology ascribed to LXR

Nico Mitro et al.

FEBS LETTERS (2007)

Article Endocrinology & Metabolism

Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates

Felix Grun et al.

MOLECULAR ENDOCRINOLOGY (2006)

Article Endocrinology & Metabolism

Environmental obesogens:: Organotins and endocrine disruption via nuclear receptor signaling

Felix Grun et al.

ENDOCRINOLOGY (2006)

Article Cell Biology

Synthetic progestins used in HRT have different glucocorticoid agonist properties

D Koubovec et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2005)

Article Biochemical Research Methods

Use of reporter cell lines for detection of endocrine-disrupter activity

P Willemsen et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand

PJ Willy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Biotechnology & Applied Microbiology

Principles for modulation of the nuclear receptor superfamily

H Gronemeyer et al.

NATURE REVIEWS DRUG DISCOVERY (2004)

Article Cell Biology

Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells

Å Wallén-Mackenzie et al.

GENES & DEVELOPMENT (2003)

Article Geriatrics & Gerontology

Classification and pharmacology of progestins

AE Schindler et al.

MATURITAS (2003)

Review Physiology

Nuclear receptors and the control of metabolism

GA Francis et al.

ANNUAL REVIEW OF PHYSIOLOGY (2003)

Article Multidisciplinary Sciences

4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor γ

P Coward et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Chemistry, Medicinal

Identification of a subtype selective human PPARα agonist through parallel-array synthesis

PJ Brown et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)