4.7 Article

The determinants of COVID-19 morbidity and mortality across countries

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SCIENTIFIC REPORTS
卷 12, 期 1, 页码 -

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NATURE PORTFOLIO
DOI: 10.1038/s41598-022-09783-9

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资金

  1. Ministry of Education (Singapore) [RG158/17, RT01/19]
  2. Ministry of Education (China) [18YJAZH004]
  3. National Science Foundation of China [72072067, 72132010]
  4. 111 Project [B20094]
  5. Beijing Outstanding Young Scientist Program [BJJWZYJH01201910034034]

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We have identified 21 predetermined country-level factors that explain the variations in weekly COVID-19 morbidity and mortality across 91 countries between January and the end of 2020. These factors include demographic-geographic factors, political-legal factors, socio-economic aspects, and healthcare factors. The male-to-female ratio, population density, and urbanization aggravate the severity of COVID-19, while education, temperature, and religious diversity mitigate its impact. Democracy and political corruption worsen the situation, but female leadership, strong legal systems, and public trust in government reduce infections and deaths. Socio-economic factors such as GDP per capita, income inequality, and happiness lead to worse outcomes. Interestingly, technological advancement increases morbidity but reduces mortality. SARS experience and healthcare infrastructure help countries perform better in combating the pandemic.
We identify 21 predetermined country-level factors that explain marked variations in weekly COVID-19 morbidity and mortality across 91 countries between January and the end of 2020. Besides factors commonly associated with infectious diseases (e.g., population and tourism activities), we discover a list of country characteristics that shape COVID-19 outcomes. Among demographic-geographic factors, the male-to-female ratio, population density, and urbanization aggravate the severity of COVID-19, while education, temperature, and religious diversity mitigate the impact of the pandemic on morbidity and mortality. For the political-legal dimension, democracy and political corruption are aggravating factors. In contrast, female leadership, the strength of legal systems, and public trust in government significantly reduce infections and deaths. In terms of socio-economic aspects, GDP per capita, income inequality, and happiness (i.e., life satisfaction) lead to worse COVID-19 outcomes. Interestingly, technology advancement increases morbidity but reduces mortality. For healthcare factors, SARS (severe acute respiratory syndrome) experience and healthcare infrastructure help countries perform better in combating the pandemic.

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