4.6 Article

Cubic Iron Core-Shell Nanoparticles Functionalized to Obtain High-Performance MRI Contrast Agents

期刊

MATERIALS
卷 15, 期 6, 页码 -

出版社

MDPI
DOI: 10.3390/ma15062228

关键词

nanomaterials; synthesis; magnetic properties; MRI contrast agents; toxicity; ROS

资金

  1. Estonian Ministry of Education and Research [IUT23-3, IUT23-7, IUT23-5, PUT1046, PUT210, PUT1015, PRG4]
  2. European Regional Development Fund [TK133, TK134]

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Nanoparticles with SiO2 coating and cubic iron core show high saturation magnetization, excellent biocompatibility, and potential for MRI contrast agents.
Nanoparticles with SiO2 coating were synthesized to have a cubic iron core. These were found to have saturation magnetization very close to the highest possible value of any iron-containing nanoparticles and the bulk iron saturation magnetization. The in vitro toxicology studies show that they are highly biocompatible and possess better MRI contrast agent potential than iron oxide NPs.

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