☆ 4.6 Review

Surface Engineering of Nanomaterials with Polymers, Biomolecules, and Small Ligands for Nanomedicine

MATERIALS (2022)

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Review Chemistry, Inorganic & Nuclear

Biomedical Applications of Functionalized Gold Nanoparticles: A Review

Kazem Nejati et al.

Summary: Metal nanoparticles, especially gold nanoparticles, have unique physicochemical properties that make them valuable for biomedical applications such as biosensing, cancer therapy, and drug delivery. Their large surface area allows for functionalization with biological molecules, making them a promising carrier for targeted drug delivery.

JOURNAL OF CLUSTER SCIENCE (2022)

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Review Polymer Science

A review of protein adsorption and bioactivity characteristics of poly ε-caprolactone scaffolds in regenerative medicine

Abdalla Abdal-hay et al.

Summary: PCL scaffolds have great potential in tissue engineering, but their biological activity and surface wettability are limited. Scaffold manipulations can enhance protein adsorption and achieve optimized biocompatibility.

EUROPEAN POLYMER JOURNAL (2022)

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Review Chemistry, Analytical

Synergizing Functional Nanomaterials with Aptamers Based on Electrochemical Strategies for Pesticide Detection: Current Status and Perspectives

Mansour Mahmoudpour et al.

Summary: This study highlights the recent development and promising applications of functional nanomaterials with aptamers for pesticide detection based on electrochemical strategies, as well as the research on novel aptamer-functionalized microdevices for the portability of pesticide sensors. The major challenges and future prospects in this field are also discussed to provide ideas for further research.

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY (2022)

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Review Chemistry, Multidisciplinary

Novel insights into nanomaterials for immunomodulatory bone regeneration

Ya Cui et al.

Summary: By manipulating the composition and structure of nanomaterials, an immunomodulatory bone regeneration strategy can be achieved to accelerate osteogenesis. However, the lack of knowledge about the interaction between nanomaterials and the immune system has resulted in their underutilization in clinical trials.

NANOSCALE ADVANCES (2022)

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Review Biochemical Research Methods

Application of nanotechnology in medical diagnosis and imaging

Amit Singh et al.

Summary: Nanotechnology has greatly impacted the advancement in disease imaging, early detection, diagnosis, and prognosis. The unique properties of nanoparticles enable contrast enhancement for biomedical imaging and molecular level tissue-specific diagnosis. Small variations in nanoparticle size or composition can result in significant changes in their optical, magnetic, or electrical properties, allowing for unique possibilities of multiplexing.

CURRENT OPINION IN BIOTECHNOLOGY (2022)

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Article Biochemistry & Molecular Biology

Novel nanocomposite scaffold based on gelatin/PLGA-PEG-PLGA hydrogels embedded with TGF-β1 for chondrogenic differentiation of human dental pulp stem cells in vitro

Parisa Ghandforoushan et al.

Summary: A novel nanocomposite hydrogel scaffold composed of natural-based gelatin and synthetic-based triblock copolymer was developed and loaded with TGF-beta 1. The scaffold showed promising effects on promoting adhesion, viability, and chondrogenic differentiation of hDPSCs.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

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Review Materials Science, Ceramics

One-dimensional electrospun ceramic nanomaterials and their sensing applications

Yuting Wang et al.

Summary: One-dimensional sensing materials prepared via electrospinning exhibit intrinsic properties and great potential for applications in electronic sensing devices. By reviewing different structural and functional characteristics of ceramic materials and discussing their applications and future development directions, the performance of these materials can be enhanced.

JOURNAL OF THE AMERICAN CERAMIC SOCIETY (2022)

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Article Polymer Science

Broad-Spectrum Theranostics and Biomedical Application of Functionalized Nanomaterials

Meshal Alshamrani

Summary: This article discusses the application of nanomaterials in the field of medicine, focusing on the crucial role of nanoparticles in drug therapy. The article introduces different types of nanoparticles and their conjugation with biomolecules, and explores the application areas of nanomaterials in disease diagnosis and treatment, including bio-imaging, drug delivery, biosensing, and tissue engineering.

POLYMERS (2022)

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Article Chemistry, Multidisciplinary

LbL Nano-Assemblies: A Versatile Tool for Biomedical and Healthcare Applications

Ana M. Diez-Pascual et al.

Summary: This review provides an overview of polyelectrolytes (PEs) research and applications. PE films prepared by layer-by-layer (LbL) approach offer precise control over properties and have wide biomedical applications. The review highlights the design and fabrication research of nanofilms and discusses their applications in the biomedical field.

NANOMATERIALS (2022)

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Review Pharmacology & Pharmacy

Hard, Soft, and Hard-and-Soft Drug Delivery Carriers Based on CaCO3 and Alginate Biomaterials: Synthesis, Properties, Pharmaceutical Applications

Yanqi Huang et al.

Summary: This article introduces the characteristics and applications of inorganic calcium carbonate particles and organic alginate hydrogels as drug delivery carriers, as well as hybrid structures containing both types of carriers. It proposes the rational combination of these two carrier types to enhance their performance, and discusses their similarities and differences.

PHARMACEUTICS (2022)

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Article Chemistry, Physical

Surface functionalization of graphene oxide with tannic acid: Covalent vs non-covalent approaches

Carlos Sainz-Urruela et al.

Summary: Graphene oxide (GO) has attracted significant interest in material science, biomedicine, and biotechnology due to its exceptional physical properties and surface functionalization capacity. In this study, a simple and environmentally friendly method was developed to prepare surface-functionalized GO nanosheets using tannic acid (TA) as a biological macro-molecule. The covalent grafting of TA improved the hydrophobicity and dispersion of GO in organic solvents, while also acting as a crosslinker to enhance thermal stability and antibacterial properties. This research emphasizes the potential of TA for the exfoliation and functionalization of GO, as well as its applications in biomedicine and the development of green nanocomposites.

JOURNAL OF MOLECULAR LIQUIDS (2022)

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Article Polymer Science

Directing Axonal Growth: A Review on the Fabrication of Fibrous Scaffolds That Promotes the Orientation of Axons

Devindraan Sirkkunan et al.

Summary: This review discusses the construction of neural scaffolds, with a focus on cellular orientation and axonal alignment of neural cells within the extracellular matrix. A better understanding of these mechanisms can provide insights into the rationale for creating scaffolds with specific functionality.

GELS (2022)

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Article Chemistry, Physical

A novel luminescence sensor based on porous molecularly imprinted polymer-ZnS quantum dots for selective recognition of paclitaxel

Jianwei Bai et al.

Summary: A molecularly imprinted fluorescent sensor was successfully constructed for selective recognition of PTX by introducing M-POSS to add porous structure, showing good binding properties and selectivity with potential applications.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

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Review Chemistry, Multidisciplinary

Peptide-functionalized liposomes as therapeutic and diagnostic tools for cancer treatment

Jafrin Jobayer Sonju et al.

Summary: This review focuses on recent advances in peptide-functionalized liposomal formulation techniques in cancer diagnosis and treatment, highlighting the benefits and current challenges of these novel techniques.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Polymer Science

Copolymer/graphene oxide nanocomposites as potential anticancer agents

Abbas Rahdar et al.

Summary: A synthetic method was used to prepare graphene oxide/poly(ethyleneglycol)-b-poly(2-hydroxyethyl methacrylate-g-lactide)(2) nanocomposites, which showed potential for cancer therapy.

POLYMER BULLETIN (2021)

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Article Cell & Tissue Engineering

Nonviral Gene Delivery Embedded in Biomimetically Mineralized Matrices for Bone Tissue Engineering

Timothy M. Acri et al.

Summary: Research in bone tissue engineering has shown that optimizing the ratio of growth factors in gene-activated matrices combined with biomimetic mineralization can significantly improve bone regeneration outcomes. Embedding gene delivery within a mineral layer formed from simulated body fluid immersion can enhance bone formation rates, highlighting a promising approach for future optimization of synthetic gene activated matrices.

TISSUE ENGINEERING PART A (2021)

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Article Chemistry, Multidisciplinary

Aptamer-Dendrimer Functionalized Magnetic Nano-Octahedrons: Theranostic Drug/Gene Delivery Platform for Near-Infrared/Magnetic Resonance Imaging-Guided Magnetochemotherapy

Zhongyuan Chen et al.

Summary: A highly selective theranostic nanocomplex, ZIPP-Apt:DOX/siHSPs, combining magnetic hyperthermia and chemotherapy, can enhance cellular uptake and tumor-specific accumulation, potentially advancing versatile magnetic nanosystems towards clinical applications.

ACS NANO (2021)

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Article Chemistry, Applied

Synthesis of functionalized silk-coated chitosan-gold nanoparticles and microparticles for target-directed delivery of antitumor agents

Himali Horo et al.

Summary: Research demonstrates that functionalized silk coating can enhance cellular uptake of nanoparticles, making them potential drug delivery tools.

CARBOHYDRATE POLYMERS (2021)

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Article Chemistry, Multidisciplinary

Versatile Surface Functionalization of Water-Dispersible Iron Oxide Nanoparticles with Precisely Controlled Sizes

Pohlee Cheah et al.

Summary: This paper presents a facile one-pot strategy for versatile surface functionalization and precise size control of iron oxide nanoparticles, which can be applied in biomedical fields. The synthesis method allows surface modification with different coating materials to introduce new surface functionalities. The nanoparticles with surface ligands exhibit outstanding stability and improved sensitivity in aqueous solution, showing potential for biological applications.

LANGMUIR (2021)

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Article Environmental Sciences

DNA damage and ovarian ultrastructural lesions induced by nickel oxide nano-particles in Blaps polycresta (Coleoptera: Tenebrionidae)

Dalia Abdel Moneim Kheirallah et al.

Summary: The study investigated the effects of NiO-NPs on the ovarian tissues of ground beetles, showing that NiO-NPs can induce DNA damage and cellular toxicity, leading to chromatin condensation and lysosome accumulation. This highlights the potential genotoxic effects of NiO-NPs on female insect gonads and suggests the need for further research on intracellular ROS generation.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

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Review Biochemistry & Molecular Biology

State of the Art in the Antibacterial and Antiviral Applications of Carbon-Based Polymeric Nanocomposites

Ana M. Diez-Pascual

Summary: Carbon nanomaterials, with their exceptional properties, have great potential for antibacterial applications, but challenges such as poor dispersibility and cost need to be addressed before full exploration. Integrating carbon nanomaterials within antimicrobial polymeric matrices is one way to overcome these challenges. Research in this area is ongoing and has the potential to expand into various application fields.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Biochemistry & Molecular Biology

Active Targeted Nanoparticles for Delivery of Poly(ADP-ribose) Polymerase (PARP) Inhibitors: A Preliminary Review

Saman Sargazi et al.

Summary: Nanotechnology has revolutionized drug delivery strategies, improving the efficacy of PARP inhibitors for cancer therapy. Recent advances in nanotechnology have significantly enhanced the effectiveness of PARP inhibitors.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Pharmacology & Pharmacy

Stimuli-responsive nanoliposomes as prospective nanocarriers for targeted drug delivery

Muhammad Bilal et al.

Summary: This review discusses the advantages and mechanisms of nanoliposomes for targeted drug delivery, as well as the stimulation-responsive targeting approaches for efficient cancer therapy. Various targeting strategies and challenges associated with these systems are also detailed in this review.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

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Review Chemistry, Medicinal

Silica-Based Bioactive Glasses and Their Applications in Hard Tissue Regeneration: A Review

Nuha Al-Harbi et al.

Summary: Regenerative medicine aims to improve tissue repair and restoration processes using bioactive materials like bioactive glass, which is mainly used for bone tissue regeneration. The bioactivity of bioactive glass depends on compositional ratio, and manipulating the content ratio can develop other types of bioactive glasses with controllable chemical durability and affinity with bone.

PHARMACEUTICALS (2021)

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Review Nanoscience & Nanotechnology

Functional Aptamer-Embedded Nanomaterials for Diagnostics and Therapeutics

Sitao Xie et al.

Summary: The combination of nanomaterials and aptamers holds great potential in bioapplications, especially in the fields of diagnostics and therapeutics, with important applications in cellular analysis, imaging, targeted drug delivery, and cancer diagnosis/therapy.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Chemistry, Physical

Silica coating of iron oxide magnetic nanoparticles by reverse microemulsion method and their functionalization with cationic polymer P (NIPAm-co-AMPTMA) for antibacterial vancomycin immobilization

Jannatun Nayeem et al.

Summary: In this study, a new approach was developed to improve the stability of iron oxide nanoparticles (IONPs) and their interactions with drug molecules by surface modification with poly[N-isopropylacrylamide-co-(3-acrylamidopropyl) trimethylammonium chloride]. The resulting thermally sensitive magnetic nanocomposites (MNCs) showed promising potential for biomedical applications, as demonstrated by the successful immobilization of antibacterial vancomycin and inhibition of bacterial growth.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

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Article Chemistry, Physical

Transferrin-functionalized liposomes for docetaxel delivery to prostate cancer cells

Mariza Aires Fernandes et al.

Summary: This study investigated the delivery of docetaxel to prostate cancer cells using transferrin-functionalized liposomes. Results showed that these systems had small and stable size, with higher toxicity towards PC-3 cells. Confocal microscopy confirmed successful internalization of functionalized liposomes in PC-3 cells, while interaction with transferrin receptors was further validated using Quartz Crystal Microbalance with Dissipation technology. Further studies are needed to explore the potential of these systems in three-dimensional cell models and in vivo xenograft studies.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2021)

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Review Energy & Fuels

Preparation, Functionalization, Modification, and Applications of Nanostructured Gold: A Critical Review

Muhammad Yaseen et al.

Summary: Gold nanoparticles play a significant role in science and technology due to their unique properties and potential applications. Various approaches for synthesis, modification and functionalization of nanostructured gold have been discussed in detail in this review. Modification and functionalization of nanostructured gold have shown to enhance catalytic performance, summarizing various methods for better catalytic outcomes.

ENERGIES (2021)

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Article Chemistry, Physical

Effect of surface functionalization on the heating efficiency of magnetite nanoclusters for hyperthermia application

Molongnenla Jamir et al.

Summary: The effect of surface functionalization on Fe3O4 assembled nanoclusters with biopolymers was studied. The results showed that surface functionalization significantly enhanced specific absorption rate, indicating potential for hyperthermia applications.

JOURNAL OF ALLOYS AND COMPOUNDS (2021)

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Article Chemistry, Analytical

Novel paper- and fiber optic-based fluorescent sensor for glucose detection using aniline-functionalized graphene dots

Tran Van Tam et al.

Summary: Aniline functionalized graphene quantum dots (a-GQDs) are synthesized and modulated with phenyl boric acid (PBA) for glucose detection, demonstrating high sensitivity and selectivity. The paper-based fluorescent sensor using a-GQDs ink is prepared for portable devices, while the aGQDs/hydrogel film is evaluated for wearable and fiber optic-based sensors, exhibiting remarkable performance in glucose detection with excellent recyclability. Furthermore, the a-GQD/PBA system shows excellent biocompatibility in detecting glucose in HeLa cells, providing a novel approach for developing low-cost and flexible sensors for the portable and visual detection of glucose.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Review Chemistry, Physical

Functionalization of Ruthenium Olefin-Metathesis Catalysts for Interdisciplinary Studies in Chemistry and Biology

Takashi Matsuo

Summary: This review article discusses the application of designed Hoveyda-Grubbs-type complexes in bio-relevant studies, addressing issues and strategies when used in aqueous media, and controlling the reactivities of the complexes through structural modification. It also introduces a recent finding on the ruthenium complex transfer reaction between Hoveyda-Grubbs-type complexes and biomolecules.

CATALYSTS (2021)

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Article Chemistry, Physical

Tresca Stress Simulation of Metal-on-Metal Total Hip Arthroplasty during Normal Walking Activity

Muhammad Imam Ammarullah et al.

Summary: The study analyzed the Tresca stress of metal-on-metal bearings in total hip arthroplasty with different materials, finding that titanium alloy exhibited the best performance in reducing stress compared to cobalt chromium molybdenum and stainless steel 316L.

MATERIALS (2021)

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Article Pharmacology & Pharmacy

Functionalization of Gold Nanostars with Cationic β-Cyclodextrin-Based Polymer for Drug Co-Loading and SERS Monitoring

Orlando Donoso-Gonzalez et al.

Summary: Gold nanostars functionalized with cationic beta-cyclodextrin-based polymer (CCD/P) to load phenylethylamine and piperine were characterized and evaluated for potential biomedical applications. The system showed improved colloidal stability and high loading capacity, making it suitable for drug delivery and SERS-based detection.

PHARMACEUTICS (2021)

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Review Medicine, Research & Experimental

Nanotechnology shaping stem cell therapy: Recent advances, application, challenges, and future outlook

Yongqiang Dong et al.

Summary: Stem cell nanotechnology, an emerging field, has made significant progress in experimental studies, confirming the importance of nanotechnology in stem cell therapies. The structure and properties of nanomaterials impact the proliferation and differentiation of stem cells, leading to a new interdisciplinary frontier in material science and regenerative medicine.

BIOMEDICINE & PHARMACOTHERAPY (2021)

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Article Chemistry, Multidisciplinary

A Multifunctional Polymeric Micelle for Targeted Delivery of Paclitaxel by the Inhibition of the P-Glycoprotein Transporters

Sobia Razzaq et al.

Summary: This study focuses on overcoming multidrug resistance in cancer chemotherapy by delivering paclitaxel specifically to target sites with enhanced efficacy against solid tumors. The use of multifunctional polymeric micelles for loading and releasing paclitaxel has shown significant improvements in permeation, apoptosis induction, biodistribution, and toxicity reduction. By targeting the P-glycoprotein efflux pump, the mucopermeating PT-R-Ms demonstrated a promising approach to improve cancer therapy outcomes.

NANOMATERIALS (2021)

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Review Chemistry, Multidisciplinary

Amino Acids, Peptides, and Proteins: Implications for Nanotechnological Applications in Biosensing and Drug/Gene Delivery

Simge Er et al.

Summary: Amino acids play a crucial role in biochemical research, transforming nanotechnology through protein, peptide, and amino acid-based drug delivery systems. Novel nanostructures like carbon nanotubes and metal-based nanoparticles are utilized as nanosensors for accurate detection of organic compounds. Protein-based nanocarriers are emerging as effective drug and gene delivery platforms, addressing biological barriers and enhancing delivery efficacy.

NANOMATERIALS (2021)

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Review Chemistry, Multidisciplinary

Novel Perspectives towards RNA-Based Nano-Theranostic Approaches for Cancer Management

Rabia Arshad et al.

Summary: The development of multi-functional nanoparticles and nano-biosensors has revolutionized cancer diagnosis and treatment by attaching biocompatible ligands to over-expressed cancer tissues, allowing for targeted action. Advancements in modifying molecular genetics for personalized and targeted treatments using RNA interference have become a key breakthrough in cancer therapy.

NANOMATERIALS (2021)

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Review Biochemistry & Molecular Biology

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

Carlos Sainz-Urruela et al.

Summary: Graphene and its derivatives have become important nanomaterials in the field of optical and electrochemical sensors due to their unique physical and chemical properties, facilitating the design of highly selective and sensitive sensors. Their presence of oxygen functional groups allows them to be easily combined with different types of inorganic nanoparticles to yield nanocomposites with enhanced sensitivity for sensor applications. Their synthesis process, functionalization routes, main properties, and challenges are summarized, providing insights on the advantages offered by graphene and its derivatives for the detection of bioactive compounds.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Biochemistry & Molecular Biology

Functionalized Reduced Graphene Oxide as a Versatile Tool for Cancer Therapy

Banendu Sunder Dash et al.

Summary: Nanomedicine using carbon-based nanomaterials, especially reduced graphene oxide (rGO), has shown promising potential in cancer therapy due to its ability to carry drugs and act as a photothermal agent. Functionalized rGO can be designed as multifunctional nanosystems with temperature/pH-dependent drug/gene delivery abilities for multimodal cancer therapy. Additional advantages like high biocompatibility, targeted delivery, and enhanced photothermal effects further enhance the potential of functionalized rGO in cancer treatment.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Chemistry, Analytical

Aptamer-functionalized Au nanoparticles array as the effective SERS biosensor for label-free detection of interleukin-6 in serum

Muhammad Muhammad et al.

Summary: This study successfully developed a label-free biosensor for detecting interleukin-6 and achieved quantitative evaluation in a low concentration range. The research indicates that the aptamer-based SERS biosensor can be a promising tool for quick and convenient medical diagnosis applications.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Chemistry, Multidisciplinary

A Hyaluronic Acid Functionalized Self-Nano-Emulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection

Rabia Arshad et al.

Summary: The hyaluronic acid-functionalized self-nano emulsifying drug delivery system (HA-CIP-SNEDDS) effectively improved the biopharmaceutical parameters of CIP, demonstrating enhanced permeation ability through goat intestinal mucus. Compared to free CIP, HA-CIP-SNEDDS exhibited stronger anti-biofilm activity, improved biocompatibility, and enhanced oral pharmacokinetics.

NANOMATERIALS (2021)

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Article Nanoscience & Nanotechnology

Multifunctional Cellulose Nanopaper with Superior Water-Resistant, Conductive, and Antibacterial Properties Functionalized with Chitosan and Polypyrrole

Haishun Du et al.

Summary: The study successfully improved the water resistance of cellulose nanopaper by impregnating it with chitosan and in situ polymerizing polypyrrole, achieving excellent mechanical strength and multifunctional properties in the process.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Review Chemistry, Multidisciplinary

Graphene-based materials for environmental applications: a review

V Karthik et al.

Summary: The recent discovery and synthesis of graphene materials have resulted in a variety of applications in fields such as medicine, energy, and the environment. This review focuses on the synthesis, functionalization, properties, and applications of graphene materials, particularly in environmental uses such as pollutant detection, adsorption, and photocatalysis. Graphene-based materials demonstrate high adsorption capacities for metal ions and organic pollutants, with graphene oxide-based photocatalytic devices achieving over 95% dye degradation.

ENVIRONMENTAL CHEMISTRY LETTERS (2021)

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Editorial Material Biochemistry & Molecular Biology

Carbon-Based Nanomaterials

Ana Maria Diez-Pascual

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Medicine, Research & Experimental

Quercetin-loaded F127 nanomicelles: Antioxidant activity and protection against renal injury induced by gentamicin in rats

Abbas Rahdar et al.

Summary: Quercetin was formulated into microemulsions to improve bioavailability, with the nanoencapsulated form showing potential in protecting against gentamicin-induced renal oxidative stress and kidney damage in a rat model of nephrotoxicity. Further evaluations are warranted.

LIFE SCIENCES (2021)

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Review Chemistry, Multidisciplinary

Aptamer functionalized nanomaterials for biomedical applications: Recent advances and new horizons

Mansour Mahmoudpour et al.

Summary: This review discusses the design and applications of aptamer functionalized nanomaterials (AFMs) in the biomedical field, including synthesis strategies, versatile roles of nanomaterials, and representative examples of biomedical applications. Challenges and opportunities in this emerging field are also presented.

NANO TODAY (2021)

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Article Environmental Sciences

Pre-coating of protein modulate patterns of corona formation, physiological stability and cytotoxicity of silver nanoparticles

Arpit Bhargava et al.

Summary: Protein pre-coating on silver nanoparticles surface reduces further protein binding significantly. Corona formation on pristine nanoparticles significantly improves their stability in the biological medium. Cell-based experiments show that the binding, uptake, and toxicity of nanoparticles in different cell lines are directly linked to their physiological stability due to corona formation.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

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Article Chemistry, Multidisciplinary

Design of Mannose-Coated Rifampicin nanoparticles modulating the immune response and Rifampicin induced hepatotoxicity with improved oral drug delivery

Aisha Rauf et al.

Summary: The preactivated thiolated chitosan nanoparticles show enhanced in vivo oral efficacy and hepatoprotective effects for tuberculosis treatment, with significantly improved permeation and oral bioavailability compared to conventional formulations. Additionally, the nanoparticles provide immunomodulation and improve liver function through modulation of gene expression levels and markers of oxidative stress.

ARABIAN JOURNAL OF CHEMISTRY (2021)

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Article Multidisciplinary Sciences

A pseudohomogeneous nanocarrier based on carbon quantum dots decorated with arginine as an efficient gene delivery vehicle

Aram Rezaei et al.

Summary: Pseudohomogeneous carrier refers to carbon-based vehicle with high interaction ability for genetic materials, chitosan and arginine-decorated CQDs can form stable carboplex for gene inhibition or expression, showing potential for gene therapy applications.

SCIENTIFIC REPORTS (2021)

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Article Polymer Science

Effect of Graphene Oxide on the Properties of Poly(3-Hydroxybutyrate-co-3-Hydroxyhexanoate)

Ana M. Diez-Pascual

Summary: PHB, a biodegradable and biocompatible polymer, has low thermal stability, poor impact resistance and lacks antibacterial activity. Blending with other biodegradable polymers to form PHBHHx can improve these issues, however, PHBHHx shows reduced stiffness and poorer barrier properties. To enhance the properties, researchers prepared biodegradable PHBHHx/GO nanocomposites via a solvent casting method, which showed increased mechanical properties and antibacterial activity, offering new perspectives for food packaging.

POLYMERS (2021)

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Review Polymer Science

Development of Graphene-Based Polymeric Nanocomposites: A Brief Overview

Ana M. Diez-Pascual

Summary: Graphene and its derivatives, when combined with polymers, form novel nanocomposites with enhanced properties, making them useful in various fields such as biomedicine, electronics, and energy storage. Functionalization methods have been utilized to improve the interaction between these nanocomposites and polymers.

POLYMERS (2021)

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Article Chemistry, Multidisciplinary

Environmentally Safe Biosynthesis of Gold Nanoparticles Using Plant Water Extracts

Mohadeseh Hassanisaadi et al.

Summary: This study evaluated 109 plant species from traditional medicine in Middle Eastern countries as new sources for AuNPs, with 37 new plant species identified. 102 extracts from 117 plant parts were able to bioreduce Au3+ to Au-0 using water extraction methods. The biosynthesized AuNPs from six plants showed color changes and varied in sizes from 27 to 107 nm.

NANOMATERIALS (2021)

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Article Pharmacology & Pharmacy

New Nanomaterials with Intrinsic Antioxidant Activity by Surface Functionalization of Niosomes with Natural Phenolic Acids

Elisabetta Mazzotta et al.

Summary: In this study, a new family of nanoantioxidants was developed by covalently grafting phenolic acids onto the surfaces of Tween 80 niosomes, showing improved stability and biocompatibility. The antioxidant activity of the vesicles was enhanced when functionalized with FR or GA, and a synergic effect of CUR combined with GA and CF was observed in scavenging ABTS and DPPH radicals.

PHARMACEUTICS (2021)

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Article Medicine, Research & Experimental

A therapeutic cancer vaccine delivers antigens and adjuvants to lymphoid tissues using genetically modified T cells

Joshua R. Veatch et al.

Summary: The study explores the use of gene-modified T cells as a vaccine platform, with Tvax effectively inducing potent T cell responses to tumor antigens. The design of the vaccine, utilizing a combination of signals and co-expression of IL-12 and GM-CSF, enhances the immune activity of T cells. Tvax shows anti-tumor activity in preclinical mouse models, providing a potential pathway for translating this therapeutic platform to clinical cancer treatment.

JOURNAL OF CLINICAL INVESTIGATION (2021)

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Article Materials Science, Biomaterials

Encapsulation and controlled release of an antimalarial drug using surface functionalized mesoporous silica nanocarriers

Haruka Hirayama et al.

Summary: In this study, encapsulation and release of antimalarial drug quinine using three nanocarriers were investigated, with pH and thermal optimization effects on drug adsorption and release from the nanocarriers explored.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Review Chemistry, Multidisciplinary

Applications of nanomaterials in tissue engineering

Xinmin Zheng et al.

Summary: Recent advances in nanotechnology have brought significant benefits in tissue engineering, supporting the repair and reconstruction of damaged tissues or organs and the design of smart drug delivery systems. The choice of appropriate nanomaterials is crucial for different tissue engineering applications due to tissue heterogeneity. This review mainly focuses on the use of nanomaterials in tissue engineering, discussing their characteristics, preparation methods, application progress, and future prospects.

RSC ADVANCES (2021)

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Article Nanoscience & Nanotechnology

Phase Transfer of Hydrophobic Nanoparticles Functionalized with Zwitterionic Bisphosphonate Ligands for Renal-Clearable Imaging Nanoprobes

Hao Li et al.

Summary: Renal clearance of inorganic nanoparticles is important for their clinical use, but current methods involving hydrophilic molecules for surface modification can hinder urinary excretion. A new approach using zwitterionic bisphosphonate (ZBP) ligands can efficiently replace hydrophobic ligands on nanoparticles, leading to biocompatible surfaces with minimal hydrodynamic size and improved stability. This ZBP-based phase transfer method shows promise for providing imaging nanoprobes with high biosafety for clinical applications.

ACS APPLIED NANO MATERIALS (2021)

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Review Materials Science, Biomaterials

Hollow iron oxide nanomaterials: synthesis, functionalization, and biomedical applications

Ruixue Wei et al.

Summary: Hollow iron oxide nanoparticles are a promising class of nanostructures with low toxicity, good biocompatibility, and intrinsic magnetic properties, making them attractive in biomedical applications. Various strategies for synthesis, surface functionalization, and biomedical applications of hollow iron oxide nanoparticles have been reviewed, highlighting their potential in magnetic resonance imaging, drug delivery, and cancer therapy. Prospects for further development of hollow iron oxide nanoparticles have also been discussed.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Chemistry, Multidisciplinary

Progress in natural polymer engineered biomaterials for transdermal drug delivery systems

V. S. Sivasankarapillai et al.

Summary: Research focuses on the development of transdermal drug delivery systems, as well as the application of important biopolymers in this field. The advantages and limitations of topical drug delivery methods, as well as three common biopolymers such as natural rubber, chitosan, and cellulose, are extensively analyzed.

MATERIALS TODAY CHEMISTRY (2021)

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Article Environmental Sciences

Advances in nanomedical applications: diagnostic, therapeutic, immunization, and vaccine production

Amr El-Sayed et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020)

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Review Chemistry, Multidisciplinary

Piezoelectric Nano-Biomaterials for Biomedicine and Tissue Regeneration

Kausik Kapat et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

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Review Environmental Sciences

Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool

Jobin Jose et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020)

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Review Dentistry, Oral Surgery & Medicine

Effect of the nano/microscale structure of biomaterial scaffolds on bone regeneration

Lisha Zhu et al.

INTERNATIONAL JOURNAL OF ORAL SCIENCE (2020)

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Review Chemistry, Multidisciplinary

Metal-Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Pooyan Makvandi et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

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Article Chemistry, Physical

Fabrication of palladium nanoparticles anchored polypyrrole functionalized reduced graphene oxide nanocomposite for antibiofilm associated orthopedic tissue engineering

Murugesan Balaji et al.

APPLIED SURFACE SCIENCE (2020)

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Article Biochemistry & Molecular Biology

Synthesis of micelles based on chitosan functionalized with gold nanorods as a light sensitive drug delivery vehicle

Ali Pourjavadi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Review Biochemistry & Molecular Biology

Antibacterial Action of Nanoparticle Loaded Nanocomposites Based on Graphene and Its Derivatives: A Mini-Review

Ana Maria Diez-Pascual

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Review Biotechnology & Applied Microbiology

Bio-Fabrication: Convergence of 3D Bioprinting and Nano-Biomaterials in Tissue Engineering and Regenerative Medicine

Nicola Di Marzio et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

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Article Biochemistry & Molecular Biology

Folic acid functionalized starch encapsulated green synthesized copper oxide nanoparticles for targeted drug delivery in breast cancer therapy

Arokia Vijaya Anand Mariadoss et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Article Pharmacology & Pharmacy

The Effects of Polymer Coating of Gold Nanoparticles on Oxidative Stress and DNA Damage

Gamze Tilbe Sen et al.

INTERNATIONAL JOURNAL OF TOXICOLOGY (2020)

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Review Pharmacology & Pharmacy

Advances in nanotechnology and nanomaterials based strategies for neural tissue engineering

Raj Kumar et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

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Article

Review: Organic nanoparticle based active targeting for photodynamic therapy treatment of breast cancer cells

Hanieh Montaseri et al.

Oncotarget (2020)

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Article Chemistry, Physical

Risk Management Framework for Nano-Biomaterials Used in Medical Devices and Advanced Therapy Medicinal Products

Elisa Giubilato et al.

MATERIALS (2020)

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Review Biotechnology & Applied Microbiology

Nanostructured Biomaterials for Bone Regeneration

Joseph G. Lyons et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

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Review Biochemistry & Molecular Biology

Nanoparticle Surface Functionalization: How to Improve Biocompatibility and Cellular Internalization

Gennaro Sanita et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2020)

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Review Chemistry, Multidisciplinary

Lignin Functionalization for the Production of Novel Materials

Stefania Bertella et al.

TRENDS IN CHEMISTRY (2020)

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Article Chemistry, Multidisciplinary

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Plinio Innocenzi et al.

CHEMICAL SCIENCE (2020)

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Review Materials Science, Biomaterials

Functionalization of Polymers and Nanomaterials for Biomedical Applications: Antimicrobial Platforms and Drug Carriers

Masoud Delfi et al.

PROSTHESIS (2020)

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Article Biochemistry & Molecular Biology

Preparation of an Electrically Conductive Graphene Oxide/Chitosan Scaffold for Cardiac Tissue Engineering

Lili Jiang et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2019)

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Article Multidisciplinary Sciences

pH-responsive and targeted delivery of curcumin via phenylboronic acid-functionalized ZnO nanoparticles for breast cancer therapy

Mousumi Kundu et al.

JOURNAL OF ADVANCED RESEARCH (2019)

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Article Materials Science, Multidisciplinary

Investigation of the effect of graphene oxide functionalization on the physical, mechanical and shape memory properties of polyurethane/reduced graphene oxide nanocomposites

Reza Lotfi Mayan Sofia et al.

DIAMOND AND RELATED MATERIALS (2019)

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Article Biochemistry & Molecular Biology

Graphene oxide containing chitosan scaffolds for cartilage tissue engineering

Mohammad Amin Shamekhi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

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Article Chemistry, Multidisciplinary

Structural and Physicochemical Properties and Biocompatibility of Linear and Looped Polymer-Capped Gold Nanoparticles

Yanqiu Du et al.

LANGMUIR (2019)

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Editorial Material Polymer Science

Nanoparticle Reinforced Polymers

Ana Maria Diez-Pascual

POLYMERS (2019)

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Review Oncology

Active Targeting Strategies Using Biological Ligands for Nanoparticle Drug Delivery Systems

Jihye Yoo et al.

CANCERS (2019)

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Article Nanoscience & Nanotechnology

Hyaluronic acid-modified mesoporous silica-coated superparamagnetic Fe3O4 nanoparticles for targeted drug delivery

Zhengzou Fang et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

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Article Biophysics

Therapeutic and diagnostic potential of nanomaterials for enhanced biomedical applications

M. Abd Elkodous et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

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Article Biochemistry & Molecular Biology

Functionalization of carbon nanotubes with chitosan based on MALI multicomponent reaction for Cu2+ removal

Jibo Dou et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

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Article Nanoscience & Nanotechnology

Size- and cell type-dependent cellular uptake, cytotoxicity and in vivo distribution of gold nanoparticles

Qiyue Xia et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

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Review Nanoscience & Nanotechnology

Capping gold nanoparticles with albumin to improve their biomedical properties

Karen Bolanos et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

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Review Pharmacology & Pharmacy

Targeted magnetic iron oxide nanoparticles: Preparation, functionalization and biomedical application

Abeer A. Abd Elrahman et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019)

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Article Chemistry, Multidisciplinary

Biomolecular Functionalization of a Nanomaterial To Control Stability and Retention within Live Cells

Mitchell Gravely et al.

NANO LETTERS (2019)

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Article Chemistry, Multidisciplinary

Spray-Dried Hierarchical Aggregates of Iron Oxide Nanoparticles and Their Functionalization for Downstream Processing in Biotechnology

Lennart Kleinfeldt et al.

ACS OMEGA (2019)

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Review Materials Science, Biomaterials

Biomedical and bioactive engineered nanomaterials for targeted tumor photothermal therapy: A review

Wenfeng Wei et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

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Article Chemistry, Multidisciplinary

Antibacterial Carbon-Based Nanomaterials

Qi Xin et al.

ADVANCED MATERIALS (2019)

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Article Biophysics

Functionalized MoS2-nanosheets for targeted drug delivery and chemo-photothermal therapy

Xueyi Zhang et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

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Article Materials Science, Biomaterials

Nanotechnology-based biomaterials for orthopaedic applications: Recent advances and future prospects

Sandeep Kumar et al.

Materials Science & Engineering C-Materials for Biological Applications (2019)

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Review Chemistry, Multidisciplinary

X-ray-activated nanosystems for theranostic applications

Xiaofeng Chen et al.

CHEMICAL SOCIETY REVIEWS (2019)

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Review Materials Science, Biomaterials

Antibody-guided nanomedicines as novel breakthrough therapeutic, diagnostic and theranostic tools

Ghazal Farahavar et al.

BIOMATERIALS SCIENCE (2019)

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Proceedings Paper Nuclear Science & Technology

The Analysis of Dimple Geometry on Artificial Hip Joint to the Performance of Lubrication

Hasan Basri et al.

SYMPOSIUM OF EMERGING NUCLEAR TECHNOLOGY AND ENGINEERING NOVELTY (SENTEN 2018) (2019)

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Article Engineering, Biomedical

Dual non-viral gene delivery from microparticles within 3D high-density stem cell constructs for enhanced bone tissue engineering

Alexandra McMillan et al.

BIOMATERIALS (2018)

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Review Pharmacology & Pharmacy

Strategies for the enhanced intracellular delivery of nanomaterials

Claudia Azevedo et al.

DRUG DISCOVERY TODAY (2018)

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Article Biochemistry & Molecular Biology

Gelatin - Oxidized carboxymethyl cellulose blend based tubular electrospun scaffold for vascular tissue engineering

Jincy Joy et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

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Article Biochemistry & Molecular Biology

Targeting and sensing of some cancer cells using folate bioreceptor functionalized nitrogen-doped graphene quantum dots

Jafar Soleymani et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

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Review Chemistry, Analytical

Advances in the design of nanomaterial-based electrochemical affinity and enzymatic biosensors for metabolic biomarkers: A review

Leila Farzin et al.

MICROCHIMICA ACTA (2018)

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Review Chemistry, Physical

Multifunctional nucleic acid nanostructures for gene therapies

Jianbing Liu et al.

NANO RESEARCH (2018)

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Article Chemistry, Multidisciplinary

DNA-templated nanoparticle complexes for photothermal imaging and labeling of cancer cells

Ganglin Wang et al.

NANOSCALE (2018)

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Review Nanoscience & Nanotechnology

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

Alyona Sukhanova et al.

NANOSCALE RESEARCH LETTERS (2018)

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Review Nanoscience & Nanotechnology

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

Alyona Sukhanova et al.

NANOSCALE RESEARCH LETTERS (2018)

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Review Cell & Tissue Engineering

Stem cells as delivery vehicles for regenerative medicine-challenges and perspectives

Luminita Labusca et al.

WORLD JOURNAL OF STEM CELLS (2018)

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Review Oncology

Photodynamic Therapy for Metastatic Melanoma Treatment: A Review

Channay Naidoo et al.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2018)

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Article Materials Science, Biomaterials

Preparation of mussel-inspired injectable hydrogels based on dual-functionalized alginate with improved adhesive, self-healing, and mechanical properties

Shifeng Yan et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Review Biotechnology & Applied Microbiology

Nano based drug delivery systems: recent developments and future prospects

Jayanta Kumar Patra et al.

JOURNAL OF NANOBIOTECHNOLOGY (2018)

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Article Materials Science, Biomaterials

Bilayered PLGA/PLGA-HAp Composite Scaffold for Osteochondral Tissue Engineering and Tissue Regeneration

Xiangyu Liang et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)

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Article Nanoscience & Nanotechnology

Functionalized selenium nanopartices for targeted delivery of doxorubicin to improve non-small-cell lung cancer therapy

Yu Xia et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

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Review Pharmacology & Pharmacy

Nanotechnology advances for hair loss

Maira N. Pereira et al.

THERAPEUTIC DELIVERY (2018)

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Review Chemistry, Multidisciplinary

Biomedical applications of functional peptides in nano-systems

Lei Rong et al.

MATERIALS TODAY CHEMISTRY (2018)

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Article Engineering, Biomedical

Polyethylene glycol functionalized carbon nanotubes/gelatin-chitosan nanocomposite: An approach for significant drug release

Sadia Sharmeen et al.

BIOACTIVE MATERIALS (2018)

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Review Biotechnology & Applied Microbiology

Tissue Engineering and Cell-Based Therapies for Fractures and Bone Defects

Jose R. Perez et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2018)

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Review Pharmacology & Pharmacy

Surface functionalization of polymeric nanoparticles for tumor drug delivery: approaches and challenges

Noura H. Abd Ellah et al.

EXPERT OPINION ON DRUG DELIVERY (2017)

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Article Biotechnology & Applied Microbiology

Ciprofloxacin HCl-loaded calcium carbonate nanoparticles: preparation, solid state characterization, and evaluation of antimicrobial effect against Staphylococcus aureus

Solmaz Maleki Dizaj et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2017)

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Article Materials Science, Biomaterials

Sodium alginate-polyvinyl alcohol-bovin serum albumin coated Fe3O4 nanoparticles as anticancer drug delivery vehicle: Doxorubicin loading and in vitro release study and cytotoxicity to HepG2 and L02 cells

G. Prabha et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

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Article Materials Science, Biomaterials

Antibacterial SnO2 nanorods as efficient fillers of poly(propylene fumarate-co-ethylene glycol) biomaterials

Ana M. Diez-Pascual et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

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Article Chemistry, Multidisciplinary

Cost effective surface functionalization of gold nanoparticles with a mixed DNA and PEG monolayer for nanotechnology applications

Risheng Wang et al.

RSC ADVANCES (2017)

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Article Chemistry, Multidisciplinary

Enhancing the proliferation of MC3T3-E1 cells on casein phosphopeptide-biofunctionalized 3D reduced-graphene oxide/polypyrrole scaffolds

Weibo Jie et al.

RSC ADVANCES (2017)

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Article Materials Science, Biomaterials

Multifunctional poly(glycolic acid-co-propylene fumarate) electrospun fibers reinforced with graphene oxide and hydroxyapatite nanorods

Ana M. Diez-Pascual et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

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Article Pharmacology & Pharmacy

The Application of Nanomaterials in Stem Cell Therapy for Some Neurological Diseases

Guilong Zhang et al.

CURRENT DRUG TARGETS (2017)

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Review Pharmacology & Pharmacy

A Review on Potential of Proteins as an Excipient for Developing a Nano-Carrier Delivery System

Amrita Chakraborty et al.

CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS (2017)

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Article Chemistry, Analytical

Papain-functionalized gold nanoparticles as heterogeneous biocatalyst for bioanalysis and biopharmaceuticals analysis

Siyao Liu et al.

ANALYTICA CHIMICA ACTA (2017)

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Review Chemistry, Multidisciplinary

Nanomaterials for In Vivo Imaging

Bryan Ronain Smith et al.

CHEMICAL REVIEWS (2017)

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Article Nanoscience & Nanotechnology

Tumor-Homing and Penetrating Peptide-Functionalized Photosensitizer-Conjugated PEG-PLA Nanoparticles for Chemo-Photodynamic Combination Therapy of Drug-Resistant Cancer

Xingye Feng et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Article Nanoscience & Nanotechnology

Poly(propylene fumarate)/Polyethylene Glycol-Modified Graphene Oxide Nanocomposites for Tissue Engineering

Ana M. Diez-Pascual et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Article Nanoscience & Nanotechnology

Hybrid Iron Oxide-Graphene Oxide-Polysaccharides Microcapsule: A Micro-Matryoshka for On-Demand Drug Release and Antitumor Therapy In Vivo

Lin Deng et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Article Chemistry, Multidisciplinary

Albumin Carriers for Cancer Theranostics: A Conventional Platform with New Promise

Qian Chen et al.

ADVANCED MATERIALS (2016)

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Article Biotechnology & Applied Microbiology

Surface Functionalization of Nanobiomaterials for Application in Stem Cell Culture, Tissue Engineering, and Regenerative Medicine

Deepti Rana et al.

BIOTECHNOLOGY PROGRESS (2016)

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Article Dentistry, Oral Surgery & Medicine

Human treated dentin matrices combined with Zn-doped, Mg-based bioceramic scaffolds and human dental pulp stem cells towards targeted dentin regeneration

Athina Bakopoulou et al.

DENTAL MATERIALS (2016)

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Article Chemistry, Inorganic & Nuclear

High Loading of Pd Nanoparticles by Interior Functionalization of MOFs for Heterogeneous Catalysis

Bappaditya Gole et al.

INORGANIC CHEMISTRY (2016)

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Review Engineering, Biomedical

Current investigations into magnetic nanoparticles for biomedical applications

Xiaoming Li et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2016)

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Review Chemistry, Multidisciplinary

Current applications of nanoparticles in infectious diseases

Hinojal Zazo et al.

JOURNAL OF CONTROLLED RELEASE (2016)

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Article Materials Science, Multidisciplinary

Magnetite nanoparticles for cancer diagnosis, treatment, and treatment monitoring: recent advances

Richard A. Revia et al.

MATERIALS TODAY (2016)

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Article Biochemistry & Molecular Biology

Near-Infrared Emitting PbS Quantum Dots for in Vivo Fluorescence Imaging of the Thrombotic State in Septic Mouse Brain

Yukio Imamura et al.

MOLECULES (2016)

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Review Biology

Quantum dots-DNA bioconjugates: synthesis to applications

Anusuya Banerjee et al.

INTERFACE FOCUS (2016)

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Article Multidisciplinary Sciences

Multi-functionalized carbon dots as theranostic nanoagent for gene delivery in lung cancer therapy

Yu-Fen Wu et al.

SCIENTIFIC REPORTS (2016)

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Article Materials Science, Biomaterials

Electrospun fibers of chitosan-grafted polycaprolactone/poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) blends

Ana M. Diez-Pascual et al.

JOURNAL OF MATERIALS CHEMISTRY B (2016)

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Review Pharmacology & Pharmacy

Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials

Eun Ji Hong et al.

ACTA PHARMACEUTICA SINICA B (2016)

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Article Chemistry, Multidisciplinary

Determination of riboflavin based on fluorescence quenching by graphene dispersions in polyethylene glycol

Ana M. Diez-Pascual et al.

RSC ADVANCES (2016)

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Article Nanoscience & Nanotechnology

Nano-TiO2 Reinforced PEEK/PEI Blends as Biomaterials for Load-Bearing Implant Applications

Ana M. Diez-Pascual et al.

ACS APPLIED MATERIALS & INTERFACES (2015)

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Article Biochemistry & Molecular Biology

In Vitro and In Vivo Tumor Targeted Photothermal Cancer Therapy Using Functionalized Graphene Nanoparticles

Sung Han Kim et al.

BIOMACROMOLECULES (2015)

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Article Biochemistry & Molecular Biology

Wound Healing Bionanocomposites Based on Castor Oil Polymeric Films Reinforced with Chitosan-Modified ZnO Nanoparticles

Ana M. Diez-Pascual et al.

BIOMACROMOLECULES (2015)

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Review Oncology

Nanotechnology: Future of Oncotherapy

Kshipra M. Gharpure et al.

CLINICAL CANCER RESEARCH (2015)

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Review Engineering, Chemical

Critical Review on the Toxicity of Some Widely Used Engineered Nanoparticles

Varsha Srivastava et al.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2015)

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Article Materials Science, Ceramics

Ceramics and ceramic coatings in orthopaedics

B. J. McEntire et al.

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY (2015)

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Article Chemistry, Physical

Combined Effect of a Microporous Layer and Type I Collagen Coating on a Biphasic Calcium Phosphate Scaffold for Bone Tissue Engineering

Mun-Hwan Lee et al.

MATERIALS (2015)

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Article Chemistry, Multidisciplinary

WS2 inorganic nanotubes reinforced poly(L-lactic acid)/hydroxyapatite hybrid composite biomaterials

Mohammed Naffakh et al.

RSC ADVANCES (2015)

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Article Chemistry, Multidisciplinary

Antimicrobial and sustainable food packaging based on poly(butylene adipate-co-terephthalate) and electrospun chitosan nanofibers

Ana M. Diez-Pascual et al.

RSC ADVANCES (2015)

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Article Materials Science, Biomaterials

Development of linseed oil-TiO2 green nanocomposites as antimicrobial coatings

Ana M. Diez-Pascual et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

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Review Materials Science, Biomaterials

Engineering and functionalization of biomaterials via surface modification

Guosong Wu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

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Article Nanoscience & Nanotechnology

Inorganic-Organic Thin Implant Coatings Deposited by Lasers

Felix Sima et al.

ACS APPLIED MATERIALS & INTERFACES (2015)

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Article Nanoscience & Nanotechnology

Toxicity screenings of nanomaterials: challenges due to interference with assay processes and components of classic in vitro tests

Rina Guadagnini et al.

NANOTOXICOLOGY (2015)

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Article Nanoscience & Nanotechnology

Cytotoxicity of TiO2 nanoparticles to mussel hemocytes and gill cells in vitro: Influence of synthesis method, crystalline structure, size and additive

Alberto Katsumiti et al.

NANOTOXICOLOGY (2015)

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Article Nanoscience & Nanotechnology

High-Performance Aminated Poly(phenylene sulfide)/ZnO Nanoconnposites for Medical Applications

Ana M. Diez-Pascual et al.

ACS APPLIED MATERIALS & INTERFACES (2014)

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Article Nanoscience & Nanotechnology

Epoxidized Soybean Oil/ZnO Biocomposites for Soft Tissue Applications: Preparation and Characterization

Ana M. Diez-Pascual et al.

ACS APPLIED MATERIALS & INTERFACES (2014)

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Article Engineering, Biomedical

Self-crosslinked oxidized alginate/gelatin hydrogel as injectable, adhesive biomimetic scaffolds for cartilage regeneration

Biji Balakrishnan et al.

ACTA BIOMATERIALIA (2014)

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Article Chemistry, Multidisciplinary

Mesoporous Silica Nanoparticles: Selective Surface Functionalization for Optimal Relaxometric and Drug Loading Performances

Meryem Bouchoucha et al.

ADVANCED FUNCTIONAL MATERIALS (2014)

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Article Biochemical Research Methods

Evaluation of the Cytotoxic Effects of PLGA Coated Iron Oxide Nanoparticles as a Carrier of 5-Fluorouracil and Mega-Voltage X-Ray Radiation in DU145 Prostate Cancer Cell Line

Zahra Hajikarimi et al.

IEEE TRANSACTIONS ON NANOBIOSCIENCE (2014)

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Article Physics, Applied

Graphene oxide coating facilitates the bioactivity of scaffold material for tissue engineering

Erika Nishida et al.

JAPANESE JOURNAL OF APPLIED PHYSICS (2014)

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Article Materials Science, Multidisciplinary

Cooperative entry of nanoparticles into the cell

Jiuling Wang et al.

JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS (2014)

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Article Chemistry, Multidisciplinary

Functionalized Mesoporous Silica Nanoparticles with Mucoadhesive and Sustained Drug Release Properties for Potential Bladder Cancer Therapy

Quan Zhang et al.

LANGMUIR (2014)

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Article Materials Science, Biomaterials

Suspension thermal spraying of hydroxyapatite: Microstructure and in vitro behaviour

Giovanni Bolelli et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2014)

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Review Polymer Science

Surface engineering of nanoparticles for therapeutic applications

Kenya Kobayashi et al.

POLYMER JOURNAL (2014)

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Article Chemistry, Multidisciplinary

Robust Microcapsules with Controlled Permeability from Silk Fibroin Reinforced with Graphene Oxide

Chunhong Ye et al.

SMALL (2014)

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Article Food Science & Technology

Crosslinked thiolated starch coated Fe3O4 magnetic nanoparticles: Effect of montmorillonite and crosslinking density on drug delivery properties

Chinmayee Saikia et al.

STARCH-STARKE (2014)

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Article Materials Science, Biomaterials

Effect of TiO2 nanoparticles on the performance of polyphenylsulfone biomaterial for orthopaedic implants

Ana M. Diez-Pascual et al.

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