期刊
DRUG DESIGN DEVELOPMENT AND THERAPY
卷 16, 期 -, 页码 739-748出版社
DOVE MEDICAL PRESS LTD
DOI: 10.2147/DDDT.S356880
关键词
lidocaine; TAP block; bariatric surgery; postoperative recovery; postoperative pain
This study aimed to compare the effect of intravenous infusion of lidocaine with ultrasound-guided transverse abdominal plane (TAP) block on postoperative recovery and analgesia in patients undergoing bariatric surgery. The results showed that both lidocaine infusion and TAP block provided good postoperative recovery and analgesia, but lidocaine infusion had better analgesic effect at 12 hours and 24 hours postoperatively compared with TAP block.
Purpose: To investigate the effect of intravenous infusion of lidocaine compared with ultrasound-guided transverse abdominal plane (TAP) block on the quality of postoperative recovery and analgesic effect in patients undergoing bariatric surgery. Patients and Methods: Ninety-nine ASA II-III patients scheduled for elective laparoscopic bariatric surgery were randomized into the lidocaine group (group L), transverse abdominal plane block group (group T), and control group (group C). Group L: a loading dose of 1.5 mg/kg lidocaine was given at induction, followed by 2 mg.kg(-1).h(-1) maintenance until the end of surgery. Group T: ultrasound-guided bilateral administration of 0.25% ropivacaine in the transverse abdominal plane was given after induction of general anesthesia. Group C: no additional treatment was performed. Quality of recovery-40 (QoR-40) was assessed at 24 h after surgery. Consumption of propofol and remifentanil, visual analog scale (VAS) pain scores at rest at 0, 6, 12, and 24 h postoperatively, time to return of intestinal function, use of remedial analgesics within 24 h after surgery, adverse reactions were recorded. Results: Compared with Group C, Group L and Group T had higher QoR-40 scores at 24 h postoperatively, and the difference was statistically significant (P=0.002 and P=0.003, respectively). However, there was no difference between Group L and Group T (P=0.128). In addition, compared with those of Group T and Group C, VAS scores at 12 h and 24 h postoperatively were lower in Group L (P <0.0166). Conclusion: Both intravenous infusion of lidocaine and ultrasound-guided TAP block provided good postoperative recovery and postoperative analgesia for patients with bariatric surgery, and intravenous infusion of lidocaine provided better analgesia at 12 h and 24 h postoperatively compared with TAP block.
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