期刊
BIOMEDICAL OPTICS EXPRESS
卷 13, 期 4, 页码 1899-1911出版社
Optica Publishing Group
DOI: 10.1364/BOE.452609
关键词
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资金
- Fundacja na rzecz Nauki Polskiej [First TEAM/2017-4/39, MAB/2019/12, TEAM TECH/2016-3/20]
- Narodowe Centrum Nauki [2016/23/B/ST2/00752]
We report the development of a widely-tunable femtosecond fiber laser system and its application for two-photon vision studies. The system offers efficient and safe two-photon stimulation and can be used for measuring the two-photon scotopic spectral sensitivity in humans.
We report the development of a widely-tunable femtosecond fiber laser system and its application for two-photon vision studies. The source is based on an Er-doped fiber laser with spectral shift up to 2150 nm, followed by a second harmonic generation module to generate a frequency-doubled beam tunable from 872 to 1075 nm. The source delivers sub-230 fs pulses with nearly-constant duration over the entire tuning range, with output powers between 0.68-1.24 mW, which corresponds to a pulse energy of 13.2-24.1 pJ. Such pulse energy is sufficient for employing a system for measurements of two-photon scotopic spectral sensitivity of two-photon vision in humans. The laser parameters allow for very efficient and safe two-photon stimulation of the human visual system, as proved by a good separation between one-and two-photon thresholds for wavelengths below 950 nm, which we have confirmed for 3 healthy subjects. (c) 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement
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