期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 18, 期 8, 页码 784-790出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2016.1157077
关键词
Asteraceae; polyacetylene glucosides; Coreopsis tinctoria; 3T3-L1; antiadipogenic effect
资金
- National Natural Science Foundation of China [81403078, 30900244]
- China Postdoctoral Science Foundation [2013M530402]
Based on characteristic UV spectrum of the ene-diyne chromophore, one new polyacetylene glucoside and three known polyacetylene glucosides have been isolated from the EtOH extract of Coreopsis tinctoria. Their chemical structures were determined by detailed spectroscopic analysis and by comparison with literature data. Compounds 1-2 were tested for their antiadipogenic effects on 3T3-L1 adipocytes, and both of them reduced lipid accumulation dose-dependently in 3T3-L1 adipocytes.
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