期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 18, 期 10, 页码 913-920出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2016.1187603
关键词
Lespedeza cuneata; lignanoside; hepatoprotective activities
资金
- National Mega-project for Innovative Drugs [2012ZX09301002-002]
- National Natural Science Foundation of China [81560632, 81202546]
Three new lignanosides (+)-(8S,7S,8S)-burselignan-9-O--d-glucopyrano side (1), (+)-(8R,7S,8R)-isolariciresinol-9-O--d-fucopyranoside (2), (-)-(8S, 7R,8R)-methoxyisoariciresinol-9-O--l-rhamnoside (3), along with four known compounds, were isolated from the aerial parts of Lespedeza cuneata (Dum.Cours.) G.Don. The fucopyranoside has not been reported in this genus previously. Their structures and absolute configurations were elucidated on the basis of comprehensive spectroscopic analyses (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with known analogues in the literature. Compounds 2 and 6 showed moderate hepatoprotective activities.
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