期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 18, 期 7, 页码 629-636出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2015.1136291
关键词
Chukrasia tabularis; Meliaceae; limonoid; -glucosidase activity
资金
- Agro-scientific Research in the Public Interest [201303117]
- National Support Science and Technology Subject [2013BAI11B04]
- Major Technology Project of Hainan Province [ZDZX2013008-4]
- National Nonprofit Institute Research Grant of CATAS-ITBB [ITBB2015RC03]
Phytochemical investigation on the stems of C. tabularis (Meliaceae) led to the isolation of two new phragmalin-type limonoids, named tabularisins S and T (1-2), along with five known ones (3-7). The structures of the new limonoids were established by spectroscopic methods including UV, IR, HRESIMS, and 1D and 2D NMR. All the compounds were evaluated for -glucosidase inhibitory activity in vitro. Compounds 2 and 3 exhibited significant inhibitory activity against -glucosidase with IC50 values of 0.15 and 0.03mM, respectively (acarbose as positive control, IC50 0.95mM).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据