4.8 Article

A specialized bone marrow microenvironment for fetal haematopoiesis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics

Suwei Gao et al.

Summary: This study identified novel transcriptionally heterogeneous subsets of HSC/MPP in mouse fetal liver, including a CD93-enriched subset with enhanced stem cell properties, as well as 'pocket-like' units called HSC PLUS enriched with growth factors and niche cells. Unexpectedly, macrophages were found to play a supportive role in HSC/MPP expansion, along with growth factors such as MDK, PTN, and IGFBP5. Furthermore, while conserved cell-cell interactions and expansion mechanisms were observed between mouse and human FL HSCs/MPPs, their transcriptome signatures showed divergence.

CELL RESEARCH (2022)

Review Physiology

Regulation of Hemogenic Endothelial Cell Development and Function

Yinyu Wu et al.

Summary: Embryonic definitive hematopoiesis generates HSPCs essential for the adult blood system. Intensive investigation into the regulation mechanisms of this process aims to generate autologous HSPCs for clinical applications. The impact of hemogenic endothelial cell development on adult hematopoiesis is also discussed.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 83 (2021)

Article Cell & Tissue Engineering

Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis

Anna Maria Ranzoni et al.

Summary: Using single-cell RNA sequencing and single-cell assay for transposase-accessible chromatin sequencing, researchers identified three highly proliferative oligopotent progenitor populations downstream of hematopoietic stem cells (HSCs)/multipotent progenitors (MPPs) in human fetal liver and bone marrow. They observed dynamic changes in chromatin accessibility and lineage-specific transcription factor activity along the differentiation trajectory, providing a useful framework for future investigation of human developmental hematopoiesis.

CELL STEM CELL (2021)

Article Hematology

Identification of CXCL12-abundant reticular cells in human adult bone marrow

Kazunari Aoki et al.

Summary: Human bone marrow contains cells expressing high levels of CXCL12, SCF, FOXC1 and EBF3, with the potential to differentiate into adipocytes and osteoblasts. These cells may play a role in various hematological disorders.

BRITISH JOURNAL OF HAEMATOLOGY (2021)

Article Hematology

Dopamine signaling regulates hematopoietic stem and progenitor cell function

Yang Liu et al.

Summary: This study reveals that dopamine derived from sympathetic nerves directly controls the behavior of hematopoietic stem and progenitor cells through D-2 subfamily dopamine receptors. Dopamine signaling affects proliferation, frequency, and transplantation efficiency of HSPCs.
Article Cell Biology

Regional specialization and fate specification of bone stromal cells in skeletal development

Kishor K. Sivaraj et al.

Summary: Bone stroma plays a crucial role in regulating osteogenesis and hematopoiesis, as well as fracture healing and disease processes. BMSCs from different bone regions, such as metaphysis and diaphysis, exhibit distinct characteristics and functions. The fate of BMSCs is controlled by signaling pathways involving PDGFR beta and transcription factor Jun-B, contributing to bone development and our understanding of BMSC lineage relationships and differentiation.

CELL REPORTS (2021)

Article Multidisciplinary Sciences

Live-animal imaging of native haematopoietic stem and progenitor cells

Constantina Christodoulou et al.

NATURE (2020)

Review Cell Biology

Dynamic responses of the haematopoietic stem cell niche to diverse stresses

Antoniana Batsivari et al.

NATURE CELL BIOLOGY (2020)

Article Multidisciplinary Sciences

Lineage tracing on transcriptional landscapes links state to fate during differentiation

Caleb Weinreb et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

The N-glycome regulates the endothelial-to-hematopoietic transition

Dionna M. Kasper et al.

SCIENCE (2020)

Review Oncology

Bone marrow niches in haematological malignancies

Simon Mendez-Ferrer et al.

NATURE REVIEWS CANCER (2020)

Review Cell Biology

Haematopoietic stem cell activity and interactions with the niche

Sandra Pinho et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Article Biochemistry & Molecular Biology

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia

Ninib Baryawno et al.

Article Multidisciplinary Sciences

The bone marrow microenvironment at single-cell resolution

Anastasia N. Tikhonova et al.

NATURE (2019)

Article Multidisciplinary Sciences

Decoding human fetal liver haematopoiesis

Dorin-Mirel Popescu et al.

NATURE (2019)

Review Developmental Biology

The hematopoietic stem cell niche: from embryo to adult

Xin Gao et al.

DEVELOPMENT (2018)

Article Multidisciplinary Sciences

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow

Chunliang Xu et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Structural and dynamic characterization of human Wnt2-Fzd7 complex using computational approaches

Hourieh Kalhor et al.

JOURNAL OF MOLECULAR MODELING (2018)

Article Medicine, Research & Experimental

Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression

Peipei Guo et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Cell Biology

Cell-matrix signals specify bone endothelial cells during developmental osteogenesis

Urs H. Langen et al.

NATURE CELL BIOLOGY (2017)

Article Multidisciplinary Sciences

Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis

Hyun-Woo Jeong et al.

NATURE COMMUNICATIONS (2017)

Article Medicine, General & Internal

Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood

Vilma Barroca et al.

EBIOMEDICINE (2017)

Review Biochemistry & Molecular Biology

The role of Wnt signaling in hematopoietic stem cell development

Jenna Richter et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)

Review Cell & Tissue Engineering

Hematopoietic Stem Cell Gene Therapy: Progress and Lessons Learned

Richard A. Morgan et al.

CELL STEM CELL (2017)

Review Immunology

Adult haematopoietic stem cell niches

Genevieve M. Crane et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Article Multidisciplinary Sciences

Fetal liver hematopoietic stem cell niches associate with portal vessels

Jalal A. Khan et al.

SCIENCE (2016)

Review Cell Biology

Regulation of Hematopoiesis and Osteogenesis by Blood Vessel-Derived Signals

Saravana K. Ramasamy et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 32 (2016)

Article Multidisciplinary Sciences

Age-dependent modulation of vascular niches for haematopoietic stem cells

Anjali P. Kusumbe et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

c-kit(+) cells adopt vascular endothelial but not epithelial cell fates during lung maintenance and repair

Qiaozhen Liu et al.

NATURE MEDICINE (2015)

Article Biochemistry & Molecular Biology

Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin

Ayako Nakamura-Ishizu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Biochemistry & Molecular Biology

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion

Ingmar Bruns et al.

NATURE MEDICINE (2014)

Article Developmental Biology

Notch controls retinal blood vessel maturation and quiescence

Manuel Ehling et al.

DEVELOPMENT (2013)

Article Multidisciplinary Sciences

Arteriolar niches maintain haematopoietic stem cell quiescence

Yuya Kunisaki et al.

NATURE (2013)

Article Cell Biology

Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis

Michael G. Poulos et al.

CELL REPORTS (2013)

Review Biochemistry & Molecular Biology

Developmental changes in hematopoietic stem cell properties

Michael R. Copley et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2013)

Article Biochemistry & Molecular Biology

Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche

Ryohichi Sugimura et al.

Article Immunology

Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow

Anna Mansour et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

Article Multidisciplinary Sciences

Endothelial and perivascular cells maintain haematopoietic stem cells

Lei Ding et al.

NATURE (2012)

Review Cell & Tissue Engineering

On the origin of hematopoietic stem cells: Progress and controversy

Jean-Charles Boisset et al.

STEM CELL RESEARCH (2012)

Article Reproductive Biology

WNT2 Regulates DNA Synthesis in Mouse Granulosa Cells Through Beta-Catenin

Hong-Xing Wang et al.

BIOLOGY OF REPRODUCTION (2010)

Article Developmental Biology

A sensitive and bright single-cell resolution live imaging reporter of Wnt/β-catenin signaling in the mouse

Anna Ferrer-Vaquer et al.

BMC DEVELOPMENTAL BIOLOGY (2010)

Article Developmental Biology

Generation of Mice with a Conditional Null Allele for Wntless

April C. Carpenter et al.

GENESIS (2010)

Article Biochemistry & Molecular Biology

Dynamic interaction networks in a hierarchically organized tissue

Daniel C. Kirouac et al.

MOLECULAR SYSTEMS BIOLOGY (2010)

Review Medicine, Research & Experimental

Hematopoietic stem cell: self-renewal versus differentiation

Jun Seita et al.

WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2010)

Review Cell & Tissue Engineering

Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis

Sachin Malhotra et al.

CELL STEM CELL (2009)

Article Multidisciplinary Sciences

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

Cristina Lo Celso et al.

NATURE (2009)

Article Cell & Tissue Engineering

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

Ann C. Zovein et al.

CELL STEM CELL (2008)

Article Biochemistry & Molecular Biology

G(12)-G(13)-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension

Angela Wirth et al.

NATURE MEDICINE (2008)

Article Developmental Biology

A global double-fluorescent cre reporter mouse

Mandar Deepak Muzumdar et al.

GENESIS (2007)

Article Biochemistry & Molecular Biology

Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

Orit Kollet et al.

NATURE MEDICINE (2006)

Review Medicine, General & Internal

Medical progress: Hematopoietic stem-cell transplantation

EA Copelan

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Multidisciplinary Sciences

Wnt signalling in stem cells and cancer

T Reya et al.

NATURE (2005)

Article Multidisciplinary Sciences

A role for Wnt signalling in self-renewal of haematopoietic stem cells

T Reya et al.

NATURE (2003)

Article Immunology

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

J de Boer et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2003)

Article Biochemistry & Molecular Biology

Frizzled-9 is activated by Wnt-2 and functions in Wnt/β-catenin signaling

T Karasawa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)