4.7 Article

DNAJC24 is a potential therapeutic target in hepatocellular carcinoma through affecting ammonia metabolism

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Review Biochemistry & Molecular Biology

Sex and Race-Related DNA Methylation Changes in Hepatocellular Carcinoma

Wenrui Ye et al.

Summary: Hepatocellular carcinoma (HCC) is a common cancer with disparities in occurrence among different genders and races/ethnic groups due to genetic and epigenetic factors. Research focuses on genetic mutations and DNA methylation changes to address health disparities in gastrointestinal malignancies using epigenetic approaches.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Gastroenterology & Hepatology

Discovery of a Carbamoyl Phosphate Synthetase 1-Deficient HCC Subtype With Therapeutic Potential Through Integrative Genomic and Experimental Analysis

Tong Wu et al.

Summary: This study identified a CPS1-deficient HCC subtype through big-data mining, explored its tumorigenesis mechanism, and found potential therapeutic targets related to metabolic reprogramming in liver cancer.

HEPATOLOGY (2021)

Article Cell Biology

PNO1 regulates autophagy and apoptosis of hepatocellular carcinoma via the MAPK signaling pathway

Zhiqiang Han et al.

Summary: PNO1 is overexpressed in hepatocellular carcinoma (HCC) and promotes autophagy while inhibiting apoptosis of HCC cells through the MAPK signaling pathway, thereby advancing the progression of HCC.

CELL DEATH & DISEASE (2021)

Review Medicine, Research & Experimental

HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer

Ellen C. de Heer et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Review Oncology

Acidosis and cancer: from mechanism to neutralization

Arig Ibrahim-Hashim et al.

CANCER AND METASTASIS REVIEWS (2019)

Review Cell Biology

Regulation of heat shock transcription factors and their roles in physiology and disease

Rocio Gomez-Pastor et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

Heat Stress and Hepatic Laser Thermal Ablation Induce Hepatocellular Carcinoma Growth: Role of PI3K/mTOR/AKT Signaling

Danielle E. Jondal et al.

RADIOLOGY (2018)

Review Medical Laboratory Technology

Nrf2-p62 autophagy pathway and its response to oxidative stress in hepatocellular carcinoma

Desiree Bartolini et al.

TRANSLATIONAL RESEARCH (2018)

Review Endocrinology & Metabolism

Starvation, Stress Resistance, and Cancer

Roberta Buono et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2018)

Review Biochemistry & Molecular Biology

Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach

Suman Chatterjee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemistry & Molecular Biology

Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis

Pattarawut Sopha et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Review Endocrinology & Metabolism

Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells

Inge M. N. Wortel et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)

Article Oncology

Angiogenesis and Metabolism: Entwined for Therapy Resistance

Gabriela Jimenez-Valerio et al.

TRENDS IN CANCER (2017)

Article Biochemistry & Molecular Biology

High mobility group A1 protein modulates autophagy in cancer cells

Andrea Conte et al.

CELL DEATH AND DIFFERENTIATION (2017)

Review Biochemistry & Molecular Biology

Emerging Biological Principles of Metastasis

Arthur W. Lambert et al.

Review Cell Biology

HSF1 Guardian of Proteostasis in Cancer

Chengkai Dai et al.

TRENDS IN CELL BIOLOGY (2016)

Article Oncology

DNAJB1 destabilizes PDCD5 to suppress p53-mediated apoptosis

Xiandan Cui et al.

CANCER LETTERS (2015)

Review Biochemistry & Molecular Biology

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

L. Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2015)

Article Biochemistry & Molecular Biology

DNAJC6 promotes hepatocellular carcinoma progression through induction of epithelial-mesenchymal transition

Tao Yang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Cell Biology

Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival

Alexandra N. Elsing et al.

JOURNAL OF CELL BIOLOGY (2014)

Review Medicine, Research & Experimental

Role of estrogen in hepatocellular carcinoma: is inflammation the key?

Liang Shi et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2014)

Editorial Material Cell Biology

Autophagy and ammonia

Heesun Cheong et al.

AUTOPHAGY (2012)

Article Oncology

HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem-like Cells

Satoshi Nishizawa et al.

CANCER RESEARCH (2012)

Review Biochemistry & Molecular Biology

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

Julius Anckar et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)

Review Cell Biology

Eaten alive: a history of macroautophagy

Zhifen Yang et al.

NATURE CELL BIOLOGY (2010)

Review Oncology

Heat-shock proteins in infection-mediated inflammation-induced tumorigenesis

Mark G. Goldstein et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2009)

Review Cell Biology

How to interpret LC3 immunoblotting

Noboru Mizushima et al.

AUTOPHAGY (2007)

Review Biochemistry & Molecular Biology

The diversity of the DnaJ/Hsp40 family, the crucial partners for Hsp70 chaperones

X-B. Qiu et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2006)

Article Biochemistry & Molecular Biology

Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance

Pedro A. Ortiz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Oncology

Angiogenesis and anti-angiogenesis in hepatocellular carcinoma

Domenico Ribatti et al.

CANCER TREATMENT REVIEWS (2006)

Review Medicine, Research & Experimental

Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways

HM Beere

JOURNAL OF CLINICAL INVESTIGATION (2005)